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Neuropathic pain in diabetes

Neuropathic pain in diabetes

Neuroppathic Neuropathic pain in diabetes of neuropathy is Neuropathic pain in diabetes dianetes problem in the primary care of people with diabetes and impedes the benefits of early diabetez, the management necessary to achieve improved glycemic control and the prevention of neuropathy-related sequelae Rosenstock J, Tuchman M, LaMoreaux L, et al. Arch Phys Med Rehabil. The Diabetes Control and Complications Trial Research Group. See more about diabetes research at the NIDDK. Partanen J, Niskanen L, Lehtinen J, et al. Evidence-based guideline: Treatment of painful diabetic neuropathy [published correction appears in Neurology.

Neuropathic pain in diabetes -

Diabetes affects as many as 29 million people in the U. More than 8 million people are either unaware or have yet to be diagnosed with the condition.

Patients with high blood sugar can experience a variety of health conditions, including diabetic nerve pain, often seen in the feet and legs first. Diabetic nerve pain will vary for each individual based on the severity of nerve damage.

It can seem like even the bed sheets are heavy and painful to lay down on. You may also experience difficulty picking up a spoon or fork to eat your meal or drop items on a regular basis.

Most of this is contributed to diabetic nerve pain. This innovative new therapy brings blood flow back to the nerves by opening the arteries in your hands and feet. Neuropathic Therapy Center Treatment Options More Articles.

Join us as we reveal our new campaign to support health, education, and research in our community! Get Details. Be sure to speak to your doctor about the best exercise for you based on your specific health and symptoms. If you go to a physical therapist, choose a trusted professional who understands neuropathy, diabetes, or otherwise, and can help you work through physical therapy methods without further nerve damage.

Proper attention to physical activity by an expert can prevent any further issues from occurring. Also keep in mind that physical therapy can soothe diabetic nerve pain, but not cure it.

Capsaicin cream Arthricare, Zostrix can block pain signals using an ingredient found in hot peppers. It is also available as a lotion, jelly, or patch, and can be applied to the skin where diabetic nerve pain is strong.

Research has found that applying capsaicin 0. That said, talk with your doctor before using treatments based on capsaicin. It can cause skin irritation and even an allergic reaction in some people. It may also interact with other drugs and might make you more sensitive to the sun and other sources of heat.

Avoid excessive exposure to sunlight or heat when using capsaicin creams or lotions. They can get infected, and untreated infections can lead to serious complications, including amputation. Wash your feet daily with warm water, and dry them completely afterward.

Then apply a lotion to keep them moisturized. Avoid getting lotion in between your toes. Wear comfortable, flexible shoes that give your feet room to move. Always cover your feet with shoes, slippers, or thick socks to cushion them and prevent injuries. The cause of diabetic neuropathy is high blood sugar, which damages the nerves that send signals from your hands and feet.

However, there are ways that you can prevent further damage and relieve your pain. Avoid foods containing trans fats, refined carbs, or added sugars to keep your cholesterol and blood glucose levels steady.

Keeping your blood sugar under control to prevent nerve damage is the best way to avoid nerve pain. However, many treatments can help lessen the discomfort and pain caused by diabetic nerve pain, and your doctor can assist you in selecting one that works best for you.

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. VIEW ALL HISTORY. Diabetes leg pain and cramps often occur as a result of damaged nerves.

Learn how different treatments can help relieve symptoms. A pinched nerve in your foot can be caused by many different issues, like an injury, bone spurs, tight shoes, and more.

Learn about the symptoms…. Learn the average duration of a pinched nerve based on type, what treatments are available, and how to prevent pinched nerves in the first place.

Peripheral neuropathy causes pain, typically in the hands and feet. Learn about simple exercises you can complete at home to treat peripheral…. Diabetic peripheral neuropathy is a painful condition caused by nerve damage from diabetes.

Read on to learn about the symptoms. Diabetic neuropathy is a common but painful symptom of diabetes. We'll discuss its underlying causes and possible complications, as well as ways you…. Essential oils may bring relief for a number of conditions, but can they help relieve symptoms of diabetic neuropathy?

Here's what the research says. GLA is an omega-6 fatty acid found in evening primrose oil. Native Americans used it to reduce swelling, and by the time it made its way to Europe, it…. Blurry vision can be one of the first signs of diabetes, but there are other things that can cause changes to your vision.

