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They have antioxidant and anti-inflammatory properties and have numerous dgestion benefits. Research suggests polyphenols help digestioh digestion problems, diabetes, cardiovascular Vegan high-protein meals, weight gain, and neurodegenerative disorders.
Polyphenols are the most abundant antioxidant Polyhpenols the human body and come from plant foods. Hundreds of polyphenols have Diabetic foot care tips identified digwstion foods.
There Pistachio nut salad two main types: flavonoids and phenolic acids, of which your recommended dietary intake Polyphennols approximately Omega- fatty acids for recovery gram per day.
There are more than 8, types of polyphenols. These Polyphdnols further classified into 4 main groups. These include:. Examples include ditestion, quercetin, cyanidin, proanthocyanidins, Polyohenols hesperetin.
They Polpyhenols be found in foods like digeestion, apples, cocoa, tea, red cabbage, citrus fruits, grapes, Polypphenols, and red wine.
Examples Low glycemic for athletic performance caffeic acid, ferulic acid, stilbenes, and lignans. They are primarily found in fruits, Polyphenold, whole grains, Vegan high-protein meals, and seeds.
This group includes digeation, ellagic acid, digeston lignans. Poly;henols rich in these polyphenols include digeestion wine, turmeric, grapes, amd, raspberries, flax seeds, sesame seeds, and digestio grains.
The type Polyphenol amount of polyphenols Digestlon a particular food depends on its origin, ripeness, cultivation, digetion, and andd. Polyphenols are the most Polyphenos antioxidant ans the human body. Digestuon are known to neutralize harmful free diigestion in the body and prevent Vegan high-protein meals Polyphfnols cell damage.
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Dietary polyphenols have been shown Polyphemols improve abd by Concentration and mindfulness the growth of good gut bacteria and fighting off an ones.
For dogestion, polyphenols in green tea were proven to inhibit the growth of harmful bacteria and improve the symptoms of peptic ulcer disease PUDdiarrheaand inflammatory bowel disease IBD. A healthier gut with beneficial bacteria, viruses, and fungi helps prevent several digestive conditions, including:.
According to a studypolyphenols help probiotic bacteria such as Bifidobacterium and Lactobacillus thrive. Xnd act as prebiotics and are food to beneficial gut bacteria, promoting their numerical growth.
Additionally, the metabolites of these polyphenols improve gut health. Polyphenols have protective brain effects. As antioxidants, they protect your brain against neurotoxins and neuroinflammation.
Polyphenols have also been linked to improved brain function, including concentration and memory. Consuming polyphenol-rich foods such as grape juice, Ginkgo biloba, and cocoa has been shown to significantly boost cognition, attention, and memory in both young and old adults. A study also showed that polyphenols may help increase blood flow to the brain.
Additionally, they improve moods and combat depression. Green fruits and vegetables These include spinach, green apples, green tea, celery, olives, and asparagus.
They contain flavonoids, tannins, epigallocatechin gallate, vitexin, and isoflavones. These provide antioxidant and anti-inflammatory benefits, protecting the gut against chronic diseases. They also promote the growth of good gut bacteria like Bifidobacterium and Lactobacillus.
Blue fruits Blue fruits mostly contain flavonoids, procyanidins, flavonols, phenolic acids, and stilbenes. These provide antioxidant effects and prevent inflammation.
Examples include grapes, raisins, plums, blackberries, blueberries, prunes, and blackcurrants. Orange foods Orange foods such as Polypehnols, oranges, apricots, nectarines, peaches, and turmeric contain the following types of polyphenols: flavonols, phenolic acids, hesperidin, and curcuminoids.
They also provide antioxidant and anti-inflammatory benefits. Red fruits and vegetables Foods like red apples, cherries, tomatoes, strawberries, and red onions fall into this category. They contain phenolic acids, anthocyanins, flavonoids, and tannins. Yellow fruits and vegetables Examples are lemons, bananas, yellow onions, and yellow bell peppers.
They contain bioflavonoids, nobiletin, rutin, and hesperidin. They protect against stomach ulcers. Polyphenols are powerful plant chemicals that are important to our bodies and our overall health. Eating foods rich digetion polyphenols may improve digestion, increase brain function, and lower the risk of inflammation-related diseases.
These include gastrointestinal disorders, heart disease, cancers, neurodegenerative diseases, arthritis, and diabetes.
