Companies like UNITY Biotechnology NASDAQ: UBX and Elysium are at the forefront of this innovative field. UNITY Biotechnology NASDAQ:UBX is a vanguard in the fight against age-related diseases, is diving deep into the potential of foselutoclax , a phosphate pro-drug, and its active parent molecule, UBX, a BCL-xL inhibitor.

This ambitious research project seeks to treat, potentially slow, halt, or even reverse age-related decline.

Driven by the immense economic, personal, and societal burden of conditions like vision loss and cognitive decline in aging populations, UNITY Biotechnology NASDAQ:UBX is targeting the root causes of these diseases.

In the burgeoning anti-aging market, Natural Grocers by Vitamin Cottage Inc NYSE: NGVC , a leading organic and specialty grocer, is blooming into a major player. Natural Grocers by Vitamin Cottage Inc NYSE:NGVC extends its reach with leases signed for 5 new stores, bolstering its presence in fiscal years and beyond.

During its Q4 earnings call , Natural Grocers by Vitamin Cottage NYSE:NGVC painted a vibrant picture of robust customer activity and increasing sales. Daily average comparable store sales blossomed by 6. Furthermore, Natural Grocers by Vitamin Cottage NYSE:NGVC highlighted particularly stellar performances from several departments: dairy, body care, meat, and, most strikingly, dietary supplements.

The continued surge in supplement sales was incredibly encouraging, reflecting the company's distinct positioning in this crucial and margin-accretive category. According to the CRN survey , the US supplement market paints a fascinating picture of resilience and personalized choices.

This positive sentiment is a powerful catalyst for continued growth and innovation, paving the way for a dynamic future in the US supplement market.

Professor David Sinclair, a renowned researcher at Harvard Medical School, stands at the forefront of a scientific revolution redefining our understanding of aging. Sinclair's work centers around sirtuins, a family of protein-modifying enzymes activated by calorie restriction and other stress factors.

He theorizes that sirtuins act as cellular guardians, protecting against DNA damage and promoting healthy gene expression.

This, he proposes, translates to a slower aging process and decreased risk of age-related diseases like Alzheimer's and cardiovascular disease.

His research portfolio boasts an impressive array of findings. They've also shown that manipulating the activity of other longevity-related genes can improve healthspan and mitigate age-related decline in tissues like the brain and muscles. Professor David Sinclair's pioneering work stands as a testament to the boundless potential of scientific inquiry in resolving the mysteries of aging.

While challenges remain, his findings ignite hope in pursuing a longer, healthier life for all. In order to curate our list of 10 Supplements for Longevity and Antiaging: Expert Recommendations, we sifted through numerous industry reports, including CRN Survey , NIH , and Naresuan University Journal.

We also went through various web links, i. In addition, we also incorporated recommendations from a YouTube video by Wellness Messiah with Rimon. In addition, we also incorporated recommendations from a YouTube video by Wellness Messiah with Rimon, in which David Sinclair talks about Supplements for Longevity and Antiaging.

We counted how often each supplement was mentioned in our research, and the ones mentioned most frequently made our list of 10 Supplements for Longevity and Antiaging: Expert Recommendations.

By the way, Insider Monkey is an investing website that tracks the movements of corporate insiders and hedge funds. Using a similar consensus approach, we identify the best stock picks of over hedge funds investing in US stocks. Whether you are a beginner investor or a professional looking for the best stocks to buy, you can benefit from the wisdom of hedge funds and corporate insiders.

Niacin, a vital B vitamin, sits at the heart of energy production, keeping your nervous system, digestion, and skin function humming. Beyond its daily duties, however, niacin holds potential for longevity and anti-aging enthusiasts.

This translates to a healthy 5. While further research is necessary, current studies suggest that niacin's ability to regulate DNA repair and energy metabolism may promote healthy aging.

The recommended daily intake for adults is 16 mg for men and 14 mg for women non-pregnant. Always consult your healthcare provider before adding any new supplements to your regimen, especially if you have underlying health conditions.

The big question? NMN or NR as the booster? Many products choose one from NMN or NR for easier comparison, while others combine both or even include additional "youthful ingredients. Only be swayed by extras if their levels are significant. Alpha-lipoic acid ALA , a naturally occurring antioxidant powerhouse, is making waves in the anti-aging and longevity world, and for good reason.

