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Glutathione for skin lightening -

There are many articles that suggest that Glutathione can be used for skin lightening and has been rumored to be used by celebrities ranging from Beyonce to Michael Jackson, but is it safe? Glutathione is a substance that occurs naturally in the body and it is produced in the liver.

It is also found in a range of the foods we eat, such as various fruits and vegetables. However, as a substance or treatment option, Glutathione is not approved by the FDA. So despite being available online and in places like Amazon, the sale of Glutathione in the form of a skin whitening capsule for instance is not regulated in any way.

The FDA approval is important, as we currently do not understand what the long-term health risks a patient may be putting themselves at risk of are. Various studies have been performed recently too, such as this one by the US National Library of Medicine , but there is no conclusive evidence of it working for skin lightening yet.

There are however a number of FDA-approved treatments for skin lightening on the market that are much more suitable and safer than Glutathione.

These methods even work in darker skin patients. Skin lightening can also be achieved via chemical peels, which safely and effectively lightens skin even in patients with the darkest pigmentation. One option that she often uses with chemical peels is Cosmelan, a skin bleaching peel that works on all skin types.

In many cases Dr. These creams and peels can be used on various areas of the body, not just on the face, but also the arms, legs, chest and torso. It is available in oral, parenteral and topical forms. Although the use of intravenous glutathione injections is popular, there is no evidence to prove its efficacy.

In fact, the adverse effects caused by intravenous glutathione have led the Food and Drug Administration of Philippines to issue a public warning condemning its use for off-label indications such as skin lightening.

Currently, there are three randomized controlled trials that support the skin-lightening effect and good safety profile of topical and oral glutathione. However, key questions such as the duration of treatment, longevity of skin-lightening effect and maintenance protocols remain unanswered.

More randomized, double-blind, placebo-controlled trials with larger sample size, long-term follow-up and well-defined efficacy outcomes are warranted to establish the relevance of this molecule in disorders of hyperpigmentation and skin lightening.

Abstract Glutathione is a low molecular weight thiol-tripeptide that plays a prominent role in maintaining intracellular redox balance. Publication types Review.

The wonder compound removes Glutathiome radicals, lihgtening and heavy metals. Glucagon receptor signaling improves energy production, Glutathione for skin lightening immunity, delays early signs Low glycemic for energy ageing skin, among many others. Glutathione fights oxidative stress, which is an imbalance between free radicals and antioxidants in the body. When free radicals accumulate they cause damage to cells. And we see the deficiency manifest as wrinkles, inflammation, hyperpigmentation and melasma. Introducing glutathione can help combat some of those unsightly, confidence-lowering effects.