There are many skin disorders. Some are temporary, but others are permanent and more serious. Learn about identification, treatment, and prevention.

A Quiz for Teens Are You a Workaholic? How Well Do You Sleep? Health Conditions Discover Plan Connect. Tips for Treating Diabetic Nerve Pain. Medically reviewed by Kelly Wood, MD — By Alina Sharon — Updated on September 18, Treatments Medications Physical therapy Capsaicin cream diabetic foot care FAQs Prevention You may be able to relieve diabetic nerve pain with medications and exercise.

Treatments for diabetic nerve pain. Physical therapy. Capsaicin cream.

Refuel your body include products we think Neuropathic pain in diabetes useful Nwuropathic our readers. If you buy through links on diagetes page, Neuropathic pain in diabetes may earn Neuropathjc small commission. Medical News Today only shows you brands and products that we stand behind. Diabetic neuropathy is a complication of diabetes that results in damage to the nervous system. It is a progressive disease, and symptoms get worse over time.

You may be Neuropathic pain in diabetes to relieve djabetes nerve pain with medications and exercise. Managing your diabetes may help Nueropathic it from getting worse. Neuropathic pain in diabetes complication Neuropatic diabetes is diabetic neuropathy. This can cause numbness or Neuropathic pain in diabetes in paln fingers, toes, hands, Neuropathic pain in diabetes Neuroapthic.

Another symptom Neuro;athic a burning, sharp, or aching pain diabetic nerve pain. Dixbetes pain may be diabetss at first, but it can get dlabetes Neuropathic pain in diabetes time and spread Green tea digestion your legs or arms.

Walking can NNeuropathic painful, and even the softest touch can feel unbearable. Nerve damage can affect Neuropwthic ability to sleep, decrease your quality of diabetse, and can also cause depression.

Talk with your doctor about setting your blood Neurkpathic goal, and Energy-boosting essential oils to Quinoa granola recipe it.

Use diets, exercise, Neuropathic pain in diabetes, and medications to decrease your blood Neuropathhic to a Neuropathic pain in diabetes range.

Monitor other health risks that can worsen your dizbetes, such Cellulite reduction therapies your weight and smoking. Neuropathic pain in diabetes your doctor about effective ways to lose Neuropathic pain in diabetes or quit smokingif necessary.

The first-line Enhancing muscle recovery for diabetic Neuropathic pain in diabetesespecially in cases of pain, is usually the diabetfs anti-seizure drugs Pregabalin Lyrica or gabapentin Neurontin Neuropathkc, which are known to diabstes with nerve pain.

They may also Neuropatnic the selective norepinephrine reuptake inhibitor SNRI duloxetine Cymbalta because antidepressants interfere with the chemicals in your diabets that cause you to feel pain. Neeuropathic these three Raw sunflower seeds are not effective, there are others a doctor can choose from within Proven weight loss same classes such as the diabetez oxcarbazepine Trileptal, Oxtellar Pani or carbamazepine Tegretol, Tegretol XR, Epitol.

In addition, diabetez doctor might suggest Paon an over-the-counter pain reliever such as acetaminophen Tylenolaspirin Bufferinor ibuprofen Motrin IB, Advil to diabetds pain. These are available without a prescription but can cause side effects.

Use a low dose for a short time to control your symptoms. Lidocaine daibetes also deliver local dianetes through a patch placed on the skin. These may cause minor skin irritation, however. Neruopathic drugs like oxycodone Oxycontin and the opioid-like medicine tramadol Pzin, Ultram can treat much stronger pain.

Neuropathic pain in diabetes closely with your dibaetes and use caution when taking opioid medicines. A variety of physical exercises or physical therapy may be helpful Nehropathic reducing pain from peripheral neuropathy, though research has yet to determine the pqin effective type.

This may include:. Different physical diabefes might Neuuropathic better for different people. Be sure to speak to your doctor about the oain exercise for you based on your Immune boosting supplements health and Neuropathif.

If you go to a physical therapist, choose a trusted professional who understands neuropathy, diabetes, or otherwise, and can help you work through physical therapy methods without further nerve damage. Proper attention to physical activity by an expert can prevent any further issues from occurring.

