Gut health and heart health -
In order to use the claim, a food product must contain at least 1g of beta-glucan from barley grain products per serving. Fibre-rich for your gut and with cholesterol-lowering properties for your heart, this once-popular drink is worthy of a comeback.
Experiment by adding other types of fruit, such as berries, oranges, or limes. For an extra kick, boil the barley with some fresh ginger. Add them to your favourite soup or sauce, or save them for breakfast and mix with fruit and yogurt.
Making drastic changes to your diet can have an effect on your gastrointestinal system, and such changes could potentially be dangerous for individuals with certain gastrointestinal or liver diseases. Moderation, even of specific healthy foods, is usually beneficial.
For more information about fibre, the effect of diet on a number of GI and liver conditions, and information on how to find dietitian resources in your region, visit our information centre. You can also contact our office if you wish to receive a specific information package mailed to your home.
Fruit and Veggies A large international study, funded by the Heart and Stroke Foundation of Ontario, and recently published in PLoS Medicine , showed that individuals who carry genes that put them at a higher risk for heart disease than the general population may be able to mitigate that risk by consuming a diet rich in vegetables and fruit.
Psyllium Many individuals who experience bowel irregularities rely on psyllium, a type of soluble dietary fibre found in some foods, especially breakfast cereal, and as a supplement e.
Barley Barley is a fibre-rich whole grain included in many soups, breads, and other foods. Old-Fashioned Fruit Barley Water Ingredients 8 cups water 1 cup washed pearl barley whole lemons tbsp honey, cane sugar, or sweetener of your choice Method Bring water and barley to a boil.
While letting this simmer for min, peel rinds from lemon and add to heat-proof bowl. Strain barley water over rinds into bowl. Add fresh-squeezed lemon juice to bowl and stir. Sweeten to taste. Refrigerate until cold Options Experiment by adding other types of fruit, such as berries, oranges, or limes.
Dietary Changes Making drastic changes to your diet can have an effect on your gastrointestinal system, and such changes could potentially be dangerous for individuals with certain gastrointestinal or liver diseases.
First published in the Inside Tract ® newsletter issue — 1. Do R et al. PLoS Medicine. A certain microbial signature appears to be linked to the development of obesity, identical to IBD. In obese people, the bacterial diversity in their intestines is reduced overall Turnbaugh et al.
Obesity appears to be linked to a modified ratio between Bacteroidetes and Firmicutes in the majority of research in both humans and animal models, with a reduction in Bacteroidetes and an elevation in Firmicutes.
This ratio has been linked to body weight and fat deposition, indicating that obese people have a higher disproportionate ratio of these bacteria Hildebrandt et al.
The number of Bacteroidetes in the intestinal microbiota appears to be relevant in obesity, as obese people on a calorie-restricted diet lose weight and have a higher ratio of Bacteroidetes species in their gut microbiota Ley et al.
Insulin-dependent diabetes mellitus IDDM -related dysbiosis is marked by an increase in Bacteroidetes and Clostridium , as well as a reduction in mucin-degrading bacteria such as Bifidobacteria , Lactobacillus , and Prevotella McLean et al.
Both IDDM and NIDDM are linked to a reduction in total microbial diversity, and a drop in butyrate-producing bacteria and Firmicutes , as well as a disruption in the intestine epithelial barrier and increased intestinal permeability Wen et al.
Elevated lipopolysaccharide LPS translocation and endotoxemia are also reported in NIDDM, which, like obesity, may contribute to reduced inflammation that contributes to the formation of insulin resistance Wang et al.
It is unknown if the unbalanced microbiota is a causal agent or an outcome of diabetes, as it is in other diseases linked with intestinal dysbiosis; nonetheless, several human and animal model studies indicate that changes in the microbiota may predate the onset of IDDM Serino et al.
The microbiota structure of nonobese diabetic NOD mice with diabetes at weaning age differs from the microbiota composition of NOD mice who do not develop diabetes. The frequency of IDDM was also found to be dependent on the overall bacterial environment in which they were housed.
