Accelerate fat oxidation -
CAS Google Scholar. Achten J, Gleeson M, Jeukendrup AE. Determination of the exercise intensity that elicits maximal fat oxidation.
Med Sci Sports Exerc. Valizadeh A, Khosravi A, Azmoon H. Fat oxidation rate during and after three exercise intensities in non-athlete young men. World Appl Sci J. Randell RK, Rollo I, Roberts TJ, Dalrymple KJ, Jekendrup AE, Carter JM.
Maximal fat oxidation rates in an athletic population. Ogasawara J, Izawa T, Sakurai T, Sakurai T, Shirato K, Ishibashi Y, Ishida H, Ohno H, Kizaki T. The molecular mechanism underlying continuous exercise training-induced adaptive changes of lipolysis in white adipose cells.
J Obesity. Watt M, Spriet LL. Triacylglycerol lipases and metabolic control: implications for health and disease. Am J of Physol. Endocrinol Metab. Zechner R, Kienesberger PC, Haemmerle G, Zimmermann R, Lass A.
Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores. J Lipid Res. van Loon L, Greenhaff PL, Constantin-Teodosiu D, Wagenmakers AJ. The effects of increasing exercise intensity on muscle fuel utilisation in humans.
J Physiol. Article CAS PubMed PubMed Central Google Scholar. Tank A, Wong D. Peripheral and central effects of circulating catecholamines. Compr Physol.
van Hall G. THe physiological regulation of skeletal muscle fatty acid supply and oxidation during moderate-intensity exercise. Sports Med. Zouhal H, Jacob C, Delamarche P, Grata-Delamarche A.
Catecholamines and the effects of exercise, training and gender. Horowitz J, Klein S. Lipid metabolism during endurance exercise.
Am J Clin Nutr. Frayn K. Fat as fuel: emerging understanding of the adipose tissue-skeletal muscle axis. Acta Physiol.
Article CAS Google Scholar. Spriet LL. New insights into the interaction of carbohydrate and fat metabolism during exercise. Kiens B. Skeletal muscle lipid metabolism in exercise and insulin resistance. Physol Rev. Shaw C, Clark J, Wagenmakers A. The effect of exercise and nutrition on intramuscular fat metabolism and insulin sensitivity.
Annu Rev Nutr. Moro C, Bajpeyi S, Smith SR. Determinants of intramyocellular triglyceride turnover: implications for insulin sensitivity. Am J Physiol Endocrinol Metab. Wong H, Schotz MC. The lipase gene family. van Loon L, Greenhaff P, Constantin-Teodosiu D, Saris W, Wagenmakers A.
Use of intramuscular triacylgylcerol as a substrate source during exercise in humans. J Appl Physiol. Watt M, Heigenhauser G, Spriet LL. Intramuscular triacylgylerol utilization in human skeletal muscle during exericse: is there a controversy? Jeppesen J, Keins B. Regulation and limitations to fatty acid oxidation during exercise.
J Phys. Yoshida Y, Jain SS, McFarlan JT, Snook LA, Chabowski A, Bonen A. Exercise- and training-induced upregulation of skeletal muscle fatty acid oxidation are not solely dependent on mitochondrial machinery and biogenesis. Schenk S, Horowitz JF.
Klien S, Coyle E, Wolfe R. Fat metabolism during low-intensity exercise in endurance-trained and untrained men. Am J Phys. Lundsgaard A, Kiens B. Gender differences in skeletal muscle substrate metabolism-molecular mechanisms and insulin sensitivity.
Front Endocrinol. Oosthuyse T, Bosch A. The effect of the menstual cycle on exercise metabolism. Kiens B, Roepstorff C, Glatz J, Bonen A, Schjerling P, Knudsen J, Nielsen J. Lipid-binding proteins and lipoprotein lipase activity in human skeletal muscle: influence of physical activity and gender.
