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Study Finds Metformin Limits Exercise Gains \u0026 VO2 Max Introduction: An general, patients with type 2 diabetes Metformin and exercise lower cardiorespiratory fitness levels and perform exercise at lower intensities compared eexercise healthy Metflrmin. Metformin and exercise metformin MET exerclse Metformin and exercise shown to Clearing up nutrition myths the rate of perceived exertion RPE during exercise with a fixed intensity, MET per se may reduce self-selected exercise intensity. The aim of this study was to assess the effect of MET on self-selected exercise intensity. Methods: Healthy males were eligible for this crossover, counterbalanced study with two treatment periods: MET and placebo PLAeach lasting 17 days. The two periods were performed in randomized order.![Metformin and exercise Metformin and exercise](https://d3i71xaburhd42.cloudfront.net/ba2672bfb10c3767d0ab49d8a0bf9f9754c4d236/3-Figure1-1.png)
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