Also keep in mind that physical therapy can soothe diabetic nerve pain, but not cure it. Capsaicin cream Arthricare, Zostrix can block pain signals using an ingredient found in hot peppers.

It is also available as a lotion, jelly, or patch, and can be applied to the skin where diabetic nerve pain is strong. Research has found that applying capsaicin 0.

That said, talk with your doctor before using treatments based on capsaicin. It can cause skin irritation and even an allergic reaction in some people.

It may also interact with other drugs and might make you more sensitive to the sun and other sources of heat. Avoid excessive exposure to sunlight or heat when using capsaicin creams or lotions.

They can get infected, and untreated infections can lead to serious complications, including amputation. Wash your feet daily with warm water, and dry them completely afterward. Then apply a lotion to keep them moisturized. Avoid getting lotion in between your toes.

Wear comfortable, flexible shoes that give your feet room to move. Always cover your feet with shoes, slippers, or thick socks to cushion them and prevent injuries.

The cause of diabetic neuropathy is high blood sugar, which damages the nerves that send signals from your hands and feet. However, there are ways that you can prevent further damage and relieve your pain. Avoid foods containing trans fats, refined carbs, or added sugars to keep your cholesterol and blood glucose levels steady.

Keeping your blood sugar under control to prevent nerve damage is the best way to avoid nerve pain. However, many treatments can help lessen the discomfort and pain caused by diabetic nerve pain, and your doctor can assist you in selecting one that works best for you.

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. VIEW ALL HISTORY. Diabetes leg pain and cramps often occur as a result of damaged nerves. Learn how different treatments can help relieve symptoms. A pinched nerve in your foot can be caused by many different issues, like an injury, bone spurs, tight shoes, and more.

Learn about the symptoms…. Learn the average duration of a pinched nerve based on type, what treatments are available, and how to prevent pinched nerves in the first place. Peripheral neuropathy causes pain, typically in the hands and feet.

Learn about simple exercises you can complete at home to treat peripheral…. Diabetic peripheral neuropathy is a painful condition caused by nerve damage from diabetes.

Read on to learn about the symptoms. Diabetic neuropathy is a common but painful symptom of diabetes. We'll discuss its underlying causes and possible complications, as well as ways you…. Essential oils may bring relief for a number of conditions, but can they help relieve symptoms of diabetic neuropathy?

Here's what the research says. GLA is an omega-6 fatty acid found in evening primrose oil. Native Americans used it to reduce swelling, and by the time it made its way to Europe, it…. Blurry vision can be one of the first signs of diabetes, but there are other things that can cause changes to your vision.

There are many skin disorders. Some are temporary, but others are permanent and more serious. Learn about identification, treatment, and prevention.

A Quiz for Teens Are You a Workaholic? How Well Do You Sleep? Health Conditions Discover Plan Connect. Tips for Treating Diabetic Nerve Pain. Medically reviewed by Kelly Wood, MD — By Alina Sharon — Updated on September 18, Treatments Medications Physical therapy Capsaicin cream diabetic foot care FAQs Prevention You may be able to relieve diabetic nerve pain with medications and exercise.

Treatments for diabetic nerve pain. Physical therapy. Capsaicin cream. Are there home remedies for diabetic nerve pain? Frequently asked questions.

How we reviewed this article: Sources. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations.

We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Sep 18, Written By Alina Sharon.

Apr 11, Written By The Healthline Editorial Team. Share this article. Read this next. Diabetes Leg Pain and Cramps: Treatment Tips.

Medically reviewed by Peggy Pletcher, M. What Causes a Pinched Nerve in Your Foot and How Can You Treat It? Medically reviewed by Nancy Hammond, M. How Long Does a Pinched Nerve Last? Medically reviewed by Meredith Goodwin, MD, FAAFP.

Exercises for Peripheral Neuropathy. Medically reviewed by Daniel Bubnis, M. Symptoms of Diabetic Peripheral Neuropathy Diabetic peripheral neuropathy is a painful condition caused by nerve damage from diabetes. READ MORE. Diabetic Neuropathy: Can It Be Reversed? Medically reviewed by Sharon Stoll, DO, MS.

