Make sure to take your medicines exactly as prescribed, Red pepper shrimp follow researchh healthy-lifestyle plan. The NHLBI Heart health research Hsart research that helped shape the understanding of risk factors for cardiovascular disease in middle-aged Americans. Vaccines help protect against infectious diseases. She helped establish the Canadian Post-Pregnancy Clinical Network, which connects over 20 postpartum prevention clinics across the country. Products and Services Blood Pressure Monitors at Mayo Clinic Store A Book: Live Younger Longer A Book: Future Care.

Heart health research -

Funding for training and early-career investigators represents a substantial portion of the millions that we invest into research each year. That commitment has brought results. The many AHA-funded discoveries include the first implantable pacemakers, the first artificial heart valve, CPR techniques and cholesterol-lowering medications.

Tackling Heart And Brain Challenges As a researcher, peer review volunteer or a donor, you can join the American Heart Association as we fight for a world free of heart disease and stroke. Learn more: Precision Medicine Platform.

Learn more about AHA Research. Learn more about Peer Review. Donate now. For researchers. AHA Research Highlights Research breakthroughs funded by the AHA over the years Research Milestones.

Correcting heart defects in newborns In , Dr. Drug found to lower cholesterol Research by Dr. It provides high-resolution images that help physicians determine the right stent size to use and where and how to place it.

The ILUMIEN IV study compared OCT-guided PCI to angiography-guided PCI in 2, people with diabetes or high-risk coronary lesions at 80 sites in 18 countries.

OCT guidance resulted in a larger minimum stent area — the area opened up so blood could flow more freely — and appeared to be safe. Both methods were equally effective at preventing death, heart attacks or the need for further revascularization over two years of follow-up.

The OCTOBER trial compared these two methods for placing stents in 1, people in 38 centers in Europe who had complex coronary artery bifurcation lesions — plaque build-up in areas where arteries branch that are difficult to see. Over two years of follow-up, people who had OCT-guided PCI had fewer adverse major cardiac events and deaths than those whose stents were placed using angiography guidance.

There was a similar rate of complications for both groups. A third NEJM study — RENOVATE-COMPLEX-PCI — compared intravascular imaging-guided PCI either ultrasonography or OCT to angiography-guided PCI for 1, patients in South Korea with complex coronary artery lesions.

Over two years of follow-up, people treated with either type of intravascular imaging-guided PCI experienced fewer heart-related deaths, heart attacks or need for further revascularization than those whose PCI was guided by angiography.

Complication rates were similar for both groups. The OCTIVUS randomized, clinical trial, published in Circulation, compared the safety and effectiveness of the two types of intravascular image guidance in 2, patients with significant coronary artery lesions and found both were equally safe and effective.

Together, these studies illustrate the complexity of coronary artery disease and the promise of more advanced guidance technologies for tailoring treatment to improve patient outcomes. People with atrial fibrillation, also known as AFib, experience rapid and irregular heartbeats in the upper chamber of the heart.

This can slow blood flow, causing blood to collect in the heart, where it forms clots that may travel to the brain and cause a stroke. People with AFib may be treated with Direct-Acting Oral Anticoagulants DOAC — quick-acting blood thinners that help to prevent strokes from occurring.

But how soon to begin this medication after a stroke in a person with AFib was unclear. Doing so too early could increase the risk of brain bleeds, while doing so later could raise the risk of having a second stroke.

Under current clinical practice, treatment is typically delayed at least a few days. A new study , published in the New England Journal of Medicine, suggested treatment with DOACs might safely begin much sooner.

Researchers randomly assigned 2, people with AFib from stroke centers in Europe, the Middle East and Asia to receive early anti-coagulation treatment within 48 hours of a minor or moderate stroke and on day six or seven following a major stroke or later anti-coagulation treatment on day three or four following a minor stroke, day six or seven following a moderate stroke and on day 12, 13 or 14 following a major stroke.

