Body composition and metabolism -
Am J Physiol : E — E Muscelli E , Camastra S , Gastaldelli A , Natali A , Masoni A , Pecori N , Ferrannini E Influence of duration of obesity on the insulin resistance of obese non-diabetic patients.
Int J Obes Relat Metab Disord 22 : — Circ J 66 : — Matsuzawa Y Pathophysiology and molecular mechanisms of visceral fat syndrome: the Japanese experience. Diabetes Metab Rev 13 : 3 — Oflaz H , Ozbey N , Mantar F , Genchellac H , Mercanoglu F , Sencer E , Molvalilar S , Orhan Y Determination of endothelial function and early atherosclerotic changes in healthy obese women.
Diabetes Nutr Metab 16 : — Despres JP , Lamarche B Low-intensity endurance exercise training, plasma lipoproteins and the risk of coronary heart disease.
J Intern Med : 7 — Brochu M , Poehlman ET , Ades PA Obesity, body fat distribution, and coronary artery disease. J Cardiopulm Rehabil 20 : 96 — Salans LB , Cushman SW , Weismann RE Studies of human adipose tissue.
Adipose cell size and number in nonobese and obese patients. J Clin Invest 52 : — Ruderman N , Chisholm D , Pi-Sunyer X , Schneider S The metabolically obese, normal-weight individual revisited.
Dvorak RV , DeNino WF , Ades PA , Poehlman ET Phenotypic characteristics associated with insulin resistance in metabolically obese but normal-weight young women. Diabetes 48 : — N Engl J Med : — Katsuki A , Sumida Y , Urakawa H , Gabazza EC , Murashima S , Maruyama N , Morioka K , Nakatani K , Yano Y , Adachi Y Increased visceral fat and serum levels of triglyceride are associated with insulin resistance in Japanese metabolically obese, normal weight subjects with normal glucose tolerance.
Diabetes Care 26 : — Nyholm B , Mengel A , Nielsen S , Skjaerbaek C , Moller N , Alberti KG , Schmitz O Insulin resistance in relatives of NIDDM patients: the role of physical fitness and muscle metabolism. Diabetologia 39 : — Katzel LI , Bleecker ER , Colman EG , Rogus EM , Sorkin JD , Goldberg AP Effects of weight loss vs aerobic exercise training on risk factors for coronary disease in healthy, obese, middle-aged and older men.
A randomized controlled trial. JAMA : — Sharma AM Adipose tissue: a mediator of cardiovascular risk. Int J Obes Relat Metab Disord 26 : S5 — S7. Park KS , Rhee BD , Lee KU , Kim SY , Lee HK , Koh CS , Min HK Intra-abdominal fat is associated with decreased insulin sensitivity in healthy young men.
Metabolism 40 : — von Eyben FE , Mouritsen E , Holm J , Montvilas P , Dimcevski G , Suciu G , Helleberg I , Kristensen L , von Eyben R Intra-abdominal obesity and metabolic risk factors: a study of young adults. Int J Obes Relat Metab Disord 27 : — Seppala-Lindroos A , Vehkavaara S , Hakkinen AM , Goto T , Westerbacka J , Sovijarvi A , Halavaara J , Yki-Jarvinen H Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men.
J Clin Endocrinol Metab 87 : — Havel PJ Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin. Curr Opin Lipidol 13 : 51 — Ikezaki A , Hosoda H , Ito K , Iwama S , Miura N , Matsuoka H , Kondo C , Kojima M , Kangawa K , Sugihara S Fasting plasma ghrelin levels are negatively correlated with insulin resistance and PAI-1, but not with leptin, in obese children and adolescents.
Diabetes 51 : — Addy CL , Gavrila A , Tsiodras S , Brodovicz K , Karchmer AW , Mantzoros CS Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy.
J Clin Endocrinol Metab 88 : — Tschop M , Weyer C , Tataranni PA , Devanarayan V , Ravussin E , Heiman ML Circulating ghrelin levels are decreased in human obesity. Diabetes 50 : — Milan G , Granzotto M , Scarda A , Calcagno A , Pagano C , Federspil G , Vettor R Resistin and adiponectin expression in visceral fat of obese rats: effect of weight loss.
Obes Res 10 : — Koistinen HA , Vidal H , Karonen SL , Dusserre E , Vallier P , Koivisto VA , Ebeling P Plasma acylation stimulating protein concentration and subcutaneous adipose tissue C3 mRNA expression in nondiabetic and type 2 diabetic men. Arterioscler Thromb Vasc Biol 21 : — Dusserre E , Moulin P , Vidal H Differences in mRNA expression of the proteins secreted by the adipocytes in human subcutaneous and visceral adipose tissues.