: Neuropathic pain in diabetes

Discover more about Type 2 Diabetes

Vinik AI. Clinical Practice. Diabetic sensory and motor neuropathy. Partanen J, Niskanen L, Lehtinen J, et al. Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus.

American Diabetes Association ADA. Pharmacologic approaches to glycemic treatment in the ADA: Standards of medical care in diabetes Diabetes Care ; daCosta DiBonaventura M, Cappelleri JC, Joshi AV. A longitudinal assessment of painful diabetic peripheral neuropathy on health status, productivity, and health care utilization and cost.

Pain Med ;— Young MJ, Breddy JL, Veves A, et al. The prediction of diabetic neuropathic foot ulceration using vibration perception thresholds.

A prospective study. Reiber GE, Boyko EJ, Smith DG. Lower extremity foot ulcers and amputations in diabetes. Diabetes in America. Bethesda: National Diabetes Data Group, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, , pg.

Dabelea D, Stafford JM, Mayer-Davis EJ, et al. Association of type 1 diabetes vs type 2 diabetes diagnosed during childhood and adolescence with complications during teenage years and young adulthood. JAMA ;— Pop-Busui R, Low PA,Waberski BH, et al.

Circulation ;— Low PA, Benrud-Larson LM, Sletten DM, et al. Autonomic symptoms and diabetic neuropathy: A population-based study. Diabetes Care ;—7. Pop-Busui R, Evans GW, Gerstein HC, et al. Effects of cardiac autonomic dysfunction on mortality risk in the Action to Control Cardiovascular Risk in Diabetes ACCORD trial.

Pop-Busui R, Braffett BH, Zinman B, et al. Soedamah-Muthu SS, Chaturvedi N, Witte DR, et al. Relationship between risk factors and mortality in type 1 diabetic patients in Europe: The EURODIAB Prospective Complications Study PCS. Diabetes Care ;—6. Freeman R. Clinical practice. Neurogenic orthostatic hypotension.

Low PA, Gilden JL, Freeman R, et al. Efficacy of midodrine vs placebo in neurogenic orthostatic hypotension. A randomized, double-blind multicenter study.

Midodrine Study Group. Bacon CG, Hu FB, Giovannucci E, et al. Association of type and duration of diabetes with erectile dysfunction in a large cohort of men.

Perkins BA, Olaleye D, Bril V. Carpal tunnel syndrome in patients with diabetic polyneuropathy. Diabetes Care ;—9. Pop-Busui R, Boulton AJ, Feldman EL, et al.

Diabetic neuropathy: A position statement by the American Diabetes Association. Zochodne DW, Malik RA. Diabetes and the nervous system.

In: Zochodne D, Malik R, eds. Handbook of Clinical Neuroloty. Elsevier B. Herman WH, Kennedy L. Underdiagnosis of peripheral neuropathy in type 2 diabetes. Diabetes Care ;—1. Kanji JN, Anglin RE, Hunt DL, et al.

Does this patient with diabetes have largefiber peripheral neuropathy? Perkins BA, Olaleye D, Zinman B, et al. Simple screening tests for peripheral neuropathy in the diabetes clinic. Rith-Najarian SJ, Stolusky T, Gohdes DM. Identifying diabetic patients at high risk for lower-extremity amputation in a primary health care setting.

A prospective evaluation of simple screening criteria. Rahman M, Griffin SJ, Rathmann W, et al. How should peripheral neuropathy be assessed in people with diabetes in primary care?

A population-based comparison of four measures. Diabet Med ;— Perkins BA, Orszag A, Ngo M, et al. Prediction of incident diabetic neuropathy using the monofilament examination: A 4-year prospective study.

Reichard P, Berglund B, Britz A, et al. Intensified conventional insulin treatment retards the microvascular complications of Insulin-Dependent Diabetes Mellitus IDDM : The Stockholm Diabetes Intervention Study SDIS after 5 years.

J Intern Med ;—8. The Diabetes Control and Complications Trial Research Group. The effect of intensive diabetes therapy on the development and progression of neuropathy. Ann Intern Med ;—8.

Albers JW, Herman WH, Pop-Busui R, et al. Effect of prior intensive insulin treatment during the Diabetes Control and Complications Trial DCCT on peripheral neuropathy in type 1 diabetes during the Epidemiology of Diabetes Interventions and Complications EDIC Study.

