Error Include Weight loss pills valid email address. Phentermine looss itself Adipex-P, Lomaira also is used for weight loss. These medications are called GLP1-agonists. Clinical Trials.

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Possible side effects vary by medication and how it acts on your body. Most side effects are mild and most often improve if you continue to take the medication.

Rarely, serious side effects can occur. Choosing a medication to treat overweight or obesity is a decision between you and your health care professional. Important factors to consider include. How long you will need to take weight management medication depends on whether the drug helps you lose weight and keep it off and whether you experience serious side effects.

If you have lost enough weight to improve your health and are not experiencing serious side effects, your health care professional may advise you to stay on the medication indefinitely.

Your health care professional may also. Because obesity is a chronic disease, you may need to continue your new eating and physical activity habits and other behaviors for years—or even a lifetime—to improve your health and maintain a healthier weight. You probably will regain some weight after you stop taking weight management medication.

Developing and maintaining healthy eating habits and increasing physical activity may help you regain less weight or keep it off. Federal physical activity guidelines PDF, You may need to do more than minutes of moderate-intensity activity a week to reach or maintain your weight-loss goal.

Some, but not all, insurance plans cover medications that treat overweight and obesity. Contact your insurance provider to find out if your plan covers these medications. The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat Xenical, Alli , phentermine-topiramate Qsymia , naltrexone-bupropion Contrave , liraglutide Saxenda , and semaglutide Wegovy —for long-term use.

A sixth approved drug, setmelanotide IMCIVREE , is limited to people who have been diagnosed with one of three specific rare genetic disorders, which must be confirmed by genetic testing. You can keep taking these medications as long as you are benefiting from treatment and not experiencing serious side effects.

Some weight management medications that curb appetite are approved by the FDA for short-term use only, for up to 12 weeks. Although some health care professionals prescribe them for longer periods, not many research studies have looked at how safe and effective they are for long-term use.

Never take weight management medications if you are pregnant. If you are planning to get pregnant, you should also avoid these medications, as some of them may harm the fetus. By choosing an off-label medication to treat overweight and obesity, your health care professional may prescribe.

You should feel comfortable asking whether your health care professional is prescribing a medication that is not approved for treating overweight and obesity. Before using a medication, learn all you need to know about it.

Researchers are currently studying several new medications and combinations of medications in animals and people. Researchers are working to identify safer and more effective medications to help people who are overweight or have obesity lose weight and maintain a healthy weight for a long time.

NIDDK conducts and supports clinical trials in many diseases and conditions, including overweight and obesity. The trials look to find new ways to prevent, detect, or treat disease and improve quality of life.

Clinical trials—and other types of clinical studies —are part of medical research and involve people like you.

When you volunteer to take part in a clinical study, you help doctors and researchers learn more about disease and improve health care for people in the future. Researchers are studying many aspects of prescription medications to treat overweight or obesity, such a.

Find out if clinical studies are right for you. Watch a video of NIDDK Director Dr. Griffin P. Rodgers explaining the importance of participating in clinical trials.

You can view a filtered list of clinical studies on prescription medications to treat overweight and obesity that are federally funded, open, and recruiting at www.

You can expand or narrow the list to include clinical studies from industry, universities, and individuals; however, the National Institutes of Health does not review these studies and cannot ensure they are safe. Always talk with your health care provider before you participate in a clinical study.

This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases NIDDK , part of the National Institutes of Health. NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public.

Content produced by NIDDK is carefully reviewed by NIDDK scientists and other experts. NIDDK would like to thank: Kishore Gadde, M. English English Español. Weight Management Binge Eating Disorder Show child pages. Tips to Help You Get Active Show child pages. Weight-loss Metabolic and Bariatric Surgery Show child pages.

On this page: What are overweight and obesity? How common are overweight and obesity? How do weight management medications work? Who might benefit from weight management medications?

Can children or teenagers take weight management medications? Can medications replace physical activity and healthy eating habits as a way to lose weight? What are the benefits of using prescription medications to lose weight? What are the concerns about using prescription medications to lose weight?

Which weight management medication might work for me? How long will I need to take weight management medication? Will I regain some weight after I stop taking weight management medication?

Will insurance cover the cost of weight management medication? What medications are available to treat overweight and obesity?

What other medications for weight loss may be available in the future? Always talk to your doctor before starting or stopping any medicine. Any weight-loss medicine should be taken along with lifestyle changes, such as exercise and a healthy diet — not in place of them. Read more: What is primary care?

Learn why you should partner with a provider for your health from UC Davis Health. Wegovy is a popular weight-loss medication made by the same company as Ozempic , which has been in the news a lot recently. Wegovy is a weekly injection approved by the U. Food and Drug Administration FDA in for long-term weight management.

It's the first drug approved for this purpose since Both Wegovy and Ozempic include the same active ingredient semaglutide. However, Ozempic has lower doses of semaglutide and was developed for people with type 2 diabetes. Wegovy contains higher doses of semaglutide and was formatted to help with weight loss.

It's become a popular trend: taking Ozempic for weight loss. It's a once-weekly injection that was approved by the FDA for use in adults with type 2 diabetes. Ozempic is not approved for weight loss. However, semaglutide is approved for weight loss under the brand name Wegovy.

Ozempic can help people lose weight. However, experts recommend that people avoid using Ozempic for weight loss since it's meant for people with type 2 diabetes.

Talk to your doctor about starting Wegovy instead if you're looking to lose weight. Read more about Ozempic for weight loss: Does it work, and what do experts recommend? from UC Davis Health. There are no approved generic versions of either of these drugs, according to the FDA. Off-brand versions of these drugs have been seen at compounding pharmacies across the U.

People have reported adverse events to the FDA after using "generic" versions of semaglutide. Since people started off-label use of Ozempic for weight loss, type 2 diabetes patients who rely on the medication have struggled to find it.

Both Ozempic and Wegovy were listed on the FDA Drug Shortage List , as of September Like Ozempic , Mounjaro tirzepatide is another popular medication that has been used off label to help with weight loss.

It's approved for people with type 2 diabetes to help lower blood sugar. menu icon Menu. Cultivating Health. Enter search words search icon Search × Enter search words Subscribe to Cultivating Health Subscribe to our blog and receive notifications of new stories by email.

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