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Creatine and Parkinsons disease -

Zhenguang Li ; Zhenguang Li. Department of Neurology, Weihai Municipal Hospital, Binzhou Medical College, Weihai City, China. This Site. Google Scholar. Pengfei Wang ; Pengfei Wang. wpf Zhancai Yu ; Zhancai Yu. Yannan Cong ; Yannan Cong.

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Cite Icon Cite. toolbar search Search Dropdown Menu. toolbar search search input Search input auto suggest. Abstract Background: To investigate the effect of creatine and coenzyme Q10 CoQ10 combination therapy on mild cognitive impairment MCI in Parkinson's disease PD; PD-MCI and its influences on plasma phospholipid PL levels in PD-MCI.

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Stork C, Renshaw PF. Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research. Mol Psychiatry. Download references. This work was supported by funding from the National Natural Science Foundation of China No. The funding agencies had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.

ZL and LLC conceived and designed the study. WBP and JR performed the selection of studies, data-extraction. LYL and JJM drafted the review.

ZL and JJM carried out the statistical analysis and interpretation of data. All authors participated in revision the manuscript and the final approval of the manuscript.

None of the authors received financial support from companies, organizations, or other entities that may have affected the interpretation of the data. No financial conflicts of interest exist. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases, Affiliated Hospital of Guangdong Medical University, No.

Department of Neurology, Affiliated Hospital of Guangdong Medical University, No. Department of Neurology, Chenzhou No. You can also search for this author in PubMed Google Scholar. Correspondence to Zhou Liu or Li-Li Cui.

Open Access This article is distributed under the terms of the Creative Commons Attribution 4. Reprints and permissions. Mo, JJ. et al. BMC Neurol 17 , Download citation. Received : 07 November Accepted : 18 May Published : 02 June Anyone you share the following link with will be able to read this content:.

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Search all BMC articles Search. Download PDF. Results Five randomized controlled trials RCTs were selected, and participants were included in the analysis.

Conclusions Creatine has no observed benefit in PD patients, although more correlated studies are still needed. Methods Literature search Two authors independently conducted a systematic literature search of multiple databases, including the Cochrane Central Register of Controlled Trials, PUBMED, EMBASE, and other sources, for studies published through October Data extraction The data were collected in two steps.

Quality assessment Two authors independently assessed the validity of each study by determining the risk of bias according to the Cochrane Handbook for Systematic Reviews of Interventions Version 5. Level of evidence We determined the quality of evidence in each study using the Grades of Recommendation, Assessment, Development and Evaluation GRADE approach.

Statistical analysis The data analyses were performed using Review Manager Software Version 5. Results Search results and study characteristics The search strategy initially identified articles published prior to October Full size image.

Table 1 Characteristics of the studies included in the meta-analysis Full size table. Table 2 Baseline characteristics of the patient populations Full size table. Parashos, Sotirios A. Petrovitch, H. Rajan, S. Reichwein, S.

Roth, J. Schneider, J. Shannon, K. Simon, D. Simuni, T. Singer, C. Sudarsky, L. Tanner, C. Umeh, C. Williams, K. Wills, A. Writing Group for the NINDS Exploratory Trials in Parkinson Disease NET-PD Investigators,.

publication date published in JAMA Journal. keywords Comparative Studies Drugs and Drug Therapy Follow-Up Studies Parkinson Disease Patient Compliance Randomized Controlled Trials. volume

Zhenguang ParinsonsPengfei WangZhancai Yu Ceatine, Thermogenic workout routine CongHairong SunJiangshan ZhangCreatins ZhangChao SunCitrus fruit for immune system Creatine and Parkinsons diseaseXiaohua Ju; The Effect Thermogenic workout routine Creatine and Creatine and Parkinsons disease Q10 Combination Therapy Ceratine Mild Cognitive Impairment in Parkinson's Disease. Eur Neurol 1 April ; 73 : — Background: To investigate the effect of creatine and coenzyme Q10 CoQ10 combination therapy on mild cognitive impairment MCI in Parkinson's disease PD; PD-MCI and its influences on plasma phospholipid PL levels in PD-MCI. Methods: The demographic data of 75 PD-MCI patients who enrolled in this collaborative PD study were collected. These patients were evaluated using the Unified Parkinson's Disease Rating Scale UPDRS III and the Montreal Cognitive Assessment MoCA.

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New drugs for treatment of Parkinson’s disease By Editorial Team. Reviewed by: HU Medical Review Board Creatinee reviewed: May Dietary supplements are products that Polyphenols for detoxification Thermogenic workout routine eisease ingredient, such as a vitamin, mineral, amino acid, or herb. Also called nutritional supplements, they are taken by mouth and are intended to add nutritional value to the diet. Many people use dietary supplements for general health and well-being. People with PD also look to supplements to improve their health.