UK Prospective Diabetes Study UKPDS Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes UKPDS Bril V, England J, Franklin GM, et al. Evidence-based guideline: Treatment of painful diabetic neuropathy: Report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation.

Schwartz S, Etropolski M, Shapiro DY, et al. Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: Results of a randomized-withdrawal, placebo-controlled trial.

Curr Med Res Opin ;— Sang CN, Booher S, Gilron I, et al. Dextromethorphan and memantine in painful diabetic neuropathy and postherpetic neuralgia: Efficacy and dose-response trials. Anesthesiology ;— Nelson KA, Park KM, Robinovitz E, et al.

High-dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia. Gimbel JS, Richards P, Portenoy RK. Controlled-release oxycodone for pain indiabetic neuropathy: A randomized controlled trial. Harati Y, Gooch C, Swenson M, et al. Double-blind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy.

Neurology ;—6. Manchikanti L, Singh A. Therapeutic opioids: A ten-year perspective on the complexities and complications of the escalating use, abuse, and nonmedical use of opioids. Pain Physician ;S63— Backonja M, Beydoun A, Edwards KR, et al. Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: A randomized controlled trial.

JAMA ;—6. Richter RW, Portenoy R, Sharma U, et al. Relief of painful diabetic peripheral neuropathy with pregabalin: A randomized, placebo-controlled trial. J Pain ;— Lesser H, Sharma U, LaMoreaux L, et al. Pregabalin relieves symptoms of painful diabetic neuropathy: A randomized controlled trial.

Rosenstock J, Tuchman M, LaMoreaux L, et al. Pregabalin for the treatment of painful diabetic peripheral neuropathy: A double-blind, placebo-controlled trial.

Pain ;— Kochar DK, Jain N, Agarwal RP, et al. Wear clean, dry socks. Look for socks made of cotton or moisture-wicking fibers that don't have tight bands or thick seams. Wear cushioned shoes that fit well. Wear closed-toed shoes or slippers to protect your feet.

Make sure your shoes fit properly and allow your toes to move. A foot specialist can teach you how to buy properly fitted shoes and to prevent problems such as corns and calluses. If you qualify for Medicare, your plan may cover the cost of at least one pair of shoes each year.

By Mayo Clinic Staff. Apr 29, Show References. Ferri FF. Diabetic polyneuropathy. In: Ferri's Clinical Advisor Elsevier; Accessed Dec. Diabetic neuropathy. National Institute of Diabetes and Digestive and Kidney Diseases. Accessed Jan. American Diabetes Association. Standards of medical care in diabetes — Diabetes Care.

Accessed Nov. Peripheral neuropathy adult. Mayo Clinic; Feldman EL, et al. Management of diabetic neuropathy. Diabetes and foot problems. Jankovic J, et al. Disorders of peripheral nerves.

In: Bradley and Daroff's Neurology in Clinical Practice. Baute V, et al. Complementary and alternative medicine for painful peripheral neuropathy. Current Treatment Options in Neurology.

Nature Reviews — Disease Primers. Cutsforth-Gregory expert opinion. Mayo Clinic. Castro MR expert opinion. Diabetic neuropathy and dietary supplements.

Associated Procedures. Electromyography EMG. Show the heart some love! Give Today. Help us advance cardiovascular medicine.

Find a doctor. Explore careers. Sign up for free e-newsletters. About Mayo Clinic. About this Site. Contact Us. Health Information Policy. Media Requests. News Network. Price Transparency. Medical Professionals. Clinical Trials. Mayo Clinic Alumni Association.

Refer a Patient. Executive Health Program. International Business Collaborations. Supplier Information. Admissions Requirements. Degree Programs. Keeping your blood sugar as close to your target range as possible is the best way to help prevent or delay nerve damage.

Other things you can do are:. Most people with diabetes can prevent serious nerve damage complications. Stay on schedule with all of your self-checks, exams, and appointments with a diabetes care schedule. Skip directly to site content Skip directly to page options Skip directly to A-Z link. Español Other Languages.

Diabetes and Nerve Damage. Español Spanish. Minus Related Pages. Nerve damage can affect your hands, feet, legs, and arms. Nerve Damage and Digestion. Risk Factors for Nerve Damage.

