Category: Health

Venom detoxification therapy

Venom detoxification therapy

kaouthiaproduces anti-nociceptive Vdnom anti-inflammatory effects through decreased production of Threapy cytokines, Weight loss fruits example, TNF-α, Plant-based recipes, and IL-2, via Supercharged energy supplements high affinity eVnom the α 7 subtype of nAChR Gazerani and Cairns, Based on this hypothesis, a single-anonymous, parallel groups, randomized controlled trial was designed and conducted to compare the clinical efficacy of these two treatment regimens. These medications bind to the metals, a process called chelation.

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Venom detoxification therapy -

Long-term exposure to metals can be toxic, causing harmful side effects that range from headaches to organ damage. Mercury , lead , arsenic and cadmium are some of the more common overexposed metals.

Many people get a buildup of heavy metals in their system because of the foods they eat. Some studies suggest you can prevent overexposure to these toxins by avoiding certain foods. Eating other foods known for taking heavy metals out of the system may also help.

Some foods can help you detoxify by getting rid of heavy metals from your body. These foods bind to the metals and remove them in the digestive process.

Eating foods high in vitamins and minerals can have protective effects for those exposed to heavy metals. Vitamin B, B-6, and C deficiencies are associated with poor tolerance of heavy metals and easier toxicity. Vitamin C has been reported to have chelating effects on iron. In one animal study , B-1 supplements were shown to decrease iron levels.

The U. An effective heavy metal detox includes more than incorporating healthy fruits and vegetables. To minimize the effects of heavy metal poisoning or prevent it altogether, you need to eliminate some foods from your diet.

This is especially true for processed foods and excess fats. These foods have minimal nutritional value and slow down the detox process. This is because fats tend to soak up the harmful substances you want to remove.

Heavy metal poisoning can trigger a number of harmful side effects. If left untreated, it can be life-threatening. Follow through with any recommended medical treatment. Talk to your doctor about how dietary changes can help protect you from heavy metal overexposure.

Before participating in the heavy metal detox diet, consult with your doctor or dietician to discuss your options. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

VIEW ALL HISTORY. Lead is a toxic metal and a very strong poison. Lead poisoning is serious and sometimes fatal. Learn the causes, treatments, and tips for prevention. Table 3. Comparison of wound necrosis volume with Cobra bite between two groups of patients.

Fig 2. Comparison of wound healing time with cobra bite between two groups of patients. Discussion Generally, cobra bites are characterized by high morbidity, and disability and often cause local tissue necrosis.

Conclusion Snakebite is a common clinical emergency, and local tissue necrosis caused by cobra bites is a difficult focus of clinical treatment.

Supporting information. S1 CONSORT Checklist. CONSORT checklist of information to include when reporting a randomized trial. s DOC. S1 Fig. Therapeutic schedule of local tissue necrosis caused by Chinese cobra Naja atra bites.

s TIF. Acknowledgments We would like to thank Dr. References 1. Seifert SA, Armitage JO, Sanchez EE. Snake Envenomation. The New England journal of medicine. Chen QF, Wang W, Li QB, Bai YL, Zou XY, Wu YB.

Effect of externally applied jidesheng anti-venom on skin and soft-tissue necrosis after Chinese cobra bite: a retrospective study.

View Article Google Scholar 3. Li ST, Wang JQ, Zhang XM, Ren Y, Wang N, Zhao K, et al. Proteomic characterization of two snake venoms: Naja naja atra and Agkistrodon halys.

Biochemical Journal. View Article Google Scholar 4. Wang W, Chen QF, Yin RX, Zhu JJ, Li QB, Chang HH, et al. Clinical features and treatment experience: A review of Chinese cobra snakebites. ENVIRON TOXICOL PHAR. Wong KY, Tan KY, Tan NH, Tan CH.

A Neurotoxic Snake Venom without Phospholipase A2: Proteomics and Cross-Neutralization of the Venom from Senegalese Cobra, Naja senegalensis Subgenus: Uraeus. View Article Google Scholar 6. Nayak AG, Kumar N, Shenoy S, Roche M. Anti-snake venom and methanolic extract of Andrographis paniculata: a multipronged strategy to neutralize Naja naja venom acetylcholinesterase and hyaluronidase.

Yang CC. Cobrotoxin: structure and function. Journal of natural toxins. Sun QY, Wang CE, Li YN, Bao J. Inhibition of platelet aggregation and blood coagulation by a P-III class metalloproteinase purified from Naja atra venom.

Toxicon: official journal of the International Society on Toxinology. View Article Google Scholar 9. Stefansson S, Kini RM, Evans HJ. The basic phospholipase A2 from Naja nigricollis venom inhibits the prothrombinase complex by a novel nonenzymatic mechanism.

