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Finding the Best Green Tea and Avoiding DangersGreen tea extract for bone health -
For instance, bisphosphonates may cause odd-fracture and osteonecrosis in jaw 8 , while raloxifene may increase the risk of deep vein thrombosis 9. Public attention regarding the use of herbal medicines is increasing. Numerous studies have explored their pharmacological functions to prevent or treat osteoporosis.
In our previous studies, various Chinese medicines were found to be effective in the prevention and treatment of osteoporosis, including Epimedii Herba, Ligustri Lucidi Fructus and Psoraleae Fructus Besides herbal medicinal products, green tea may represent another possible phyto-candidate for maintaining bone health.
It is one of the most extensively studied plants with well-regarded health benefits and has a long history of consumption with wide safety margins Common green tea polyphenols include - -epigallocatechingallate EGCG , - -epigallocatechin EGC , - -epicatechingallate ECG and - -epicatechin EC Epidemiological evidence has demonstrated an association between tea consumption and prevention of age-related bone loss Furthermore, green tea polyphenols also promoted osteogenesis and inhibited adipocyte formation in human and rat mesenchymal stem cells 17 , Shen et al 19 , 20 reported that green tea polyphenols mitigated bone loss in ovariectomized OVX and chronic inflammation-induced animal models via increasing antioxidant capacity, and decreasing oxidative stress damage and inflammation.
Recently, the authors also found that green tea polyphenols at higher doses suppressed bone turnover in the trabecular and cortical bone of OVX rats and resulted in improved cortical bone structural and biomechanical properties, although it could not prevent the notable cancellous bone loss induced by OVX The aforementioned reports revealed that GTE supplement itself does not effectively prevent the development of osteoporosis compared with antiresorptive drugs, even though positive results had been demonstrated in animal models.
Both phytochemicals and pharmaceutical agents exert individual pharmacological properties. Their combination may complement one another and maximize the ultimate therapeutic effect, while minimizing the adverse effects of pharmaceutical agents by reducing their dosages.
Previously, a group found that a Chinese herbal formula containing Epimedii Herba, Ligustri Lucidi Fructus and Psoraleae Fructus , named ELP synergistically enhanced the therapeutic effect of raloxifene, but not that of alendronate, in rats with osteoporosis The different responses indicated that the interaction between each of the herb-drug combinations is specific and more complex than simply complementing one another.
Considering that GTE and its bioactive polyphenols can promote bone formation while antiresorptive drugs alendronate and raloxifene can inhibit bone resorption, it was hypothesized that the combination of green tea and antiresorptive drugs may exert synergistic effects on inhibiting osteoporosis onset.
Given the increasing popularity of consuming green tea as a health supplement, information on the efficacy and safety of its interaction with various pharmaceuticals is essential. In the present study, it was hypothesized that GTE could synergistically enhance the efficacy of antiresorptive drugs at a low dose, and therefore their clinical dosage could be eventually reduced.
The information generated from this project will provide novel insights for osteoporosis management through a synergistic intervention between herbal health supplements and conventional pharmacotherapy.
The present study aimed to investigate the synergistic effects of GTE and antiresorptive drugs on bone protection in an OVX rat model in relation to BMD and bone microarchitecture. All chemicals were purchased from Sigma-Aldrich Merck KGaA unless otherwise specified.
Alendronate sodium and raloxifene hydrochloride were purchased from Merck KGaA and Eli Lilly and Company, respectively. The herbarium voucher specimen reference no.
GTE of the tested herb was deposited in the Institute of Chinese Medicine, The Chinese University of Hong Kong. For GTE preparation, the tea leaves g were brewed with 1 l hot distilled water 80˚C 3 times 15 min each. The infusion was then cooled to room temperature and filtered through cellulose filter paper 0.
The filtrate was concentrated using a vacuum rotary evaporator, followed by freeze-drying at ˚C overnight to produce the GTE powder. The chemical composition of GTE was analyzed using high-performance liquid chromatography Fig. S1 and the method is described in Data S1.