Disease develops in NOD mice in GF settings, but not in mice in specific pathogen-free SPF facilities Nielsen et al. Patients with CRC have a general dysbiosis pattern, which includes a decrease in butyrate-producing bacteria and a rise in the number of multiple potentially dangerous microorganisms.
According to many studies, Proteobacteria , Bifidobacteria , Prevotella , and SCFA production rates have decreased, whilst Firmicutes , Bacteroidetes , Enterobacteriaceae , and Fusobacteria have increased Schulz et al.
Various investigations have also found a rise in two specific bacteria species, Akkermansia muciniphila and Fusobacterium nucleatum , in CRC tissues Castellarin et al. Both of these bacterial species are linked to strong local inflammatory responses, which could be indicative of a high risk of CRC and be involved in inflammation-related disorders.
nucleatum is also linked to an increase in CRC tumors and lymph node cancer. Between patient populations with polyps and those with tumors, substantial variations in mucosal and fecal microbial configurations were found, with the most major changes being Enterobacteriaceae , which was elevated in the mucosa of patients with tumors compared to those with polyps, and Bacteroidetes , which was expanded in CRC tissues with tumor cells compared to those without tumors Sobhani et al.
The gut microbiota is a novel topic of research interest with significant applications in human health with respect to the development of innovative diagnostic and therapeutic tools for preventive and curative outcomes.
Recent molecular and biochemical studies have allowed diverse microorganisms to be detected and categorized and facilitated the analysis of their genomes and metabolites. In particular, genome-scale metabolic models can guide our understanding of the function of individual organisms within the gut microbiota and the role of the microbiota overall since the inter-individual variability of the gut microbiota contributes to different treatment responses and perspectives.
Our mechanistic understanding of how the gut microbiota transforms dietary and endogenous molecules into metabolites shared with peripheral organs and tissues in the host needs substantial expansion. Although the emergence of high-throughput sequencing technologies and bioinformatics over the next decade will inevitably aid in exploring the applicable biological mechanisms, the end of the metabolic pathways sector of the system and the host targets that identify them make up the fascinating puzzle pieces required for the next step in this growing field.
Further mechanistic experiments may result in the development of TMAO as a novel biomarker for the primary prevention of CVD.
This could lead to a change in the conventional risk factors for CVD and modulation therapies directly targeted at the intestinal microbiota. It is expected that these technological advances will promote the transition from correlation experiments to mechanistic insights, resulting in the development of novel diagnostic tests and therapeutics in the near future.
Further research is needed to fully explore the processes underlying host-microbiota interactions to shed light on the biological effects of direct or indirect manipulation of the gut microbiota. MMR, FI, and AAM: Wrote the manuscript; MHR, MSR, MI, and AK: Searched literatures; PS, SM, TE, and MA: Illustrated figures and tables; FW, RI, and TT; Edited the manuscript; AAM and SC: Designed and supervised the review.
All authors finally revised and approved for submission of the final version of the manuscript. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers.
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Hearh bacteria Immune-boosting minerals other microbes in uGt gut healyh you digest food and Heslth support immune, ad, and snd health, among other benefits. Your body is full of trillions of bacteria, viruses and fungi. Gut health and heart health are collectively known as the microbiome. While some bacteria are associated with disease, others are actually extremely important for your immune system, heart, weight and many other aspects of health. Bacteria, viruses, fungi and other microscopic living things are referred to as microorganisms, or microbes, for short. In fact, there are more bacterial cells in your body than human cells. There are roughly 40 trillion bacterial cells in your body and only 30 trillion human cells. Heallth Viome Blog. Leaky Gut. The old saying may ehart true, nealth Elderberry extract for respiratory health way to a man's gealth really is through his stomach. Studies show that gut health and heart health are intricately linked and the key to a healthy heart might lay within your gut. Heart disease is the leading cause of death in the United States. So, it's no surprise that nearly everyone knows someone who's been affected.