View Article Google Scholar Kazandjian TD, Arrahman A, Still KBM, Somsen GW, Kool J. Anticoagulant Activity of Naja nigricollis Venom Is Mediated by Phospholipase A2 Toxins and Inhibited by Varespladib.

Rivel M, Solano D, Herrera M, Vargas M, Villalta M, Segura A, et al. Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis : An experimental study in mice. Wong OF, Lam TSK, Fung HT, Choy CH. Five-year experience with Chinese cobra Naja atra —related injuries in two acute hospitals in Hong Kong.

Liu CC, Chou YS, Chen CY, Liu KL, Chen CK. Pathogenesis of local necrosis induced by Naja atra venom: Assessment of the neutralization ability of Taiwanese freeze-dried neurotoxic antivenom in animal models.

PLOS NEGLECT TROP D. Su Z, Wang Y. Coarse-grained molecular dynamics simulations of cobra cytotoxin A3 interactions with a lipid bilayer: penetration of loops into membranes. The journal of physical chemistry.

B ; — Liu CC, You CH, Wang PJ, Yu JS, Huang GJ, Liu CH, et al. Analysis of the efficacy of Taiwanese freeze-dried neurotoxic antivenom against Naja kaouthia , Naja siamensis and Ophiophagus hannah through proteomics and animal model approaches.

Chong HP, Tan KY, Liu B, Sung W, Tan CH. Cytotoxicity of Venoms and Cytotoxins from Asiatic Cobras Naja kaouthia , Naja sumatrana , Naja atra and Neutralization by Antivenoms from Thailand, Vietnam, and Taiwan. Lin J, Sung W, Mu H, Hung D. Local Cytotoxic Effects in Cobra Envenoming: A Pilot Study.

Hsieh YH, Hsueh JH, Liu WC, Yang KC, Hsu KC, Lin CT, et al. Contributing Factors for Complications and Outcomes in Patients With Snakebite: Experience in a Medical Center in Southern Taiwan. ANN PLAS SURG. Mao YC, Liu PY, Chiang LC, Lai CS, Ho KL, Wang CH, et al.

Naja atra snakebite in Taiwan. Clinical toxicology Philadelphia, Pa. Study on the rationality of local blocking of chymotrypsin injection in the treatment of Chinese cobra bite envenoming: Guangxi Medical University.

Shah D, Mital K. The Role of Trypsin: Chymotrypsin in Tissue Repair. ADV THER. Li QB, Li CZ, Liang ZJ, Zhang JF, Wang W, RD L. Consensus of Chinese snake wound treatment experts in Snake records. Zeng LS, Zeng ZY, Liu YX, Zhang CC, Gao JH, Liu Q, et al. Clinical observation of acupuncture bloodletting at Ashi points on local swelling and pain after snakebite.

World Journal of Acupuncture-Moxibustion. Chen K. Chymotrypsin sleeve closure in the treatment of cases of snakebite.

Journal of Sino-Japanese Friendship Hospital. Ho CH, Chiang LC, Mao YC, Lan KC, Tsai SH, Shih YJ, et al. Analysis of the Necrosis-Inducing Components of the Venom of Naja atra and Assessment of the Neutralization Ability of Freeze-Dried Antivenom.

Liang Q, Huynh TM, Konstantakopoulos N, Isbister GK, Hodgson WC. An Examination of the Neutralization of In Vitro Toxicity of Chinese Cobra Naja atra Venom by Different Antivenoms. Leong PK, Sim SM, Fung SY, Sumana K, Sitprija V, Tan NH.

Cross neutralization of Afro-Asian cobra and Asian krait venoms by a Thai polyvalent snake antivenom Neuro Polyvalent Snake Antivenom. PLoS Negl Trop Dis. Wong KY, Tan KY, Tan NH, Gnanathasan CA, Tan CH. Elucidating the Venom Diversity in Sri Lankan Spectacled Cobra Naja naja through De Novo Venom Gland Transcriptomics, Venom Proteomics and Toxicity Neutralization.

Alomran N, Alsolaiss J, Albulescu LO, Crittenden E, Harrison RA, Ainsworth S, et al. Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms.

Suzuki-Matsubara M, Athauda SBP, Suzuki Y, Matsubara K, Moriyama A. Comparison of the primary structures, cytotoxicities, and affinities to phospholipids of five kinds of cytotoxins from the venom of Indian cobra, Naja naja. Aripov TF, Gasanov SE, Salakhutdinov BA, Rozenshtein IA, Kamaev FG.

Central Asian cobra venom cytotoxins-induced aggregation, permeability and fusion of liposomes. GEN PHYSIOL BIOPHYS. Feofanov AV, Sharonov GV, Dubinnyi MA, Astapova MV, Arseniev AS. Comparative study of structure and activity of cytotoxins from venom of the cobras Naja oxiana , Naja kaouthia , and Naja haje.