They were maintained on standard rodent chow that contained 0. Animals in the sham group underwent the same surgical procedure but without the ligation of the oviducts or excision of the ovaries. Animal experimentation ethics approval for this study was obtained from the Animal Experimental Ethics Committee of The Chinese University of Hong Kong approval no.
Three weeks after the surgical operation, osteoporosis was developed in this animal model according to our previous study, in which a significant decrease in total BMD in lumbar spine, femur and tibia was induced Next, animals received GTE and two antiresorptive drugs [alendronate A and raloxifene R ] via oral administration daily using gavage for 4 weeks Table I.
GTE and both drugs were dissolved in distilled water. The OVX and sham groups were administered the same volume 2 ml of distilled water. Body weight and BMD of the animals were measured weekly. At the end of study, blood samples were obtained from the abdominal inferior vena cava of the animals after they had been anaesthetized as mentioned above, and the animals were then euthanized immediately via cervical dislocation.
The confirmation of death was assessed via direct cardiac palpation to confirm lack of cardiac activity. Femora were then harvested for microarchitectural analyses. Uteruses were also harvested and weighed immediately data not shown.
Completed ovariectomy was confirmed at necropsy by marked atrophy of the uterine horns and absence of ovarian tissue. Group 1 was sham operated. The other 12 groups of rats were OVX. High dose of alendronate [group 7, A H , 0. For the remaining groups, combined treatment of GTE with high or low dose of alendronate or raloxifene was administered to study the interactions between GTE and various drug combinations.
From the start of the treatment day 0 , changes in BMD at lumbar vertebra L5 , proximal tibial metaphyses and distal femoral metaphyses of the rats were monitored weekly for 4 weeks using peripheral quantitative computed tomography pQCT; XCT; Stratec Medizintechnik GmbH.
Briefly, the animals were anesthetized as described in the ovariectomy section. They were then placed and secured on a custom-made translucent plastic holder. Lumbar spine L5 , right proximal tibia and distal femurs were scanned under the built-in research mode of pQCT. Total BMD BMD including both cortical and trabecular areas was generated and presented.
The microarchitecture of the left distal femur was analyzed using micro-CT Micro CT 40; Scanco Medical AG. Briefly, the femur was aligned perpendicularly to the scanning axis.
The scanning was conducted at 55 kVp and µA with a resolution of 16 µm per voxel. The trabecular bone in the distal femur was identified using drawn contour at each two-dimensional section semi-automatically. The volume of interest VOI was determined within 50 continuous slices. The microarchitectural parameters of the VOI were obtained via three-dimensional reconstructed images using the built-in software of the micro-CT workstation.
N , trabecular thickness Tb. Th and trabecular plate separation Tb. Sp ] were analyzed. Serum was obtained by centrifuging the blood samples at 1, x g for 20 min at 4˚C, and was stored at ˚C until analysis. Osteocalcin OC is secreted solely by osteoblasts, and its concentration in serum is often used as a measure of bone formation.
C-terminal telopeptide CTX is released into the bloodstream during bone resorption and hence can serve as a specific marker for the degradation of mature type I collagen in bone. In addition, tartrate-resistant acid phosphatase 5b TRAcP 5b is a specific marker of osteoclasts, which are known to mediate bone resorption Hence, TRAcP 5b can also serve as an indicator of the extent of bone resorption.
SB-TR and Serum CrossLaps ® CTX-I cat. ACF1 , respectively, Immunodiagnostic Systems Holdings], according to the manufacturer's instructions. A standard curve was generated from each kit, and the concentration of each bone turnover marker was calculated from the corresponding standard curve.
The groups with alendronate and raloxifene were compared separately. All the covariates were adjusted for statistical analysis, which was performed using the GraphPad Prism version 6. Data are expressed as the mean ± standard deviation.
BMD has been long regarded as a surrogate measure of bone strength. The present study revealed that oral GTE treatment for 4 weeks resulted in a higher BMD on the bone compared with that of OVX Fig. GTE oral administration increased BMD in a dose-dependent manner in proximal tibia.
Effect of GTE at different concentrations on the bone of osteoporotic rat after 4 weeks of treatment. N, Tb. Th and Tb. Sp at the metaphysis of the distal femur measured by micro-CT. OVX without treatment. N, trabecular number; Tb. Th, trabecular thickness; Tb. Sp, trabecular separation; Trab, trabecular; BMD, bone mineral density.