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#1 Heart Surgeon: The WORST Food Destroying Your Heart (EAT THIS Instead)Gut health and heart health -
First, bacteria that should be found only in the colon can migrate to the small intestine and cause problems. Second, when specific bacteria are exposed to a high protein diet, it can lead to the production of harmful byproducts, some of which are associated with heart conditions.
And third, when particularly troublesome bacteria leak through the intestinal lining and into the bloodstream, it can lead to widespread systemic inflammation. Almost half 47 percent of all Americans have at least one of the primary risk factors for heart disease — high blood pressure, high cholesterol, or smoking.
The reverse is also true, with chances being higher for having GI issues if you are suffering from a heart condition. In a study published in the journal Digestive Disease and Sciences , patients with SIBO had an 80 percent higher chance of having heart disease.
SIBO has also been associated with deep vein thrombosis, which is when a blood clot forms in one of the deeper veins in the body. LPS is an endotoxin a toxin that is present inside a bacterial cell that is found in the outer membrane of gram-negative bacteria which can cause inflammatory responses throughout the body if given a chance to leave the gut.
These results taken together may suggest a connection between the gut and the heart. The composition and function of the microbiome and produce metabolites that have been associated with an increased risk for developing and having heart disease.
Another harmful bacterial metabolites researchers are investigating is trimethylamine N-oxide or TMAO. When certain gut microbes use choline, found in high quantities in eggs, red meat, poultry, and fish, they can produce trimethylamine TMA. TMA can than be converted into TMAO, which has been linked to plaque formation in arteries atherosclerosis.
In a review published in the Journal of the American Heart Association, 19 studies confirmed a link between elevated TMAO levels and increased risk of heart disease. People who had higher levels of blood serum TMAO were 62 percent more likely to have heart conditions.
High TMAO levels have also been associated with higher mortality rates, independent of other commonly linked risks such as kidney disease, diabetes, and obesity. These findings suggest that evaluating serum levels of TMAO may be an additional factor to consider when gauging someone's risk of developing cardiovascular disease.
A disrupted gut lining is a third potential mechanism by which the gut could be the underlying cause of cardiovascular disease. When the gut lining weakens, it becomes permeable or 'leaky.
This is especially problematic when there are lipopolysaccharides LPS present. When large amounts of LPS enter into circulation, it can lead to systemic inflammation, causing a cluster of symptoms called metabolic endotoxemia. Metabolic endotoxemia can occur when blood serum levels of LPS increase two to three times that of the normal amount.
These elevated LPS levels have been associated with a higher risk of cardiovascular disease and mortality. Another interesting fact is that certain microbes have been found in artery plaques of patients with heart disease. For years, scientists couldn't figure out how they got there. One hypothesis said if you have an impaired gut lining, certain microbes translocate into the bloodstream and relocate in artery walls, causing inflammation and contributing to heart disease.
However, more research is needed to strengthen this connection, and it's one scientists are keeping their eyes on.
The Good News? Short-Chain Fatty Acids for the Win! It's not all bad news when it comes to the gut-heart connection. The good news is there are healthy compounds your gut microbiota produce called short-chain fatty acids that protect the heart. These beneficial short-chain fatty acids, such as butyrate, are almost exclusively made via the gut microbiome.
A review on the gut microbiome and blood pressure concluded that future treatments for cardiovascular disease should aim to treat high blood pressure through modulation of the gut microbiome.
Gut microbiome research takes the idea of eating for a healthy heart to a whole new level. This is excellent news because fighting the number one killer in our country needs to be a top priority. You don't have to wait for research to tell you exactly how to have your microbes work in your favor, you can leverage it right now and take steps to improve the health of your gut microbiome today.
The combination of Veillonella , along with the increased production of gut propionate, has important implications for cardiovascular health by decreasing inflammation, preventing atherosclerotic risk, and improving insulin resistance. The vast amount of evidence emerging in recent decades to further understand the complexity of the gut microbiome not only demonstrates its significance to cardiovascular health 5 but offers insight into prevention and treatment strategies for the ongoing global health problem of CVD.