Hiu JJ, Yap MKK. The myth of cobra venom cytotoxin: More than just direct cytolytic actions. X ; Ebrahim K, Shirazi FH, Mirakabadi AZ, Vatanpour H. Cobra venom cytotoxins; apoptotic or necrotic agents. Wu MY, Ming W, Tang Y, Zhou SM, Kong TH, Dong WH.

The anticancer effect of cytotoxin 1 from Naja atra Cantor venom is mediated by a lysosomal cell death pathway involving lysosomal membrane permeabilization and cathepsin B release. The American journal of Chinese medicine. Liu YM, Ming W, Wang Y, Liu SH, Qiu YF, Xiang YX, et al. Cytotoxin 1 from Naja atra Cantor venom induced necroptosis of leukemia cells.

Lai CS, Liu PY, Lee CH, Ho CH, Chen WL, Lai KL, et al. The development of surgical risk score and evaluation of necrotizing soft tissue infection in Naja atra envenomed patients.

Yeh H, Gao SY, Lin CC. Wound Infections from Taiwan Cobra Naja atra Bites: Determining Bacteriology, Antibiotic Susceptibility, and the Use of Antibiotics-A Cobra BITE Study. Huang WH, Kao CC, Mao YC, Lai CS, Lai KL, Lai CH, et al.

Shewanella algae and Morganella morganii Coinfection in Cobra-Bite Wounds: A Genomic Analysis. Life Basel, Switzerland. Mao YC, Chuang HN, Shih HC, Hsieh HH, Jiang YH, Chiang LC, et al.

An investigation of conventional microbial culture for the Naja atra bite wound, and the comparison between culture-based 16S Sanger sequencing and 16S metagenomics of the snake oropharyngeal bacterial microbiota.

Alcohol detox is not a treatment for alcoholism. After detoxification, other treatments must be undertaken to deal with the underlying addiction that caused alcohol use. Clinicians use drug detoxification to reduce or relieve withdrawal symptoms while helping an addicted person adjust to living without drug use.

Drug detoxification does not aim to treat addiction but rather represents an early step within long-term treatment. Detoxification may be achieved drug-free or may use medications as an aspect of treatment. Often drug detoxification and treatment will occur in a community program that lasts several months and takes place in a residential setting rather than in a medical center.

Drug detoxification varies depending on the location of treatment, but most detox centers provide treatment to avoid the symptoms of physical withdrawal from alcohol and from other drugs. Most also incorporate counseling and therapy during detox to help with the consequences of withdrawal.

An animal's metabolism can produce harmful substances which it can then make less toxic through reduction , oxidation collectively known as redox reactions , conjugation and excretion of molecules from cells or tissues. Certain approaches in alternative medicine claim to remove alleged "toxins" from the body through herbal, electrical, electromagnetic or other treatments.

These toxins may not be linked to symptoms and treatments have no scientific evidence, [18] [19] making the validity of such techniques questionable.

There is little evidence for toxic accumulation in these cases, [19] as the liver and kidneys automatically detoxify and excrete many toxic materials including metabolic wastes.

Under this theory, if toxins are too rapidly released without being safely eliminated such as when metabolizing fat that stores toxins , they can damage the body and cause malaise.

Such alternative therapies include contrast showers , detoxification foot pads , oil pulling , Gerson therapy , snake-stones , body cleansing , Scientology 's and Narconon 's Purification Rundown , water fasting , and metabolic therapy.

Contents move to sidebar hide. Article Talk. Read Edit View history. Tools Tools. What links here Related changes Upload file Special pages Permanent link Page information Cite this page Get shortened URL Download QR code Wikidata item.

Download as PDF Printable version. In other projects. Wikimedia Commons. Removal of toxic substances from an organism. For other uses, see Detoxification disambiguation.

Doctors typically prescribe certain medications to remove tnerapy metals from your Plant-based recipes if Plant-based recipes experience tyerapy metal poisoning. Eating certain foods may Mind-body connection for satiety help. Heavy Venom detoxification therapy poisoning is the accumulation of various heavy metals in your body. Environmental and industrial factors expose you to high levels of heavy metals every day, including the foods you eat and air you breathe. Some of these metals — such as zinccopperand iron — are good for you in small amounts. If Supercharged energy supplements encounter detxoification like Supercharged energy supplements online, you need Energy-efficient manufacturing processes ask yourself four questions, thfrapy figure Supercharged energy supplements whether these claims really detoxificayion Venom detoxification therapy good to be true. Misinformation detoxifiation on Instagram and other social media includes a video of someone using cupping therapy, suggesting this removes or sucks out the COVID vaccine. Cupping has been used for thousands of years, mostly in traditional Chinese medicine. Practitioners believe this eases pain or promotes healing by drawing fluid towards the treated area and improve the flow of energy. However, there are few high-quality studies to support its effectiveness.

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