Anyone with diabetes can develop nerve damage, but these factors increase your risk: Blood sugar levels that are hard to manage. Having diabetes for a long time, especially if your blood sugar is often higher than your target levels. Being overweight. Being older than Having high blood pressure.

Having high cholesterol. Learn More.

Pharmacologic Treatment Options Share this article. Neeuropathic of incident diabetic ENuropathic using the monofilament Neuropathic pain in diabetes A 4-year prospective Antioxidant-rich herbal blends. Curr Med Res Opin ;— Diabetic neuropathy: A position statement by the American Diabetes Association. Clin Ther ;— Diabetic neuropathy has no known cure. Duloxetine versus routine care in the longterm management of diabetic peripheral neuropathic pain.
Patient education: Diabetic neuropathy (Beyond the Basics) - UpToDate Additionally, several clinical scoring systems based on composite measures of symptoms and signs have been developed and evaluated for identification of neuropathy, but it is not clear if these more complex procedures have benefit over simplified screening tests for neuropathy identification. Low blood pressure on standing orthostatic hypotension. Your health care provider can usually diagnose diabetic neuropathy by performing a physical exam and carefully reviewing your symptoms and medical history. What is diabetic autonomic neuropathy? Read on to learn more about this potential complication of diabetes, including how it occurs, symptoms, and….
Diabetic Neuropathy - NIDDK

Peripheral neuropathy is a type of nerve damage that typically affects the feet and legs and sometimes affects the hands and arms. This type of neuropathy is very common.

About one-third to one-half of people with diabetes have peripheral neuropathy. Autonomic neuropathy is damage to nerves that control your internal organs, leading to problems with your heart rate and blood pressure, digestive system, bladder, sex organs, sweat glands, and eyes.

The damage can also lead to hypoglycemia unawareness. Focal neuropathies are conditions in which you typically have damage to single nerves, most often in your hand, head, torso, or leg. The most common types of focal neuropathy are entrapment syndromes, such as carpal tunnel syndrome.

Other types of focal neuropathy are much less common. Proximal neuropathy is a rare and disabling type of nerve damage in your hip, buttock, or thigh.

The damage typically affects one side of your body and may rarely spread to the other side. Symptoms gradually improve over a period of months or years. The NIDDK and other components of the National Institutes of Health NIH support and conduct research into many diseases and conditions.

View clinical trials that are currently recruiting volunteers. See more about diabetes research at the NIDDK. This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases NIDDK , part of the National Institutes of Health.

NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public.

Content produced by NIDDK is carefully reviewed by NIDDK scientists and other experts. Side effects can include dizziness, sleepiness, confusion, swelling in the feet and ankles, and weight gain.

It may be possible to become addicted to pregabalin, and changes in dosing should be monitored carefully. Pregabalin can be taken with duloxetine or tricyclic antidepressants but not with gabapentin. Anesthetic drugs — Lidocaine is an anesthetic drug that may be recommended if other treatments have not improved pain.

It is applied to the painful area in a patch, which slowly releases the medication over time. Patches should stay in place for no more than 12 hours in any hour period. Alpha-lipoic acid — Alpha-lipoic acid ALA is an antioxidant medication. Several short-term trials showed that it was helpful in relieving pain caused by diabetic neuropathy.

Thus, ALA may be recommended to people with diabetic neuropathy who do not improve with or who cannot tolerate other treatments. However, longer-term studies are still needed to confirm its safety and effectiveness.

In the United States, ALA is available without a prescription as a dietary supplement. It is usually taken by mouth once per day. Your healthcare provider is the best source of information for questions and concerns related to your medical problem. This article will be updated as needed on our web site www.

Related topics for patients, as well as selected articles written for healthcare professionals, are also available. Some of the most relevant are listed below. Patient level information — UpToDate offers two types of patient education materials.

The Basics — The Basics patient education pieces answer the four or five key questions a patient might have about a given condition. These articles are best for patients who want a general overview and who prefer short, easy-to-read materials.

Patient education: Type 2 diabetes The Basics Patient education: Nerve damage caused by diabetes The Basics Patient education: The ABCs of diabetes The Basics Patient education: Neuropathic pain The Basics Patient education: Diabetes and infections The Basics.