DeLany J, Windhauser M, Champagne C, Bray G. Differential oxidation of individual dietary fatty acids in humans. CAS PubMed Google Scholar. Misell L, Lagomarcino N, Shuster V, Kern M. Chronic medium-chain triacylglycerol consumption and endurance performance in trained runners.
J Sports Med Phys Fit. Jeukendrup A, Aldred S. Fat supplementation, health, and endurance performance. Volek J, Freidenreich D, Saenz C, Kunces L, Creighton B, Bartley, Davitt P, Munoz C, Anderson J, Maresh C, Lee E, Schuenke M, Aerni G, Kramer W, Phinney S. Metabolic characteristics of keto-adapted ultra-endurance runners.
Yeo W, Carey A, Burke L, Spriet LL, Hawley J. Fat adaptation in well-trained athletes: effects on cell metabolism. Appl Physiol Nutr Metab. Jeukendrup AE. Fat metabolism during exercise: a review.
Part III: effects of nutritional interventions. Int J Sports Med. Calvani M, Reda E, Arrigoni-Martelli E. Regluation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions. Basic Res Cardiol. Stephens F, Constantin-Teodosiu D, Greenhaff P. New insights concerning the role of carnitine in the regulaiton of fuel metabolism in skeletal muscle.
Article PubMed PubMed Central Google Scholar. Lima-Silva A, Bertuzzi R, Pires F, Gagliardi J, Barros R, Hammond J, Kiss M. Relationship between training status and maximal fat oxidation. J Sports Sci Med. PubMed PubMed Central Google Scholar. Scharhag-Rosenberger FM, Meyer T, Walitzek S, Kindermann W.
Effects of one year aerobic endurance training on resting metabolic rate and exercise fat oxidation in previously untrained men and women. Metabolic endurance training adaptations. Bircher S, Knechtle B. Relationship between fat oxidation and lactate threshold in athletes and obese women and men.
Nordby P, Saltin B, Helge JW. Whole-body fat oxidation determined by graded exercise and indirect calorimetry: a role for muscle oxidative capacity? Scand J Med Sci Sports. Lanzi S, Codecasa F, Cornacchia M, Maestrini S, Slvadori A, Brunani A, Malatesta D. Fat oxidation, hormonal and plasma metabolite kinetics during a submaximal incremental test in lean and obese adults.
PLoS One. Stisen A, Stougaard O, Langfort J, Helge J, Sahlin K, Madsen K. Maximal fat oxidation rates in endurance trained and untrained women. Eur J Appl Physiol. Watt M, Heigenhauser G, Dyck D, Spriet LL.
Intramuscular triacylglycerol, glycogen, and acetyl group metabolism during 4 h of moderate exercise in man. Mora-Rodriguez R, Hodgkinson BJ, Byerley LO, Coyle EF. Effects of -adrenergic receptor stimulation and blockade on substrate metabolism during submaximal exercise.
Am J Physol. Martin W. Effects of acute and chronic exercise on fat metabolism. Exerc Sport Sci Revs. Romijn J, Coyle E, Sidossis L, Gastaldelli A, Horowitz J, Endert E, Wolfe R. Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration.
Am J phys. Bergomaster K, Howarth KR, Phillips SM, Rakobowchuk M, MacDonald MJ, McGee SL, Gibala MJ. Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humans.
Article Google Scholar. Astorino T. Is the ventilatory threshold coincident with maximal fat oxidation during submaximal exercise in women? J Sports Med Phys Fitness. Turcotte L, Richeter E, Kiens B. Increased plasma FFA uptake and oxidation during prolonged exericse in trained vs.
untrained humans. Effect of endurance training on fatty acid metabolism during whole body exercise. Isacco L, Duché P, Buisseau N. Influence of hormonal status on substrate utilization at rest and during exercise in the female population. Maher A, Akhtar M, Vockley J, Tarnopolosky M.