How researchers measured stroke severity differed from previous investigations. The standard practice is to use a score based on the location and size of an infarct, or dead tissue in the brain caused by the loss of blood supply.

In this trial, researchers used CT or MRI scans to measure the size of infarcts. They concluded that this method allowed them to better identify people who could benefit from earlier use of DOACs. While outcomes between the two groups were not substantially different, overall, the findings showed earlier treatment resulted in a lower risk for recurrent strokes and slightly lower risk for bleeding outside the brain in the month following a stroke, even in those who had major strokes.

The incidence of bleeding inside the brain was low in both groups. The trial was not designed to test whether earlier treatment was better than later treatment, but to help health care providers estimate possible outcomes. Obesity rates in the U. have tripled over the last 50 years, contributing to the increase in a wide range of health problems, including type 2 diabetes and cardiovascular disease.

This has led to the development of medications to manage weight and lower blood glucose levels. Glucose-lowering drugs have been shown to reduce major cardiovascular events and outcomes for people with diabetes, who are at high risk for heart attack, stroke, heart failure and cardiovascular-related death.

A review paper in Circulation summarized how this class of drugs has changed the landscape for people with type 2 diabetes, offering heart-health protection regardless of how well glucose levels are being controlled.

Two studies suggested semaglutide, a medication approved for long-term weight management, could help obese people lower their risk for heart problems and reduce heart failure-related symptoms. This condition has been increasing in prevalence, often accompanied by symptoms such as shortness of breath, fatigue and decreased tolerance for exercise, especially in people who are obese.

But no therapies have been approved to treat this group of patients. A paper in the New England Journal of Medicine suggests semaglutide can improve quality of life for patients with heart failure. Among patients given once-weekly injections of semaglutide or placebo for one year, semaglutide led to greater reductions in heart failure-related symptoms, greater improvements in the ability to exercise and greater weight loss.

Semaglutide had already been shown to lower the risk for heart problems in people with diabetes. Among 17, people 45 and older, they found the drug superior to placebo in reducing cardiovascular-related death, nonfatal heart attacks and nonfatal strokes.

For example, Black adults and people in rural areas have disproportionate rates of heart disease and are more likely to die from it. A growing body of research highlights how social determinants of health SDOH play a role in these disparities.

These social factors can include where a person lives, access to health care, transportation, healthy foods and safe places to stay physically active.

The stress of structural racism and other types of discrimination can also play a role, as can whether they live in low-income neighborhoods or have clean air or water.

A longitudinal analysis in the Journal of the American Heart Association used federal SDOH data, coupled with county-level cardiovascular disease mortality data, to analyze which factors were most strongly linked to heart-related death rates.

They noted that while county-level cardiovascular death rates were declining in the decade studied, they remained higher in rural counties and in counties with a higher percentage of Black residents. Cardiovascular death rates were most strongly linked to income status, along with access to healthy foods and housing, suggesting that addressing these issues could save lives.

Another way race affects cardiovascular mortality has to do with how likely people are to receive help when they need it, such as when someone experiences sudden cardiac arrest outside a hospital setting. People who experience an out-of-hospital cardiac arrest — when the heart suddenly stops — are nearly twice as likely to survive if a bystander performs CPR while they wait for emergency medical personnel to arrive.

The disparity exists whether the cardiac arrest is witnessed at home or out in public, regardless of the racial or ethnic make-up or income level of people in the neighborhood where it occurs.

While CPR training is less common in Black communities than in white communities, implicit biases also appear to play a role.

Researchers have long known that a healthy diet plays a critical role in good health. The USDA publishes dietary guidelines to encourage people to follow healthy eating patterns, based on the latest nutrition science.

And we must empower those who live with it. Funding Opportunities We take risks on high-reward projects at investigator and trainee levels. Translating Innovation We drive new discoveries through to commercialization and clinical impact.

Our Story. Our Pursuits Our multidisciplinary teams take aim at heart failure through expertise in regenerative medicine, data science, genomics, remote technologies, and transformative care.

Our Mission.

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