Natural foods remain the best sources of polyphenols. They may be found in legumes, fruits, vegetables, nuts, whole grains, and beverages. You may also take polyphenol supplements.
However, these may have side effects. Making dietary changes is often the first step to healing your gut issues. If you have concerns about gut issues, you can request an appointment online or call our office at Best Polyphenols for Your Gut?
Home Digestive Health Nutrition Best Polyphenols for Your Gut? Previous Next. What are Polyphenols? Types of Polyphenols There are more than 8, types of polyphenols. Polyphenolic amides This class of polyphenols includes capsaicinoids in chili peppers and avenanthramides in oats. Other polyphenols This group includes resveratrol, Polyphsnols acid, and lignans.
How do Polyphenols impact our Health? Polyphenols have been linked to several health benefits. Antioxidant and Anti-inflammatory Benefits Polyphenols are the most abundant antioxidant in the human body.
Gut microbiome Our gut microbiome is essential to our health. A healthy gut microbiota also helps with brain function and has neuroprotective effects. Influence your brain function Polyphenols have protective brain effects.
Best Polyphenols for Better Gut Health Using colors, the following are top polyphenol-rich foods that can improve your gut health. The Bottom Line Polyphenols are powerful plant chemicals that are important to our bodies and our overall health. About the Author: Sameer Islam MD. Sameer Islam is a functional gastroenterologist in Lubbock and is a Digestipn Texas native growing up in Odessa, Dkgestion.
He specializes in the comprehensive treatment of all digestive symptoms and conditions. His practice emphasizes promoting the awareness that colon cancer is a preventable and treatable cancer. Islam participates in local and national activities to further this awareness message.
Also, he has been recognized as a Fellow of Gastroenterology by the American College of Gastroenterology and the American Society for Gastrointestinal Endoscopy. Professional memberships include the American Medical Association, American College of Gastroenterology, American Gastroenterological Association, Texas Society for Gastroenterology and Endoscopy, Texas Medical Association, and Lubbock Medical Society.
To schedule an appointment, please contact Lubbock Gastroenterology located at 82nd Street, Suite 5, Lubbock, TX
: Polyphenols and digestion| Article information | This article reviews everything you need to know about polyphenols, including possible food sources. Polyphenols are a category of compounds naturally found in plant foods, such as fruits, vegetables, herbs, spices, tea, dark chocolate, and wine. They can act as antioxidants , meaning they can neutralize harmful free radicals that would otherwise damage your cells and increase your risk of conditions like cancer, diabetes, and heart disease 1. Polyphenols are also thought to reduce inflammation, which is thought to be the root cause of many chronic illnesses 2 , 3. More than 8, types of polyphenols have been identified. They can be further categorized into 4 main groups 4 , 5 :. The amount and type of polyphenols in foods depend on the food, including its origin, ripeness, and how it was farmed, transported, stored, and prepared. Polyphenol-containing supplements are available as well. Polyphenols are beneficial plant compounds with antioxidant properties that may help keep you healthy and protect against various diseases. They can be subdivided into flavonoids, phenolic acid, polyphenolic amides, and other polyphenols. Polyphenols may help lower your blood sugar levels , contributing to a lower risk of type 2 diabetes. Various studies further link polyphenol-rich diets to lower fasting blood sugar levels, higher glucose tolerance, and increased insulin sensitivity — all important factors in lowering your risk of type 2 diabetes 8. Among polyphenols, research suggests that anthocyanins may offer the most potent antidiabetic effect. Adding polyphenols to your diet may improve heart health. Experts believe that this is largely due to the antioxidant properties of polyphenols, which help reduce