In the sham group, an overall increase in total BMD was observed in lumbar spine, distal femur and proximal tibia Fig.
The effect of ovariectomy on the reduction of total BMD was prominent in these regions of the OVX group. Total BMD of the OVX group continued to decrease throughout the 4 weeks of treatment, particularly in proximal tibia Fig.
Those 11 treatment groups had a significantly higher BMD at the lumbar spine than the OVX group from week 2 onwards. Regarding treatment with the antiresorptive drug alone, alendronate exhibited a dose-dependent protective effect on BMD in both femur and tibia Fig.
Both A H and R H significantly increased total BMD in all bone regions compared with the findings in the OVX group. The protective effect of alendronate was higher than that of raloxifene. Compared with the baseline value, total BMD in femur and tibia of rats treated with A H was significantly higher at weeks 3 and 4 [ Changes of total BMD at different regions of rats co-treated with GTE and antiresorptive drugs.
Mean of percentage changes from baseline Week 0 of the total BMD at lumbar spine, proximal tibia and distal femur co-treated with A A and B R.
The error bar represents the ±SD. Two-way ANOVA followed by Bonferroni's correction. BMD, bone mineral density; GTE, green tea extract; OVC, ovariectomized; ns, not significant; L, low dose; H, high dose; A, alendronate; R, raloxifene.
In the combination studies, the data demonstrated that GTE worked synergistically with alendronate in increasing BMD. Compared with the findings in the OVX group, co-treatment with GTE and A L significantly increased total BMD in all bone regions at weeks 3 and 4.
However, A L alone did not exhibit a significant effect in reducing total BMD in distal femur. GTE was also found to enhance the effect of A H on total BMD compared with that of A H , and significant differences were found in spine weeks 3 and 4 and femur week 4 Fig.
Overall, co-treatment of GTE and A L was found to be the most effective combination to reduce total BMD loss among the groups. Notably, the combination of GTE and raloxifene did not result in any synergistic effect on the reduction of total BMD loss, regardless of the concentrations of raloxifene Fig.
To further evaluate the impact of different GTE-drug combinations on the quality of trabecular bone, bone microarchitectural properties of the distal femur were analyzed. All the GTE treatment groups showed improvements in the microarchitectural properties of the trabecular bone over the OVX group.
Th compared with the OVX group. N and Tb. Th, whereas it decreased the Tb. Sp, compared with the OVX group Fig.
Both alendronate and raloxifene treatment resulted in an improvement in the bone microarchitectural properties at the distal femur Fig. Th, and a decreasing trend in Tb.
Sp, as the dosage of alendronate increased [A H compared with A L ] Fig. Notably, the combination of GTE and A L or R L significantly increased Tb. N compared with the findings in the OVX group. This osteo-protective effect could not be observed either in GTE, A L or R L alone.
Rats treated with low-dose alendronate and GTE simultaneously further increased their Tb. N compared with that of rats treated with low-dose alendronate alone. The effect of low-dose alendronate plus GTE on bone microarchitecture was comparable to that of treatment with high-dose alendronate alone, but no statistically significant difference was observed.
Difference in microarchitectural properties at the distal femur of rats co-treated with GTE and antiresorptive drugs. Th , and trabecular separation Tb. Sp after 4 weeks of co-treatment with A A and B R. Sp, trabecular separation; L, low dose; H, high dose; A, alendronate; R, raloxifene.
A prominent synergistic protective effect on bones was observed following treatment with GTE and alendronate. Therefore, measurement of serum biochemical markers in the groups treated with GTE and alendronate alone or in combination at various concentrations was conducted.
After 4 weeks of treatment, the serum CTX concentration was reduced effectively by alendronate at both low 0. GTE alone significantly increased the serum OC level, which was similar to the effect of alendronate at both low and high concentrations.
Nevertheless, no synergistic effect was observed when GTE was co-administered with alendronate. GTE nor alendronate at both concentrations alone could significantly reduce the serum TRAcP 5b level compared with the findings in the OVX group.