It is important for cardiovascular nurses to understand the relationship between heart health and gut microbiome, for both informing patient education strategies that are incorporated into clinical care and for future research endeavors.
Additional research is warranted due to the heterogeneity of findings associated with the gut microbiome; 10 however, it is certain that what happens in the gut does not just stay in the gut.
Join PCNA My Classroom Renew GCNLF. Heart Health and the Gut Microbiome. July 12, Elizabeth Moxley. Is Heart Health as Simple as What We Eat?
Four Strategies for Improving the Microbiome 1. Embracing a diet with diverse food sources The diversity of the gut microbiome is linked to the foods we eat—and consumption of a diet with a variety of whole foods, rather than processed or non-whole foods, which can positively impact health.
Ingesting Probiotics Most may be familiar with the role of a probiotic, those living microorganisms that promote the growth of beneficial bacteria in the gut.
Exercise and the Microbiome In addition to diet, improved life expectancy is associated with a strong connection to friends and family, a sense of purpose, a positive outlook on life, and engaging in adequate quantities of physical activity.
Clinical Takeaways for Heart Health and the Gut Microbiome The vast amount of evidence emerging in recent decades to further understand the complexity of the gut microbiome not only demonstrates its significance to cardiovascular health 5 but offers insight into prevention and treatment strategies for the ongoing global health problem of CVD.
References World Health Organization. WHO, National center for chronic disease prevention and health promotion, division for heart disease and stroke prevention. htm Lloyd-Jones DM, Allen NB, Anderson CAM, et al.
Role of the gut microbiota in nutrition and health. Published Jun k Rahman MM, Islam F, -Or-Rashid MH, et al. The gut microbiota microbiome in cardiovascular disease and its therapeutic regulation. Front Cell Infect Microbiol. Gut microbiota in atherosclerosis: focus on trimethylamine N-oxide.
Microbiome connections with host metabolism and habitual diet from 1, deeply phenotyped individuals. Nat Med. Gut microbiome pattern reflects healthy ageing and predicts survival in humans [published correction appears in Nat Metab.
Nat Metab. New insights into gut-bacteria-derived indole and its derivatives in intestinal and liver diseases.
Front Pharmacol. Gut microbially produced indolepropionic acid inhibits atherosclerosis by promoting reverse cholesterol transport and its deficiency is causally related to atherosclerotic cardiovascular disease. Circ Res. Effect of low-fat vs low-carbohydrate diet on month weight loss in overweight adults and the association with genotype pattern or insulin secretion: The DIETFITS randomized clinical trial [published correction appears in JAMA.
A healthy gastrointestinal microbiome is dependent on dietary diversity. Mol Metab. Doi: Zaib S, Hayat A, Khan I. Probiotics and their beneficial health effects [published online ahead of print, Jun 8].
Mini Rev Med Chem. Gut Microbiome: Profound Implications for Diet and Disease.
In the last two decades, healtth Elderberry extract for respiratory health Circadian rhythm sleep-wake been uealth in ad the development Elderberry extract for respiratory health healt gut microbiota and Elderberry extract for respiratory health internal healgh external hralth on the intestine, as well as the risk factors for cardiovascular diseases CVDs such as metabolic syndrome. The intestinal microbiota plays a pivotal role in human health and disease. Recent studies revealed that the gut microbiota can affect the host body. CVDs are a leading cause of morbidity and mortality, and patients favor death over chronic kidney disease. For the function of gut microbiota in the host, molecules have to penetrate the intestinal epithelium or the surface cells of the host. Gut microbiota can utilize trimethylamine, N-oxide, short-chain fatty acids, and primary and secondary bile acid pathways. By affecting these living cells, the gut microbiota can cause heart failure, atherosclerosis, hypertension, myocardial fibrosis, myocardial infarction, and coronary artery disease.
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