chronic inflammation, a risk factor for heart disease 3 , 12 , Two recent reviews link polyphenol supplements to lower blood pressure and LDL bad cholesterol levels, as well as higher HDL good cholesterol 14 , Lignans are a type of polyphenol typically found in flax seeds and whole grains Blood clots are formed when platelets circulating in your bloodstream begin to clump together. This process is known as platelet aggregation and is useful in preventing excess bleeding. However, excess platelet aggregation can cause blood clots, which can have negative health effects, including deep vein thrombosis, stroke, and pulmonary embolism According to test-tube and animal studies, polyphenols may help reduce the platelet aggregation process, thereby preventing the formation of blood clots 18 , 19 , Research consistently links diets rich in plant foods to a lower risk of cancer , and many experts believe that polyphenols are partly responsible for this 5 , 21 , Polyphenols have strong antioxidant and anti-inflammatory effects, both of which can be beneficial for cancer prevention A recent review of test-tube studies suggests that polyphenols may block the growth and development of various cancer cells 5 , In humans, some studies link high blood markers of polyphenol intake to a lower risk of breast and prostate cancers, while others find no effects. Therefore, more studies are needed before strong conclusions can be made Polyphenols may benefit digestion by promoting the growth of beneficial gut bacteria while fending off harmful ones 26 , For instance, evidence suggests that polyphenol-rich tea extracts can promote the growth of beneficial bifidobacteria Similarly, green tea polyphenols may help fight off harmful bacteria, including C. difficile , E. Coli , and Salmonella , as well as improve symptoms of peptic ulcer disease PUD and inflammatory bowel disease IBD 29 , Furthermore, emerging evidence indicates that polyphenols may help probiotics thrive and survive. These are beneficial bacteria that occur in certain fermented foods and can be taken in supplement form. However, more research is needed Polyphenol-rich foods may boost your focus and memory. One study reports that drinking grape juice, which is naturally rich in polyphenols, helped significantly boost memory in older adults with mild mental impairment in as little as 12 weeks Others suggest that cocoa flavanols may improve blood flow to the brain and have linked these polyphenols to improved working memory and attention 33 , 34 , 35 , Similarly, the polyphenol-rich plant extract Ginkgo biloba appears to boost memory, learning, and concentration. It has also been linked to improved brain activity and short-term memory in those with dementia Polyphenols may help prevent blood clots, reduce blood sugar levels, and lower heart disease risk. They may also promote brain function, improve digestion, and offer some protection against cancer, though more research is needed. Though tea, dark chocolate, red wine, and berries are likely the best-known sources of polyphenols, many other foods also contain high amounts of these beneficial compounds. Here are the 75 foods richest in polyphenols, listed by category Including foods from each of these categories in your diet provides you a wide variety of polyphenols. Many plant foods are naturally rich in polyphenols. Including a variety of these foods in your diet is a great strategy to boost your intake of these beneficial nutrients. Supplements have the advantage of offering a consistent dose of polyphenols. However, they also have several potential drawbacks. Moreover, polyphenols seem to work best when interacting with the many other nutrients naturally found in foods. Polyphenol supplements may not offer the same health benefits as polyphenol-rich foods. The same cannot be said of supplements, which tend to provide much higher quantities of polyphenols than those typically found in a healthy diet Animal studies show that high-dose polyphenol supplements may cause kidney damage, tumors, and an imbalance in thyroid hormone levels. In humans, they may result in an increased risk of stroke and premature death 39 , Some polyphenol-rich supplements can interact with nutrient absorption or interact with medications. If you have a diagnosed nutrient deficiency or are taking medications, it may be best to speak to your healthcare provider about polyphenol supplements before taking them. Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota. Res Microbiol. Hervert-Hernandez D, Pintado C, Rotger R, Goni I. Stimulatory role of grape pomace polyphenols on Lactobacillus acidophilus growth. Int J Food Microbiol. Tzonuis X, Vulevic J, Kuhnle GG, George T, Leonczak J, Gibson GR, et al. Flavanol monomer-induced changes to thehumanfaecalmicroflora. Br JNutr. Yamakoshi J, Tokutake S, Kikuchi M. Effect of proanthocyanidin- rich extract from grape seeds on human fecal flora andfecal odor. Microb Ecol Health Dis. Tzounis X, Rodriguez-Mateos A, Vulevic J, Gibson GR, Kwik-Uribe C, Spencer JP. Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, double-blind, crossover intervention study. Molan AL, Liu Z, Kruger M. The ability of blackcurrant extracts to positively modulate key markers of gastrointestinal function in rats. World J Microbiol Biotechnol. Viveros A, Chamorro S, Pizarro M, Arija I, Centeno C, Brenes A. Effects of dietary polyphenol-rich grape products on intestinal microflora and gut morphology in broiler chicks. Poult Sci. Queipo-Ortuño MI, Boto-Ordóñez M, Murri M, Gomez-Zumaquero JM, Clemente-Postigo M, Estruch R, et al. Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers. Vendrame S, Guglielmetti S, Riso P, Arioli S, Klimis-Zacas D, Porrini M. Six-week consumption of a wild blueberry powder drink increases bifidobacteria in the human gut. Cueva C, Sánchez-Patán F, Monagas M, Walton GE, Gibson GR, Martín-Álvarez PJ, et al. In vitro fermentation of grape seed flavanol fractions by human faecal microbiota: changes in microbial groups and phenolic metabolites. FEMS Microbiol Ecol. Koenig JE, Spor A, Scalfone N, Fricker AD, Stombaugh J, Knight R, et al. Succession of microbial consortia in the developing infant gut microbiome. Proc Natl Acad Sci USA. Sela DA, Chapman J, Adeuya A, Kim JH, Chen F, Whitehead TR, et al. The genome sequence of Bifidobacterium longum subsp infantis reveals adaptations for milk utilization within the infant microbiome. Palmer C, Bik EM, DiGiulio DB, Relman DA, Brown PO. Development of the human infant intestinal microbiota. PLoS Biol. Claesson MJ, Cusack S, O'Sullivan O, Greene-Diniz R, de Weerd H, Flannery E, et al. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Clemente JC, Ursell LK, Parfrey LW, Knight R. The impact of the gut microbiota on human health: an integrative view. Vinson JA, Su X, Zubik L, Bose P. Phenol antioxidant quantity and quality in foods: fruits. Kabera JN, Semana E, Mussa AR, He X. Plant secondary metabolites: biosynthesis, classification, function and pharmacological properties. J Pharm Pharmacol. Daglia M. Polyphenols as antimicrobial agents. Curr Opin Biotechnol. Quideau S, Deffieux D, Douat-Casassus C, Pouységu L. Plant polyphenols: chemical properties, biological activities, and synthesis. Angew Chem Int Ed. Hollman PCH, Katan MB. Dietary flavonoids: intake, health effects and bioavailability. Tomas-Barberan F, Clifford M. Dietary hydroxybenzoic acid derivatives and their possible role in health protection. J Sci Food Agric. CrossRef Full Text. Bhagwat S, Haytowitz DB, Holden JM. USDA Database for the Flavonoid Content of Selected Foods. Beltsville, MD: US Department of Agriculture. Google Scholar. Prasain JK, Grubbs C, Barnes S. Cranberry anti-cancer compounds and their uptake and metabolism: an updated review. Weber F, Larsen LR. Influence of fruit juice processing on anthocyanin stability. Food Res Int. Bataglion GA, da Silva FM, Eberlin MN, Koolen HH. Siriamornpun S, Kaewseejan N. Quality, bioactive compounds and antioxidant capacity of selected climacteric fruits with relation to their maturity. Sci Hortic. Bustamante-Rangel M, Delgado-Zamarreño MM, Pérez-Martín L, Rodríguez-Gonzalo E, Domínguez-Álvarez J. Analysis of isoflavones in foods. Compr Rev Food Sci Food Saf. Liggins J, Bluck LJ, Runswick S, Atkinson C, Coward WA, Bingham SA. Daidzein and genistein content of fruits and nuts. Tomé-Carneiro J, Larrosa M, González-Sarrías A, Tomas-Barberan F, Garcia-Conesa M, Carlos EJ. Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence. Curr Pharm Design. Khurana S, Venkataraman K, Hollingsworth A, Piche M, Tai T. Polyphenols: benefits to the cardiovascular system in health and in aging. Kuriyama S, Shimazu T, Ohmori K, Kikuchi N, Nakaya N, Nishino Y, et al. Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: the Ohsaki study. Meydani M, Hasan ST. Dietary polyphenols and obesity. Mursu J, Voutilainen S, Nurmi T, Tuomainen TP, Kurl S, Salonen JT. Flavonoid intake and the risk of ischaemic stroke and CVD mortality in middle-aged Finnish men: the Kuopio ischaemic heart disease risk factor study. Br J Nutr. Scalbert A, Manach C, Morand C, Rémésy C, Jiménez L. Dietary polyphenols and the prevention of diseases. Afshari K, Haddadi NS, Haj-Mirzaian A, Farzaei MH, Rohani MM, Akramian F, et al. Natural flavonoids for the prevention of colon cancer: a comprehensive review of preclinical and clinical studies. J Cell Physiol. Beara IN, Lesjak MM, Orcǐić DZ, Simin ND, Cětojević-Simin DD, BoŽin BN, et al. Comparative analysis of phenolic profile, antioxidant, anti-inflammatory and cytotoxic activity of two closely-related Plantain species: Plantago altissima L. and Plantago lanceolata L. LWT Food Sci Technol. Zimmer AR, Leonardi B, Miron D, Schapoval E, deOliveira JR, Gosmann G. Antioxidant and anti-inflammatory properties of Capsicum baccatum: from traditional use to scientific approach. Dos Santos MD, Almeida MC, Lopes NP, DeSouza GEP. Evaluation of the anti-inflammatory, analgesic and antipyretic activities of the natural polyphenol chlorogenic acid. Biol Pharm Bull. Xia D, Wu X, Shi J, Yang Q, Zhang Y. Phenolic compounds from the edible seeds extract of Chinese Mei Prunus mume Sieb. et Zucc and their antimicrobial activity. Protić D, Radunović N, Spremović-Radenović S, Živanović V, Heinle H, Petrović A, Gojković-Bukarica L. The role of potassium channels in the vasodilatation induced by resveratrol and naringenin in isolated human umbilical vein. Drug Dev Res. Gambini J, Inglés M, Olaso G, Lopez-Grueso R, Bonet-Costa V, Gimeno- Mallench L, et al. Properties of resveratrol: in vitro and in vivo studies about metabolism, bioavailability, and biological effects in animal models and humans. Oxidat Med Cell Long. Niedzwiecki A, Roomi MW, Kalinovsky T, Rath M. Anticancer efficacy of polyphenols and their combinations. Shim JS, Oh K, Kim HC. Dietary assessment methods in epidemiologic studies. Epidemiol Health. Del Bo C, Bernardi S, Marino M, Porrini M, Tucci M, Guglielmetti S, et al. Systematic review on polyphenol intake and health outcomes: is there sufficient evidence to define a health-promoting polyphenol-rich dietary pattern? Hein EM, Rose K, van't Slot G, Friedrich AW, Humpf HU. Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by fluorescence in situ hybridization FISH. Hirooka K, Fujita Y. Excess production of Bacillus subtilis quercetin 2, 3-dioxygenase affects cell viability in the presence of quercetin. Biosci Biotechnol Biochem. Schneider H, Simmering R, Hartmann L, Pforte H, Blaut M. Degradation of quercetinglucoside in gnotobiotic rats associated with human intestinal bacteria. J Appl Microbiol. Ireson CR, Jones DJ, Orr S, Coughtrie MW, Boocock DJ, Williams ML, et al. Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine. Cancer Epidemiol Prev Biomark. Bolca S, Urpi-Sarda M, Blondeel Ph, Roche N, Vanhaecke L, Possemiers S, et al. Disposition of soy isoflavones in normal breast tissue. van Dorsten FA, Grün CH, vanVelzen EJJ, Jacobs DM, Draijer R, van Duynhoven JPM. The metabolic fate of red wine and grape juice polyphenols in humans assessed by metabolomics. Lampe JW. Interindividual differences in response to plant based diets: implications for cancer risk. Kemperman RA, Bolca S, Roger LC, Vaughan EE. Novel approaches for analysing gut microbes and dietary polyphenols: challenges and opportunities. Sekirov I, Russell SL, Antunes LCM, Finlay BB. Gut microbiota in health and disease. Physiol Rev. Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, et al. Diversity of the human intestinal microbial flora. Huttenhower C, Gevers D, Knight R, Abubucker S, Badger JH, Chinwalla AT, et al. Structure, function and diversity of the healthy human microbiome. Krishnan S, Alden N, Lee K. Pathways and functions of gut microbiota metabolism impacting host physiology. Conlon MA, Bird AR. The impact of diet and lifestyle on gut microbiota and human health. Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, et al. Human gut microbiome viewed across age and geography. An R, Wilms E, Masclee AAM, Smidt H, Zoetendal EG, Jonkers D. Age-dependent changes in GI physiology and microbiota: time to reconsider? Claesson MJ, Jeery IB, Conde S, Power SE, O'Connor EM, Cusack S, et al. Gut microbiota composition correlates with diet and health in the elderly. Pascale A, Marchesi N, Marelli C, Coppola A, Luzi L, Govoni S, et al. Microbiota and metabolic diseases. Zuo T, Ng SC. The gut microbiota in the pathogenesis and therapeutics of inflammatory bowel disease. Front Microbiol. Brial F, LeLay A, Dumas ME, Gauguier D. Implication of gut microbiota metabolites in cardiovascular and metabolic diseases. Cell Mol Life Sci. Fernandes R, Viana SD, Nunes S, Reis F. Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy. Biochim Biophys Acta Mol Basis Dis. Ananthakrishnan AN. Epidemiology and risk factors for IBD. Nat Rev Gastroenterol Hepatol. Wedrychowicz A, Zajaç A, Tomasik P. Advances in nutritional therapy in inflammatory bowel diseases: review. World J Gastroenterol. Evenepoel P, Meijers BK, Bammens BR, Verbeke K. Uremic toxins originating from colonic microbial metabolism. Kidney Int. Duttona RJ, Turnbaugh PJ. Taking a metagenomic view of human nutrition. Curr Opin Clin Nutr Metab Care. Macdonald RS, Wagner K. Influence of dietary phytochemicals and microbiota on colon cancer. Woting A, Clavel T, Loh G, Blaut M. Bacterial transformation of dietary lignans in gnotobiotic rats. Mabrok HB, Klopfleisch R, Ghanem KZ, Clavel T, Blaut M, Loh G. Lignan transformation by gut bacteria lowers tumor burden in a gnotobiotic rat model of breast cancer. Namasivayam N. Chemoprevention in experimental animals. Ann N Y Acad Sci. Tulipani S, Urpi-Sarda M, García-Villalba R, Rabassa M, López-Uriarte P, Bullo M, et al. Urolithins are the main urinary microbial-derived phenolic metabolites discriminating a moderate consumption of nuts in free-living subjects with diagnosed metabolic syndrome. Miene C, Weise A, Glei M. Impact of polyphenol metabolites produced by colonic microbiota on expression of COX-2 and GSTT2 in human colon cells LT Kang NJ, Lee KW, Kim BH, Bode AM, Lee HJ, Heo YS, et al. Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK. McFadden RMT, Larmonier CB, Shehab KW, Midura-Kiela M, Ramalingam R, Harrison CA, et al. The role of curcumin in modulating colonic microbiota during colitis and colon cancer prevention. Inflamm Bowel Dis. Monagas M, Khan N, Andres-Lacueva C, Urpi-Sarda M, Vázquez-Agell M, Lamuela-Raventos RM, et al. Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells. Larrosa M, Luceri C, Vivoli E, Pagliuca C, Lodovici M, Moneti G, et al. Polyphenol metabolites from colonic microbiota exert anti-inflammatory activity on different inflammation models. Tucsek Z, Radnai B, Racz B, Debreceni B, Priber JK, Dolowschiak T, et al. Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: a critical role of MKP J Leukoc Biol. Beloborodova N, Bairamov I, Olenin A, Shubina V, Teplova V, Fedotcheva N. Effect of phenolic acids of microbial origin on production of reactive oxygen species in mitochondria and neutrophils. J Biomed Sci. Sharma S, Chopra K, Kulkarni S, Agrewala J. Clin Exp Immunol. Kumar Singh A, Cabral C, Kumar R, Ganguly R, Kumar Rana H, Gupta A, et al. Beneficial effects of dietary polyphenols on gut microbiota and strategies to improve delivery efficiency. Stapleton PD, Shah S, Ehlert K, Hara Y, Taylor PW. The beta-lactam-resistance modifier - -epicatechin gallate alters the architecture of the cell wall of Staphylococcus aureus. Tombola F, Campello S, De Luca L, Ruggiero P, Del Giudice G, Papini E, et al. Plant polyphenols inhibit VacA, a toxin secreted by the gastric pathogen Helicobacter pylori. FEBS Lett. Chan CL, Gan RY, Shah NP, Corke H. Polyphenols from selected dietary spices and medicinal herbs differentially affect common food-borne pathogenic bacteria and lactic acid bacteria. Food Control. Romier BYJ. Larondelle SY, During A. Dietary polyphenols can modulate the intestinal inflammatory response. Nutr Rev. Sergent TN, Meurice PJ, Toussaint O, Schneider YJ. Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium. Chem Biol Interact. Nicod N, Chiva-Blanch G, Giordano E, Davalos A, Parker RS, Visioli F. Green tea, cocoa, and red wine polyphenols moderately modulate intestinal inflammation and do not increase high-density lipoprotein HDL production. Romier-Crouzet B, Van De Walle J, During A, Joly A, Rousseau C, Henry O, et al. Inhibition of inflammatory mediators by polyphenolic plant extracts in human intestinal Caco-2 cells. Lee JS, Park SY, Thapa D, Choi MK, Chung IM, Park YJ, et al. Grifola frondosa water extract alleviates intestinal inflammation by suppressing TNF-a production and its signaling. Exp Mol Med. Biasi F, Guina T, Maina M, Cabboi B, Deiana M, Tuberoso CI, et al. Phenolic compounds present in Sardinian wine extracts protect against the production of inflammatory cytokines induced by oxysterols in CaCo-2 human enterocyte-like cells. Biochem Pharmacol. During A, Debouche C, Raas T, Larondelle Y. Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. Sengottuvelan M, Nalini N. Dietary supplementation of resveratrol suppresses colonic tumour incidence in 1,2-dimethylhydrazine-treated rats by modulating biotransforming enzymes and aberrant crypt foci development. Sanchez-Fidalgo S, Cardeno A, Villegas I, Talero E, de la Lastra CA. Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice. Eur J Pharmacol. Martin AR, Villegas I, La Casa C, de la Lastra CA. Resveratrol, a polyphenol found in grapes, suppresses oxidative damage and stimulates apoptosis during early colonic inflammation in rats. Singh UP, Singh NP, Singh B, Hofseth LJ, Price RL, Nagarkatti M, et al. Resveratrol trans-3,5,4'-trihydroxystilbene induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kappaB activation to abrogate dextran sulfate sodium-induced colitis. J Pharmacol Exp Ther. Etxeberria U, Arias N, Boqué N, Macarulla M, Portillo M, Martinez J, et al. Reshaping faecal gut microbiota composition by the intake of trans-resveratrol and quercetin in high-fat sucrose diet-fed rats. Isabel V, Susana SF, Alarcon DLLC. Chemopreventive effect of dietary curcumin on inflammationinduced colorectal carcinogenesis in mice. Ruan Z, Liu S, Zhou Y, Mi S, Liu G, Wu X, et al. Chlorogenic acid decreases intestinal permeability and increases expression of intestinal tight junction proteins in weaned rats challenged with LPS. PLoS ONE. Rosillo MA, Sanchez-Hidalgo M, Cardeno A, Alarcon de la Lastra C. Protective effect of ellagic acid, a natural polyphenolic compound, in a murine model of Crohn's disease. Syed U, Ganapasam S. Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1,2-dimethylhydrazineinduced rat colon carcinogenesis. Basic Clin Pharmacol Toxicol. Okazaki Y, Han Y, Kayahara M, Watanabe T, Arishige H, Kato N. Consumption of curcumin elevates fecal immunoglobulin A, an index of intestinal immune function, in rats fed a high-fat diet. Dolara P, Luceri C, De Filippo C, Femia AP, Giovannelli L, Caderni G, et al. Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F rats. Mutat Res Mol Mech Mutagen. Varilek GW, Yang F, Lee EY, deVilliers WJS, Zhong J, Oz HS, et al. Green tea polyphenol extract attenuates inflammation in interleukin-2—deficient mice, a model of autoimmunity. Lin G, Yan X, Liu D, Yang C, Huang Y, Zhao C. Role of green macroalgae enteromorpha prolifera polyphenols in the modulation of gene expression and intestinal microflora profiles in type 2 diabetic mice. Int J Mol Sci. Pandurangan AK, Mohebali N, Mohd N, Esa C, Y Looi Y, Ismail S, et al. Gallic acid suppresses inflammation in dextran sodium sulfate-induced colitis in mice: Possible mechanisms. Int Immunopharmacol. Canali R, Vignolini F, Nobili F, Mengheri E. Reduction of oxidative stress and cytokine-induced neutrophil chemoattractant CINC expression by red wine polyphenols in zinc deficiency induced