Notably, the combination of GTE and alendronate at low concentration synergistically decreased the TRAcP 5b level significantly when compared with the effect of alendronate at low level alone. Collectively, these findings indicated an important role of GTE in reinforcing the effects of alendronate on enhancing bone formation and inhibiting bone resorption.
GTE, green tea extract; OVX, ovariectomized; L, low dose; H, high dose; A, alendronate; OC, osteocalcin CTX, C-terminal telopeptide; TRAcP 5b, tartrate-resistant acid phosphatase 5b.
In the present study, a synergistic effect between GTE and alendronate on reduction of osteoporotic bone loss caused by ovariectomy was identified. Particularly, GTE was demonstrated to enhance the effect of a low dose of alendronate on inhibiting bone resorption, as indicated by a decrease in TRAcP 5b level.
Regarding the antiresorptive drug raloxifene, it was observed that the addition of GTE to raloxifene at all concentrations prevented BMD loss at lumbar spine, distal femur and proximal tibia, and improved the bone microarchitectural properties in the femur compared with the findings in the OVX group.
Compared with the effects of treatment with raloxifene alone, however, the presence of GTE did not result in significant differences in any of the parameters evaluated.
Notably, our group previously observed that the extract of a Chinese herbal formula ELP worked synergistically with raloxifene in increasing the BMD of osteopenic bone in an OVX rat model This synergistic effect was further substantiated by bone microarchitecture analysis.
The discrepancy between the results of the two studies may be due to the different compositions of the two herbal extracts. The main composition of green tea is tea polyphenols, which is absent in ELP. In the present study, the composition of the tea polyphenols in the GTE was similar to that of the green tea polyphenols in previous studies conducted by Shen et al 20 , In all of these studies, the most abundant catechin was EGCG, followed by ECG and EGC.
A small quantity of catechin was also identified. On the other hand, some estrogenic compounds in ELP may work synergistically with raloxifene to result in osteo-protection. Raloxifene is an oral selective estrogen receptor modulator that has estrogenic actions on inhibiting bone resorption 5 , When ELP is combined with raloxifene, the stimulation of osteoblasts by ELP may have an additive effect in the anti-osteoclastic action of raloxifene.
Besides, the difference in treatment period and osteoporotic conditions between the two studies may also attribute to the discrepancy in the results. The treatment period of the ELP study was 8 weeks, compared with the 4-week GTE treatment period in the current study.
It was also the effective dose to improve femoral BMD of OVX rats. They may have different chemical composition different concentrations of alkaloids and catechins ; ii Extraction method: Wu et al extracted g of green tea twice using 1, ml of water each time 1.
This difference may alter the concentrations of chemical composition of GTE; iii species of animal model; and iv treatment protocol-Wu et al started the GTE treatment after 2 weeks of the OVX and the treatment this lasted for 13 weeks. However, the present study started the GTE treatment after 3 weeks of the OVX and the treatment period was only 4 weeks.
This meant that osteoporosis had reached a more severe condition than Wu et al while the treatment period was shorted than the duration selected. They may advise drinking less than milligrams of caffeine. Too much green tea may raise the risk of birth defects, and caffeine may pass through breast milk.
High doses of green tea may interact with certain medications, including those that treat heart problems and high blood pressure. Although rare, research has linked liver problems to tea products, especially green tea extract.
Whether you sip your green tea iced or hot, here are a few tips to keep in mind:. The caffeine in green tea is a stimulant, increasing alertness and keeping you awake. You may drink a cup of green tea in the morning as a substitute for coffee for an energy boost.
In contrast, caffeine generally stays in your body for up to six hours, so avoid green tea too close to bedtime. Consider pairing a cup of green tea with food. Caffeine increases the amount of acid in your stomach, which may cause an upset stomach and heartburn.
There are several types of green tea, including:. One of the most common types of green tea is Sencha, typically made in Japan. Sencha includes Bancha and Matcha. Bencha has less caffeine and L-theanine, while Matcha has the highest amounts.
Green tea is a staple in many cultures and may offer essential benefits, like protecting your bone, brain, and heart health. Even so, green tea may be risky for people with caffeine sensitivity or who take certain medications.
