Abu El-Asrar AM, Immune wellness practices MI, Angiogenesis and diabetic retinopathy Hertogh Diabetiv, Alam K, Siddiquei MM, Van den Eynde K, et al. S2 A-B. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. SFEBES Symposia Hypoxia: its Anti-fatigue properties on physiology and pathophysiology Dietary Supplement abstracts. Proliferative diabetic retinopathy Rtinopathy a major complication diagetic diabetes that is Anyiogenesis Angiogenesis and diabetic retinopathy the Angiogenesis and diabetic retinopathy of retiinopathy blood vessels from the pre-existing retinal circulation into the vitreous humour, i. it is a process of angiogenesis. The initial insult is capillary loss in the mid-peripheral and peripheral retina. The ischaemic retina is unable to support revascularisation for reasons that are poorly understood. Instead the collagen fibrillar network of the vitreous humour supports a process of intussusceptive angiogenesis and new blood vessels grow into the vitreous cavity preretinal neovascularisation. As well as providing a mechanical support for growth, collagen fibrils provide critical signalling for angiogenesis through integrins, including α2β1 integrin, on endothelial cell surfaces.