Creatine and muscle cramps -
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J Nutr Health Aging. Cornelissen VA, Defoor JG, Stevens A, et al. Effect of creatine supplementation as a potential adjuvant therapy to exercise training in cardiac patients: a randomized controlled trial. Clin Rehabil. Cornish SM, Candow DG, Jantz NT, et al. Conjugated linoleic acid combined with creatine monohydrate and whey protein supplementation during strength training.
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Resistance training with creatine monohydrate improves upper-body strength in patients with Parkinson disease: a randomized trial. Neurorehabil Neural Repair. Kingsley M, Cunningham D, Mason L, Kilduff LP, McEneny J. Role of creatine supplementation on exercise-induced cardiovascular function and oxidative stress.
Oxid Med Cell Longev. Kley RA, Tarnopolsky MA, Vorgerd M. Creatine for treating muscle disorders. Cochrane Database Syst Rev. Korzun WJ.
Oral creatine supplements lower plasma homocysteine concentrations in humans. Clin Lab Sci. McMorris T, Harris RC, Swain J, et al. Effect of creatine supplementation and sleep deprivation, with mild exercise, on cognitive and psychomotor performance, mood state, and plasma concentrations of catecholamines and cortisol.
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Witte KK, Clark AL, Cleland JG. Chronic heart failure and micronutrients. J Am Coll Cardiol. Share Facebook Twitter Linkedin Email Home Health Library. Creatine Phosphocreatine. Uses Athletic performance Most human studies have taken place in laboratories, not in people actually playing sports.
Heart disease Preliminary studies suggest that creatine supplements may help lower levels of triglycerides fats in the blood in men and women with high concentrations of triglycerides. Cancer Preliminary studies suggest that creatine may have anticancer properties. Chronic Obstructive Pulmonary Disease COPD One study found that people with COPD who took creatine increased muscle mass, muscle strength and endurance, and improved their health status compared with those who took placebo.
Muscular dystrophy People who have muscular dystrophy may have less creatine in their muscle cells, which may contribute to muscle weakness. Parkinson disease People with Parkinson disease PD have decreased muscular fitness, including decreased muscle mass, muscle strength, and increased fatigue.
Amyotrophic Lateral Sclerosis ALS or Lou Gehrig's disease Creatine appears to slow the progression of ALS and improves patients' quality of life.
Dietary Sources About half of the creatine in our bodies is made from amino acids in the liver, kidney, and pancreas.
Available Forms Supplements are commonly sold as powders. How to Take It Pediatric Creatine supplements are not recommended for children or teens. Adult Sample doses are below. You should ask your doctor to help determine the right dose for you.
Maintenance dose in exercise performance for adults ages 19 and older : Take 2 g daily. Precautions Because of the potential for side effects and interactions with medications, you should take dietary supplements only under the supervision of a knowledgeable health care provider. Side effects of creatine include: Weight gain Muscle cramps Muscle strains and pulls Stomach upset Diarrhea Dizziness High blood pressure Liver dysfunction Kidney damage Most studies have found no significant side effects at the doses used for up to 6 months.
People with kidney disease, high blood pressure, or liver disease should not take creatine. Possible Interactions If you are being treated with any of the following medications, you should not use creatine without talking to your doctor first.
Non steroidal anti-inflammatory drugs NSAIDs Taking creatine with these pain relievers may increase the risk of kidney damage.
Caffeine Caffeine may make it hard for your body to use creatine, and taking creatine and caffeine may increase the risk of dehydration. Perspectives on Exertional Rhabdomyolysis. Harris RC, Soderlund K, Hultman E. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation.
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Acute phase response in exercise: interaction of age and vitamin E on neutrophils and muscle enzyme release. Download references. Department of Health and Human Performance, Nova Southeastern University, Davie, Florida, USA. Faculty of Kinesiology and Health Studies, University of Regina, Regina, Canada.
Department of Physical Education, Faculty of Education, Brandon University, Brandon, MB, Canada. Sports Medicine Department, Mayo Clinic Health System, La Crosse, WI, USA. Department of Health, Nutrition, and Exercise Science, Messiah University, Mechanicsburg, PA, USA.
Department of Exercise and Sport Science, University of North Carolina, Chapel Hill, NC, USA. Department of Exercise Science and Sport Management, Kennesaw State University, Kennesaw, GA, USA.
School of Exercise and Sport Science, University of Mary Hardin-Baylor, Belton, TX, USA. The Center for Applied Health Sciences, Canfield, Ohio, USA. You can also search for this author in PubMed Google Scholar.
Conceptualization: DGC; Writing-original draft preparation: All authors. The authors declare that the content of this paper has not been published or submitted for publication elsewhere.
The author s read and approved the final manuscript. Correspondence to Jose Antonio. DGC has received research grants and performed industry sponsored research involving creatine supplementation, received creatine donation for scientific studies and travel support for presentations involving creatine supplementation at scientific conferences.
In addition, DGC serves on the Scientific Advisory Board for Alzchem a company which manufactures creatine and the editorial review board for the Journal of the International Society of Sports Nutrition and is a sports science advisor to the ISSN.