Ask a healthcare provider or dietitian for guidance about how green tea may impact your health goals if you do not currently drink it and are unsure if it's right for you. You may be able to reap the possible benefits of green tea by consuming it daily. Other factors like eating a balanced diet, getting enough sleep , managing stress, and regularly exercising are essential to good health.
Ensure that you are practicing healthy lifestyle changes in addition to drinking green tea daily. It's safe to drink eight cups of green tea daily.
Each eight-ounce cup of green tea has about 30—50 milligrams of caffeine. The Food and Drug Administration advises not drinking more than milligrams of caffeine daily. Green tea products may add caffeine during manufacturing and only list the amount added.
There's not enough evidence about the optimal amount of green tea to reap the most benefits. Manufacturing typically destroys antioxidants. As a result, bottled green tea drinks, decaf green tea, and green tea powders may lack antioxidants. Instead, try limiting the amount of added sugars, like honey and stevia, and steeping your green tea at home to get the most benefits.
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Bome © Exrract et al. This is an open access Parental involvement in youth sports distributed under the extrat of Creative Gteen Attribution License. Osteoporosis is Green tea extract for bone health major health concern Green tea extract for bone health the world. It primarily affects the elderly, particularly postmenopausal women 1. Osteoporosis is characterized by low bone mass and deterioration of bone microarchitecture 2. In addition, it contributes to an increase in bone fragility, resulting in disability and mortality of the elderly 3. The worldwide incidence of osteoporotic hip fracture is ~1.New research from Hong Kong found that green Greeone of the most popular drinks jealth the Green tea extract for bone health, may benefit bone Pomegranate Seed Oil Preventing fatigue through diet the researchers suggest it has the potential to help prevent and treat osteoporosis and other bone diseases suffered by extractt of people worldwide.
The study was the work of Dr Ping Bbone Leung and colleagues from blne Institute of Chinese Ehalth Pomegranate Seed Oil the Chinese University of Hong Kong, and you can read about Glutathione IV therapy in the Journal of Agricultural and Food Chemistry where a web version Pomegranate Seed Oil last month.
Other studies have already suggested that chemicals Greenn green tea benefit health in many ways, etract example rea preventing cancer and heart tae Green tea extract for bone health, but Bons is the Endurance recovery foods study to pinpoint which of those chemicals may also improve bone health by stimulating formation and bine the breakdown of hewlth.
In humans, Green tea extract for bone health in Hydration strategies organisms, bone is not Pomegranate Seed Oil hralth tissue but a living dynamic fpr system that relies on a delicately maintained balance between hwalth formation and bone resorption.
Cells called osteoblasts Cholesterol-lowering cooking tips bone while Green tea extract for bone health called osteoclasts resorb it. For the tez, the researchers exposed a group of cultured rat osteoblast-like hexlth to healtj catechin chemicals for several healfh.
The chemicals were epigallocatechin EGCgallocatechin GCand gallocatechin etxract GCGall main components of green tea. They found that boone catechin in particular, EGC, Green tea extract for bone health, stimulated the action of a key enzyme that promotes bone growth by up to 79 per cent.
The effect of boosting EGC also increased the level of bone mineralization in the cells, which strengthens bones. They also found that EGC weakened the activity of osteoclasts, tipping the delicate bone metabolism balance away from resorption to formation.
The researchers also noted that the catechins did not appear to cause toxic effects in the bone cells. Osteoporosis is a condition where the density and quality of bone is reduced, increasing the risk of fracture.
According to the International Osteoporosis Foundation, for the yearthere were an estimated 9 million new osteoporotic fractures worldwide, of which 1.
Europe and the Americas accounted for just over half of all these fractures, while most of the remainder were in the Western Pacific region and Southeast Asia. Although usually affecting women more often than men, in China there is a higher incidence of hip fractures in men than women.
Food Chem, 57 16pp Publication Date Web : August 4, Article DOI: There is not one type of doctor that treats osteoporosis, as professionals of different medical disciplines can help manage the condition. Learn more…. Osteoporosis is not a disability on its own, but chronic pain or recurring fractures can result in a disability qualification if they affect a….