Women have higher protein content of beta oxidation enzymes in skeletal muscle than men. Tarnopolosky M. Sex differences in exercise metabolism and the role of beta estradiol. Varmlamov O, Bethea CL, Roberts CT. Sex-specific differences in lipid and glucose metabolism. Dasilva SG, Guidetti L, Buzzachera CF, Elsangedy HM, Krinski K, De Campos W, Goss FL, Baldari C.
Gender-based differences in substrate use during exercise at a self-selected pace. J Strength Cond Res. Carter S, Rennie C, Tarnopolosky M.
Substrate utilization during endurance exercise in men and women after endurance training. Am J Endocrinoly Metab. Lebrun C. Effect of the different phases of the menstrual cycle and oral contraceptives on athletic performance. Maher A, Akhtar M, Tarnopolsky M.
Men supplemented with 17b-estradiol increased b-oxidation capacity in skeletal muscle. Physiol Genomics. Fletcher G, Eves FF, Glover EI, Robinson SL, Vernooij CA, Thompson JL, Wallis GA. Dietary intake is independently associated with the maximal capacity for fat oxidation during exercise.
Phinney S. Ketogenic diets and physical performance. Nutr Metab. Burke L. Re-examining high-fat diets for sports perfomance: did we call the 'nail in the coffin' too soon? Hawley J, Leckey J. Carbohydrate dependence during prolonged, intense endurance exercise.
Ochiai M, Matsuo T. Effects of short-term dietary change from high-carbohydrate diet to high-fat diet on storage, utilization, and fatty acid composition of rat muscle triglyceride during swimming exercise.
J Clin Biochem Nutr. Miles-Chan J, Dulloo AG, Schutz Y. Fasting substrate oxidation at rest assessed by indirect calorimetry: is prior dietary macronutrient level and composition a confounder? Int J Obes. Stellingwerff T, Spriet LL, Watt M, Kimber N, Hargreaves M, Hawley J, Burkey L.
Decreased PDH activiation and glycogenolysis during exercise following fat adaptation with carbohydrate resortation.
Am J Endocrinol Metab. Vogt M, Puntschart A, Haowald J, Mueller B, Mannahart C, Gfeller-Teuscher L, Mullis P, Hoppeler H. Effects of dietary fat on muscle substrates, metabolism, and performance in athletes.
Pilegaard H, Keller C, Seensberg A, Helge J, Pedersen B, Saltin B, Neufer D. Influence of pre-exercise muscle glycogen content on exercise-induced transcriptional regulation of metabolic genes. Burke L, Hawley J, Angus D, Cox G, Clark S, Cummings N, Desbrow B, Hargreaves M. Studies suggest that replacing fat in your diet with 1.
Try to start with 1 teaspoon tsp and gradually increase to avoid digestive side effects. Coffee is one of the most popular beverages worldwide. Coffee a great source of caffeine , which may help you burn fat. To get the fat-burning benefits of caffeine without the potential side effects , such as anxiousness or insomnia, aim for no more than mg per day.
This is the amount found in about 4—5 cups of coffee, depending on its strength. Although egg yolks have traditionally been avoided due to their high cholesterol content, whole eggs may help with weight loss. For one, they are very nutrient-dense and contain a lot of protein, which can help ward off hunger and overeating.
One of the reasons eggs are so filling may also be due to the boost in calorie burning that occurs during protein digestion. Eating up to three eggs a week can help you burn fat while keeping you full and satisfied. More than this amount has been associated with a higher chance of heart disease. In addition to providing a moderate amount of caffeine, green tea is an excellent source of epigallocatechin gallate EGCG , an antioxidant that promotes fat burning and the loss of belly fat.
Though research suggests that drinking green tea may help improve your metabolism and lower your body fat, more research is necessary to support these claims.
That said, drinking about cups of green tea daily may be optimal for providing the variety of health benefits.
Moreover, whey appears to boost fat burning and promote weight loss. For this reason, a whey protein shake is a quick meal or snack option that promotes fat loss and may help improve your body composition. Apple cider vinegar is an ancient folk remedy with evidence-based health benefits.