Furthermore, DGC has previously served as the Chief Scientific Officer for a company that sells creatine products. BG has received research grants, creatine donation for scientific studies, travel support for participation in scientific conferences includes the ISSN and honorarium for speaking at lectures from AlzChem a company which manufactures creatine.
In addition, BG serves on the Scientific Advisory Board for Alzchem a company that manufactures creatine. ARJ has consulted with and received external funding from companies that sell certain dietary ingredients and also writes for online and other media outlets on topics related to exercise and nutrition.
RBK is co-founder and member of the board of directors for the ISSN. In addition, RBK has conducted industry sponsored research on creatine, received financial support for presenting on creatine at industry sponsored scientific conferences includes the ISSN , and served as an expert witness on cases related to creatine.
Additionally, he serves as Chair of the Scientific Advisory Board for Alzchem that manufactures creatine monohydrate. ESR serves on the Scientific Advisory Board for Alzchem a company which manufactures creatine.
AESR has received research funding from industry sponsors related to sports nutrition products and ingredients. In addition, AESR serves on the Scientific Advisory Board for Alzchem a company that manufactures creatine.
TAV has received funding to study creatine and is an advisor for supplement companies who sell creatine. In addition, TAV is the current president of the ISSN. DSW serves as a scientific advisor to the ISSN and on the editorial review board for the Journal of the International Society of Sports Nutrition.
In addition, DSW is Past President of the ISSN and has received financial compensation from the ISSN to speak about creatine supplementation.
TNZ has conducted industry sponsored research involving creatine supplementation and has received research funding from industry sponsors related to sports nutrition products and ingredients. In addition, TNZ serves on the editorial review board for the Journal of the International Society of Sports Nutrition and is Past President of the ISSN.
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Download PDF. Download ePub. Review Open access Published: 08 February Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? Jose Antonio ORCID: orcid. Candow 2 , Scott C. Forbes 3 , Bruno Gualano 4 , Andrew R.
Jagim 5 , Richard B. Kreider 6 , Eric S. Rawson 7 , Abbie E. Smith-Ryan 8 , Trisha A. VanDusseldorp 9 , Darryn S. Ziegenfuss 11 Show authors Journal of the International Society of Sports Nutrition volume 18 , Article number: 13 Cite this article k Accesses 50 Citations Altmetric Metrics details.
Abstract Supplementing with creatine is very popular amongst athletes and exercising individuals for improving muscle mass, performance and recovery. Introduction Creatine methylguanidine-acetic acid is endogenously formed from reactions involving the amino acids arginine, glycine and methionine in the kidneys and liver [ 1 ].
Creatine supplementation strategies. Full size image. Conclusions Based on our evidence-based scientific evaluation of the literature, we conclude that: 1. Creatine supplementation does not always lead to water retention. Creatine is not an anabolic steroid.
Creatine supplementation does not cause dehydration or muscle cramping. Creatine supplementation does not increase fat mass. Creatine supplementation can be beneficial for a variety of athletic and sporting activities.
Creatine supplementation provides a variety of benefits for females across their lifespan. Other forms of creatine are not superior to creatine monohydrate.
Availability of data and materials Not applicable. Abbreviations ACSM: American College of Sports Medicine ATP: Adenosine triphosphate C: Celsius CK: Creatine kinase CSA: Controlled substances act DEA: Drug enforcement association DHT: Dihydrotestosterone DSHEA: Dietary Supplement Health and Education Act ECW: Extracellular water FDA: Food and Drug Administration G: Grams GMP: Good Manufacturing Practices ICW: Intracellular water ISSN: International Society of Sports Nutrition Kg: Kilogram Km: Kilometer L: Liter MPS: Muscle protein synthesis NCAA: National Collegiate Athletic Association Nmol: Nanomole Oz: Ounce PCr: Phosphocreatine pH: Potential hydrogen s: Seconds pKa: Acid dissociation constant P i : Inorganic phosphate TBW: Total body water Yrs: Years of age.
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About a month ago, a year-old insurance executive Creatine and muscle cramps to see Creatine and muscle cramps Creatins complaints of Insulin secretion disorders and Creahine cramps. His Crdatine was caused muzcle the typical cluster headache located behind one eye, Crreatine by one-sided tearing and nasal mkscle, and often triggered by occasional wine or chocolate. The muscle cramps mainly affected the legs and seemed to worsen after exercise. When I got the results of his lab work, I was surprised to see an elevated muscle enzyme level creatine phosphokinase or CPK. When I called my patient with the result, he admitted that he had been taking creatine supplements a few times a week to improve his workout and help him increase his weightlifting.Video
Does Creatine cause Water retention \u0026 Muscle Cramps ?? Many wnd by the supplement's Creattine to help build muscle musc,e and improve performance; others worry muscl its potential Creatine and muscle cramps effects, particularly muscle cramping. Is creatine Functional movement training linked to cramped muscles? The research does not support this claim. In fact, creatine may actually help to prevent muscle tightness or cramps. If you are considering taking creatine, it is important to consult with a healthcare provider first. This is especially true if you have any underlying health conditions or take medications that could interact with creatine.
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