There are many safe treatment options for people with osteoporosis. Bisphosphonate drugs can preserve bone strength and prevent fractures. Screening for osteoporosis is usually safe and painless.
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: Green tea extract for bone health| 1. Improves brain functioning | You are using a browser version with limited support for CSS. Discussion We present the rationale, design, and methodology of a placebo-controlled randomized trial to investigate a new complementary and alternative medicine strategy featuring a dietary supplement and a mind-body exercise for alleviating bone loss in osteopenic postmenopausal women. Urinary and serum GTP concentrations were determined at baseline, 4, 12, and 24 weeks. Article CAS PubMed Google Scholar Isomura H, Fujie K, Shibata K, Inoue N, Iizuka T, Takebe G, Takahashi K, Nishihira J, Izumi H, Sakamoto W: Bone metabolism and oxidative stress in postmenopausal rats with iron overload. Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: A randomized controlled trial. Full size image. |
| We Care About Your Privacy | Figure tda. Most of the participants preferred fermented tea, were aged 50 tew Green tea extract for bone health years, resided in urban areas, and attended high school. Article CAS PubMed Google Scholar Siris, E. They may advise drinking less than milligrams of caffeine. Daniells, S. Unno K, Nakamura Y. |
| Latest news | The limits of detection were 0. The levels of glucuronidated or sulfated GTP or methylated GTP were calculated by subtraction of free GTP levels from corresponding digestions. The four forms of GTP were pooled as a total for calculation of conjugation percentiles. Due to the longitudinal design of the proposed study, a model of repeated measurements with random effect error terms was used. Statistical software SAS was employed to conduct the analyses, controlling for the within subject correlation. First, the measurements were compared across the 4 groups at the baseline. In addition, participant characteristics were compared to detect whether participants in these four groups were different in certain characteristics. Second, the changes in the measurements from baseline to the follow-ups were calculated for each group. We then tested whether these changes were statistically significant. Time-dependent trends, if any, were identified. For between-group differences, a two-way ANCOVA TC and GTP was conducted and controlled for within-subject correlation. To control for the effect of age, body mass index, BMD, and other covariates i. Third, the characteristics of participants who dropped out were compared with those of the participants who stayed for the entire study period, in order to detect potential biases. We have presented the rationale, design, and methodology of a placebo-controlled randomized trial, with quantitative studies, to investigate a new complementary and alternative medicine strategy featuring a dietary supplement and a mind-body exercise for alleviating bone loss in postmenopausal women with low bone mass. The results of this research will be presented as soon as they are available. NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy: Osteoporosis prevention, diagnosis, and therapy. Article Google Scholar. 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The contents of this manuscript are solely the responsibility of the authors and do not necessarily represent the official views of the NCCAM or the National Insititues of Heatlh. We would like to thank Dr. Jay Magaziner Univeristy of Maryland, MD and Dr. Bahram H. Arjmandi Floride State University, FL for their advice. Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. Laura W Bush Institute for Women's Health, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. Department of Laboratory Science and Primary Care, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. Department of Cell Physiology and Molecular Biophysics, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. Department of Nutrition, Texas Tech University, Lubbock, Texas, USA. Department of Mechanical Engineering, Texas Tech University, Lubbock, Texas, USA. Department of Health, Exercise, and Sport Sciences, Texas Tech University, Lubbock, Texas, USA. Graduate Healthcare Engineering Option, Texas Tech University, Lubbock, Texas, USA. Applied Bench Core Laboratory, Winthrop-University Hospital, Mineola, New York, USA. Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. Department Family and Community Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. Department of Environmental Health Science, University of Georgia, Athens, Georgia, USA. You can also search for this author in PubMed Google Scholar. Correspondence to Chwan-Li Shen. CLS obtained funding for the study. CLS, MCC, JKY, CKF, KTX, BCP, and JSW designed this trial. CLS wrote the first draft of the manuscript and the rest of coauthors participated in the revision of subsequent dra. All authors approved the final version of the manuscript. None of the authors declared any conflicts of financial interest. This article is published under license to BioMed Central Ltd. Reprints and permissions. Shen, CL. et al. Green tea polyphenols and Tai Chi for bone health: Designing a placebo-controlled randomized trial. BMC Musculoskelet Disord 10 , Download citation. Received : 05 August Accepted : 04 September Published : 04 September Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative. Skip to main content. Search all BMC articles Search. Download PDF. Abstract Background Osteoporosis is a major health problem in postmenopausal women. Discussion We present the rationale, design, and methodology of a placebo-controlled randomized trial to investigate a new complementary and alternative medicine strategy featuring a dietary supplement and a mind-body exercise for alleviating bone loss in osteopenic postmenopausal women. Trial registration ClinicalTrials. gov identifier: NCT Background Osteoporosis is a degenerative bone disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures, especially of the hip, spine, and wrist [ 1 ]. Figure 1. Study flow chart. Full size image. Discussion We have presented the rationale, design, and methodology of a placebo-controlled randomized trial, with quantitative studies, to investigate a new complementary and alternative medicine strategy featuring a dietary supplement and a mind-body exercise for alleviating bone loss in postmenopausal women with low bone mass. 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CAS PubMed Google Scholar Vestergaard P, Hermann AP, Gram J, Jensen LB, Eiken P, Abrahamsen B, Brot C, Kolthoff N, Sørensen OH, Beck Nielsen H, Pors Nielsen S, Charles P, Mosekilde L: Evaluation of methods for prediction of bone mineral density by clinical and biochemical variables in perimenopausal women. Article CAS PubMed Google Scholar Wu CH, Yang YC, Yao WJ, Lu FH, Wu JS, Chang CJ: Epidemiological evidence of increased bone mineral density in habitual tea drinkers. Article PubMed Google Scholar Johnell O, Gullberg B, Kanis JA, Allander E, Elffors L, Dequeker J, Dilsen G, Gennari C, Lopes Vaz A, Lyritis G: Risk factors for hip fracture in European women: the MEDOS Study. Article CAS PubMed Google Scholar Kanis JA, Johnell O, Oden A, Jonsson B, De Laet C, Dawson A: Risk of hip fracture according to the world health organization criteria for osteopenia and osteoporosis. Article CAS PubMed Google Scholar Schneider C, Segre T: Green tea: potential health benefits. PubMed Google Scholar Cabrera C, Artacho R, Giménez R: Beneficial effects of green tea--a review. Ko, K. Lau, W. Choy, P. Show more. Content provided by LEHVOSS Nutrition Jan White Paper. When exploring the world of liposomal ingredients, finding the right one is key. Kaneka Ubiquinol Recorded the Nov Webinar. In partnership with Kaneka Corporation, Dr Leah Hechtman PhD will delve into the science of the antioxidant ubiquinol and its profound impact on mitochondrial Content provided by Gencor Oct Product Brochure. In a recent clinical trial backing its ingredient Libifem® for improved muscle strength, power, endurance and body composition with a females-only popluation Content provided by LEHVOSS Nutrition Oct Product Brochure. OptiMSM® is the industry leading brand of MSM that has been a pioneer in the field of sulphur nutrition for over 30 years. CONTINUE TO SITE Or wait Discover Maximum Nutrient Delivery. |
| Green Tea May Benefit Bone Health | Research has found that drinking green tea may Quenching vitamin-infused water one way to help prevent your risk rea stroke. Femora were then Green tea extract for bone health Greeb microarchitectural analyses. Grden 1. Pomegranate Seed Oil may have different chemical composition different concentrations of alkaloids and catechins ; ii Extraction method: Wu et al extracted g of green tea twice using 1, ml of water each time 1. Some experts suspect that the lifestyle habits of green tea drinkers, such as eating a balanced diet, may influence stroke risk. Thand trabecular separation Tb. |
| Introduction | The main composition of green tea is tea polyphenols, which is absent in ELP. Can green tea preparations help with weight loss? The discrepancy between the results of the two studies may be due to the different compositions of the two herbal extracts. Xu R, Yang K, Ding J, et al. J Nutr. They may have different chemical composition different concentrations of alkaloids and catechins ; ii Extraction method: Wu et al extracted g of green tea twice using 1, ml of water each time 1. |
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