Its versatility shines through its ability to act inside and outside cells, scavenging harmful free radicals that can damage our DNA and accelerate aging. This isn't just theoretical speculation; scientific studies suggest ALA's potential to improve mitochondrial function, the energy engines of our cells, thereby promoting cellular health and potentially delaying age-related decline.

This surge reflects growing awareness of its potential benefits and ongoing research exploring its role in neurodegenerative diseases, diabetes, and cardiovascular health. This surging demand reflects a growing awareness of ALC's potential to combat age-related decline.

A recent study by scientists underscores ALC's potential, demonstrating its safe and well-tolerated profile in pre-frail elderly subjects. How to Create a Home Gym. Personal Tech. Store Medical Records on Your Phone?

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A Pill to Slow Aging? Medical Advancements in Brain Health. Medical Advancements in Chronic Pain Treatment. For decades now, scientists have been searching for such a medical Holy Grail: safe medicines that treat aging as a whole by slowing cellular decay or by making your body more resilient to the factors that trigger physical and mental decline.

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Join Now. Despite the research costs and scientific challenges, the path toward such a pill is attracting more interest than ever. The federal government is involved , as well as many prominent academic institutions.

Finding a way to keep these adults healthy in their latter decades not only enhances their quality of life, but experts say it could be a boon for the economy and a break for the health care system, which shells out trillions of dollars each year to treat chronic diseases that become more common with age.

A dearth of data. While various medicines are showing promise in animals, it will take considerable time and money to test their long-term impact on humans. However, experts in the field are hopeful this will change. Promising treatments that never panned out, like resveratrol or biotech-backed experimental drugs, have also muddied the course.

Privacy Policy. The diabetes medication taken by millions has been under the anti-aging microscope for years, and experts say it remains a front-runner in the race toward a broad-purpose anti-disease drug. Studies show metformin has protective benefits against cardiovascular disease and may be able to reduce the risk of other age-related illnesses like cancer, dementia and stroke.

More recent research published in July in Aging Cell found the decades-old medication may also protect against loss of muscle in older adults. Barzilai is in the process of launching a large, six-year clinical trial, called TAME , to test whether older adults taking metformin can escape, or at least delay, the development of age-related diseases.

He hopes the 3,person study will also show that the aging process can be a target for drug development, which could help usher in other drug approvals. Researchers are instead working off a patchwork of grants and donations.

But those in the know predict the trial will be ready to go in a few years. Target Optical. Rapamycin, discovered in the s, is currently used to help prevent organ rejection after a kidney transplant and to treat certain types of cancer. In mice, Austad says, it does much more.

It has repeatedly been shown to help prevent cancer in rodents and slow down the progression of dementia. Researchers say it helps mice maintain their muscle , delays heart disease and improves vaccine response.

A pivotal study found that the drug can extend the life of older mice by 14 percent for females and 9 percent for males by postponing disease; other studies have produced similar results. The focus now is on humans and whether rapamycin will afford them the same disease-delaying benefits.

A small number of early-phase human trials are underway. Dog trials , too — and those are the ones to pay attention to while we wait for more human data. Get instant access to members-only products and hundreds of discounts, a free second membership, and a subscription to AARP the Magazine.

This newer class of drugs takes aim at senescent cells, also called zombie cells, which are damaged cells that refuse to die. As we age, the body becomes less effective at removing them, so they start to accumulate and release chemicals that can cause inflammation , damaging neighboring cells and driving disease, Barzilai says.

Some senolytics have been approved by the FDA to treat conditions like cancer; others are naturally occurring and are sold as supplements. Private companies are also pouring money into senolytics research — so stay tuned. In fact, that cautionary advice holds true for all products that claim to cure aging.

The most powerful prescriptions for now, medical researchers agree, are the everyday habits that help keep the body and brain in top shape — diet, exercise, sleep and meaningful relationships.

One day, a pill may be more effective than these. It may be years away or never truly achieved. Rachel Nania is an award-winning health editor and writer at AARP. org, who covers a range of topics including diseases and treatments. Discover AARP Members Only Access.

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