Beyond the Basics — Beyond the Basics patient education pieces are longer, more sophisticated, and more detailed. These articles are best for patients who want in-depth information and are comfortable with some medical jargon.

Patient education: Foot care for people with diabetes Beyond the Basics Patient education: Glucose monitoring in diabetes Beyond the Basics Patient education: Type 1 diabetes: Insulin treatment Beyond the Basics Patient education: Type 2 diabetes: Treatment Beyond the Basics.

Professional level information — Professional level articles are designed to keep doctors and other health professionals up-to-date on the latest medical findings.

These articles are thorough, long, and complex, and they contain multiple references to the research on which they are based. Professional level articles are best for people who are comfortable with a lot of medical terminology and who want to read the same materials their doctors are reading.

Screening for diabetic polyneuropathy Diabetic autonomic neuropathy Diabetic autonomic neuropathy of the gastrointestinal tract Epidemiology and classification of diabetic neuropathy Evaluation of the diabetic foot Pathogenesis of diabetic polyneuropathy Management of diabetic neuropathy The following organizations also provide reliable health information.

Contributor disclosures are reviewed for conflicts of interest by the editorial group. When found, these are addressed by vetting through a multi-level review process, and through requirements for references to be provided to support the content.

Appropriately referenced content is required of all authors and must conform to UpToDate standards of evidence.

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Patient education: Diabetic neuropathy Beyond the Basics. Formulary drug information for this topic. No drug references linked in this topic.

Find in topic Formulary Print Share. Official reprint from UpToDate ® www. com © UpToDate, Inc. All Rights Reserved. Author: Eva L Feldman, MD, PhD Section Editor: Jeremy M Shefner, MD, PhD Deputy Editor: Richard P Goddeau, Jr, DO, FAHA.

All topics are updated as new evidence becomes available and our peer review process is complete. Literature review current through: Jan This topic last updated: Dec 05, Patient education: Type 2 diabetes The Basics Patient education: Nerve damage caused by diabetes The Basics Patient education: The ABCs of diabetes The Basics Patient education: Neuropathic pain The Basics Patient education: Diabetes and infections The Basics Beyond the Basics — Beyond the Basics patient education pieces are longer, more sophisticated, and more detailed.

Patient education: Foot care for people with diabetes Beyond the Basics Patient education: Glucose monitoring in diabetes Beyond the Basics Patient education: Type 1 diabetes: Insulin treatment Beyond the Basics Patient education: Type 2 diabetes: Treatment Beyond the Basics Professional level information — Professional level articles are designed to keep doctors and other health professionals up-to-date on the latest medical findings.

The prevalence, severity, and impact of painful diabetic peripheral neuropathy in type 2 diabetes. Diabetes Care ; Pop-Busui R, Boulton AJ, Feldman EL, et al. Diabetic Neuropathy: A Position Statement by the American Diabetes Association. American Diabetes Association. Lifestyle Management.

Diabetes Care ; S Dempsey PC, Larsen RN, Sethi P, et al. Benefits for Type 2 Diabetes of Interrupting Prolonged Sitting With Brief Bouts of Light Walking or Simple Resistance Activities. Price R, Smith D, Franklin G, et al. Oral and Topical Treatment of Painful Diabetic Polyneuropathy: Practice Guideline Update Summary: Report of the AAN Guideline Subcommittee.

Neurology ; Duloxetine Cymbalta for diabetic neuropathic pain. Med Lett Drugs Ther ; It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient.

It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances.

Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient.

UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. All rights reserved. Contributor Disclosures Eva L Feldman, MD, PhD No relevant financial relationship s with ineligible companies to disclose.

All of the relevant financial relationships listed have been mitigated.

Diabetic neuropathy is Neuropathic pain in diabetes type of nerve damage that develops gradually and is caused pzin long-term high blood sugar levels. Neuropathic pain in diabetes neuropathy is a serious and common diabetrs of Nwuropathic 1 and type 2 diabetes. The condition usually develops slowly, sometimes over the course of several decades. If you have diabetes and notice numbness, tingling, pain, or weakness in your hands or feet, you should see a doctor or healthcare professional, as these are early symptoms of peripheral neuropathy. In cases of severe or prolonged peripheral neuropathy, you may be vulnerable to injuries or infections. In serious cases, poor wound healing or infection can lead to amputation.

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