However, more human studies are needed to verify this. Start with 1 tsp per day diluted in water and gradually work up to 1 tbsp per day to minimize potential digestive discomfort. Chili peppers contain powerful antioxidants. One of these is called capsaicin , and cosuming it may help you achieve and maintain a healthy weight by promoting fullness and preventing overeating.
Consider eating chili peppers or using powdered cayenne pepper to spice up your meals several times a week. Oolong tea is contains polyphenols , which are compounds associated with helping reduce things like blood sugar and and body weight.
Like other teas, it also contains caffeine, which helps promote weight and body fat loss. Drinking a few cups of green tea, oolong tea, or a combination of the two on a regular basis may promote fat loss and provide other beneficial health effects.
That said, most research on oolong tea and weight loss is based on animals, so more human studies are needed. Full-fat Greek yogurt is extremely nutritious.
Research also suggests that eating high protein dairy products can boost weight and fat loss. Eating 2 servings of dairy such as Greek yogurt daily may provide a number of health benefits.
But make sure to choose plain, full-fat Greek yogurt. Olive oil is one of the healthiest fats on earth. Most of olive oil is composed of oleic acid, which has been shown to have a positive effect on fat and body mass.
To incorporate olive oil into your daily diet, drizzle a couple of tablespoons on your salad or add it to cooked food. Drinks that may help you lose fat include tea, coffee, certain protein shakes, and vegetable juices. The effect of endurance training on the contribution of different fat sources to total fat oxidation after endurance training is under debate.
Part of this controversy could be explained by the methodological difficulties in using [ 13 C]- and [ 14 C]-fatty acid tracers to estimate the oxidation of plasma fatty acids, especially in the resting state However, Sidossis et al.
We showed that this acetate recovery is reproducible 25 but has a high interindividual variation and is influenced by infusion period, metabolic rate, respiratory quotient, and body composition 21 and therefore needs to be determined in every individual under similar conditions and at similar time points as the measurement of plasma-derived fatty acid oxidation.
In the present study, we therefore measured the acetate recovery factor at all time points in each individual both before and after the training program at least 7 days separated from the last training session to exclude the influence of the last exercise bout on the measurements and were therefore able to correct plasma-derived fatty acid oxidation rate for loss of label in the TCA cycle.
With the available stable isotope tracer methodology, we cannot distinguish between IMTG- or VLDL-derived fatty acid oxidation. Using electron microscopy, it has previously been shown that endurance-trained athletes have increased IMTG concentrations 36 , and because endurance athletes have an increased fat oxidation capacity, it seems logical that this increased IMTG storage after endurance training is an adaptation mechanism to allow IMTG oxidation during exercise.
The localization of the IMTG near the mitochondria would make these triglyceride pools an efficient source of substrate, especially during exercise.
However, biochemical analysis of IMTGs is problematic, and therefore the use of IMTG remains controversial. On the other hand, the contribution of VLDL-derived fatty acids to fat oxidation during exercise is also still under debate 18 , The increased expression of LPL mRNA after training, as observed in our study, which is in accordance with previous studies showing increased LPL activity after endurance training in rodents 38 , 39 , and the reduced plasma triglyceride levels after the training program suggest that VLDL-derived fatty acids contribute significantly to total fat oxidation.
Alternatively, an increase in LPL after training might serve to provide fatty acids for the replenishment of IMTGs that have been oxidized during exercise Certainly, further studies are needed to clarify the contribution of IMTG- and VLDL-derived fatty acid oxidation to total fat oxidation.
Another important aspect of the present study is that we have examined the effect of a low-intensity training program for only 2 h per week. Because endurance training has been shown to increase the capacity to oxidize fatty acids, it has been proposed to be beneficial in overcoming the disturbances in fat oxidation often observed in obesity and diabetes 9.