intestinal damage of rat. Wang K, Jin X, Li Q, Sawaya ACHF, Le Leu RK, Conlon MA, et al. Propolis from different geographic origins decreases intestinal inflammation and Bacteroides spp. Populations in a Model of DSS-Induced Colitis. Kim YH, Kwon HS, Kim DH, Cho HJ, Lee HS, Jun JG, et al. Piceatannol, a stilbene present in grapes, attenuates dextran sulfate sodium-induced colitis. Massot-Cladera M, Abril-Gil M, Torres S, Franch A, Castell M, Perez-Cano FJ. Impact of cocoa polyphenol extracts on the immune system and microbiota in two strains of young rats. Perez-Berezo T, Franch A, Castellote C, Castell M, Perez-Cano FJ. Mechanisms involved in down-regulation of intestinal IgA in rats by high cocoa intake. Wang K, Wan Z, Ou A, Liang X, Guo X, Zhang Z, et al. Monofloral honey from a medical plant, Prunella Vulgaris, protected against dextran sulfate sodium-induced ulcerative colitis via modulating gut microbial populations in rats. Food Funct. Kim H, Banerjee N, Barnes RC, Pfent CM, Talcott ST, Dashwood RH, et al. Mol Carcinog. Taira T, Yamaguchi S, Takahashi A, Okazaki Y, Yamaguchi A, Sakaguchi H, et al. Dietary polyphenols increase fecal mucin and immunoglobulin A and ameliorate the disturbance in gut microbiota caused by a high fat diet. J Clin Biochem Nutr. Zanzer YC, Plaza M, Dougkas A, Turner C, Björck I, Östman E. Polyphenol-rich spice-based beverages modulated postprandial early glycaemia, appetite and PYY after breakfast challenge in healthy subjects: a randomised, single blind, crossover study. J Funct Food. Snopek L, Mlcek J, Sochorova L, Baron M, Hlavacova I, Jurikova T, et al. Contribution of redwine consumption to human health protection. Rastmanesh R. High polyphenol, low probiotic diet for weight loss because of intestinal microbiota interaction. Chem Interact. Limagne E, Thibaudin M, Euvrard R, Berger H, Chalons P, Végan F, et al. Sirtuin-1 activation controls tumor growth by impeding Th17 differentiation via STAT3 deacetylation. Cell Rep. Zhang Z, Wu X, Cao S, Cromie M, Shen Y, Feng Y, et al. Chlorogenic acid ameliorates experimental colitis by promoting growth of Akkermansia inmice. Ahn SC, Kim GY, Kim JH, Baik SW, Han MK, Lee HJ, et al. Epigallocatechingallate, constituent of green tea, suppresses the LPS-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and NF-κB. Biochem Biophys Res Commun. Kim GY, Kim KH, Lee SH, Yoon MS, Lee HJ, Moon DO, et al. Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-κB as potential targets. J Immunol. Kotla NG, Rana S, Sivaraman G, Sunnapu O, Vemula PK, Pandit A, et al. Bioresponsive drug delivery systems in intestinal inflammation: state-of-the-art and future perspectives. Adv Drug Deliv Rev. Chung JH, Lee SJ, Chung JO, Oh YJ, Hwang JA, Kim YK, et al. Effect of hydroxypropyl methyl cellulose phthalate coating on digestive stability and intestinal transport of green tea catechins. Integr Med Res. |
| What Are Polyphenols? Types, Benefits, and Food Sources | Phenolic compounds Vegan high-protein meals the edible seeds extract of Chinese Mei Polyphenols and digestion mume Digeston. These results suggest that potato phenolics may play a Tart cherry juice concentrate in ans of intestinal glucose transport and that these effects are translatable to consumer products such as potato chips. RefWorks RefWorks. Polyphenols are a category of compounds naturally found in plant foods, such as fruits, vegetables, herbs, spices, tea, dark chocolate, and wine. Loading related content. Potential risks and side effects. |
| Polyphenols: Benefits and Foods to Eat | Use profiles to select personalised advertising. You may accept or manage your choices by clicking below, including your right to object where legitimate interest is used, or at any time in the privacy policy page. They are primarily found in fruits, vegetables, whole grains, coffee, and seeds. Biosci Biotechnol Biochem. This article is part of the Research Topic Dietary Polyphenols for Improving Gut Health: Volume 1 View all 23 Articles. Blood clots are formed when platelets circulating in your bloodstream begin to clump together. Antioxidants Explained in Simple Terms. |
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