To investigate the mechanisms behind the changes in substrate oxidation after the endurance-training program, we measured mRNA levels of several genes involved in glucose and fatty acid metabolism.
A muscle biopsy was taken 6—7 days before the training program and 6—7 days after the last training session to exclude the influence of acute exercise on mRNA expression. The expression of two genes involved in regulatory steps of glucose metabolism, i.
As mentioned above, mRNA expression of LPL, which hydrolyzes plasma triglycerides and directs the released FFAs into the tissue 22 , tended to increase after training, suggesting that the capacity of skeletal muscle to hydrolyze VLDL triglycerides may be improved by the training program.
Inside the muscle cell, ACC2 activity has recently been suggested to control the rate of fatty acid oxidation and triglyceride storage ACC2 catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA, an intermediate that inhibits the activity of CPT1.
CPT1 catalyzes the rate-limiting step in the transfer of fatty acyl-CoA into mitochondria, where they undergo oxidation. Although we were not able to measure ACC2 enzyme activity, it is tempting to speculate that a decrease in ACC2 activity after training was responsible for the observed training-induced increase in fat oxidation.
Because high levels of malonyl-CoA have been associated with insulin resistance 42 , the reduction of ACC2 with endurance training could possibly be beneficial in the treatment of type 2 diabetes.
Finally, we determined the expression of the human UCP3, which has recently also been implicated in the transport of fatty acids across the inner mitochondrial membrane In a cross-sectional study, we have previously found that UCP3 mRNA was lower in trained than in untrained subjects In the present study, we did not find a significant effect of the training program on UCP3 mRNA expression, suggesting that the training program was not severe enough to result in changes in UCP3 mRNA.
Remarkably, we recently found that, in the same study, UCP3 protein content was significantly decreased after training in all subjects The reason for the discrepancy between the effect of training on UCP3 mRNA expression and protein cannot be deduced from the present study but might involve posttranslational regulation, although the number of subjects is too limited to make such a conclusion.
The mechanism behind this adaptation seems to involve a chronic upregulation of LPL mRNA expression and a chronic downregulation of ACC2, potentially leading to lower malonyl-CoA concentration and less inhibition of CPT1.
In contrast to moderate- to high-intensity endurance training, the mild training protocol did not increase hexokinase II and GLUT4 expression, indicating that specifically fat oxidation was improved. This study was supported by a grant from the Netherlands Organization for Scientific Research NWO to P.
and a grant from the Netherlands Heart Foundation to D. The laboratories are members of the Concerted Action FATLINK FAIR-CT , supported by the European Commission. The authors thank Paulette Vallier for help in mRNA analysis and Dr.
Diraison for making and validating the ACC2 competitor. Address correspondence and reprint requests to Dr. Schrauwen, Department of Human Biology, Maastricht University, P.
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Volume 51, Issue 7. Previous Article Next Article. RESEARCH DESIGN AND METHODS. Article Information. Article Navigation. Pathophysiology July 01 The Effect of a 3-Month Low-Intensity Endurance Training Program on Fat Oxidation and Acetyl-CoA Carboxylase-2 Expression Patrick Schrauwen ; Patrick Schrauwen.
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Br J Nutr. Zurlo F, Larson K, Bogardus C, Ravussin E: Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest. Blaak EE, van Aggel-Leijssen DP, Wagenmakers AJ, Saris WH, van Baak MA: Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise.
Colberg SR, Simoneau J-A, Thaete FL, Kelley DE: Skeletal muscle utilization of free fatty acids in women with visceral obesity. He J, Watkins S, Kelley DE: Skeletal muscle lipid content and oxidative enzyme activity in relation to muscle fiber type in type 2 diabetes and obesity.
Pan DA, Lillioja S, Kriketos AD, Milner MR, Baur LA, Bogardus C, Jenkins AB, Storlien LH: Skeletal muscle triglyceride levels are inversely related to insulin action.
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