Biochim Biophys Acta : 88 — Katsuki A , Sumida Y , Urakawa H , Gabazza EC , Murashima S , Matsumoto K , Nakatani K , Yano Y , Adachi Y Plasma levels of adiponectin are associated with insulin resistance and serum levels of triglyceride in Japanese metabolically obese, normal-weight men with normal glucose tolerance.
Sims EA Are there persons who are obese, but metabolically healthy? Metabolism 50 : — Frayn KN Adipose tissue as a buffer for daily lipid flux. Diabetologia 45 : — Oxford University Press is a department of the University of Oxford.
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Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents Abstract. The metabolically healthy, but obese MHO , individual. The metabolically obese, but normal weight MONW , individual.
Is there a role for adipose and gastrointestinal GI hormones in MHO and MONW individuals? Significance of the MHO and MONW subgroups in research and clinical medicine.
Journal Article. Metabolic and Body Composition Factors in Subgroups of Obesity: What Do We Know? Karelis , Antony D. Karelis, Unité Métabolique, Département de Nutrition, Université de Montréal, Chemin Cote Ste-Catherine, Pavillon Liliane de Stewart, Montréal, Québec, Canada H3T 1A8.
Oxford Academic. David H. Florence Conus. Remi Rabasa-Lhoret. Eric T. PDF Split View Views. Cite Cite Antony D. Select Format Select format. ris Mendeley, Papers, Zotero.
enw EndNote. bibtex BibTex. txt Medlars, RefWorks Download citation. Permissions Icon Permissions. Open in new tab Download slide. TABLE 1. Several selected metabolic characteristics of MHO and at risk individuals. Age yr Open in new tab.
TABLE 2. Age yr 29 ± 3 28 ± 4 Insulin sensitivity 6. metabolically healthy, but obese;. metabolically obese, but normal weight. OpenURL Placeholder Text.
Google Scholar PubMed. Obesity-associated disorders in normal-weight individuals: some speculations. Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome.
Google Scholar Crossref. Search ADS. Insulin action and age. Insulin resistance and hypersecretion in obesity. What are the physical characteristics associated with a normal metabolic profile despite a high level of obesity in postmenopausal women?
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study. Systemic resistance to the antilipolytic effect of insulin in black and white women with visceral obesity. Influence of duration of obesity on the insulin resistance of obese non-diabetic patients. Pathophysiology and molecular mechanisms of visceral fat syndrome: the Japanese experience.
Determination of endothelial function and early atherosclerotic changes in healthy obese women. Aurora, CO Fitness Center: WELL info cuanschutz. Clinic: Skip to content. CU Medicine Weight Management and Wellness Clinic School of Medicine. Toggle navigation.
University Quick Links. Shared Content Block: Styles -- all pages. Understand Your Body Composition and Metabolism. BOD POD® Knows Your Body The BOD POD® is a quick and easy scan that assesses your body composition.
Don't Just Blame Your Metabolism Your resting metabolic rate RMR is the number of calories energy that your body uses at rest. Thank you for your interest in the services offered at the CU Weight Management and Wellness Clinic. Fat tissue is made up of cells called adipocytes, which are hormonally active cells.
The greater the number of fat cells or the larger the fat cells are, then the higher the body fat percentage. Where fat is located in the body matters [17]. Scientists have also found that a higher fat deposition in your midsection , or a large waistline, is strongly associated with worse health outcomes [18].
This is because having a lot of belly fat may be more inflammatory a large waistline is actually one of the markers of metabolic syndrome. A higher percentage of belly fat is also associated with an increased risk for metabolic syndrome, T2D, and death [19].
In general, the higher proportion of fat mass to lean mass, the greater amount of insulin resistance you will have [19]. This is especially true in people with excess belly fat and is caused by increased free fatty acids and triglycerides in the blood, leading to insulin resistance [20].
This is an issue for several reasons. When you have insulin resistance, your body stops responding properly to insulin, making it harder for your cells to absorb glucose from the bloodstream.
This can lead to higher levels of circulating glucose and insulin in your blood — which promotes fat storage and triggers a vicious cycle that makes it hard to manage your weight.
High levels of glucose in your bloodstream over a long period can also have severe implications for your heart health , leading to decreased elasticity of your blood vessels making it harder for blood to pass through and increasing your risk of heart disease. That said, while having more fat mass than muscle mass increases your risk of insulin resistance, having increased muscle mass has a number of benefits, including improved insulin sensitivity, lipid profile, and blood pressure control as well as reduced mortality risk.
This is because muscles need glucose for energy, and the more muscle mass you have, the more glucose your muscles will absorb from your bloodstream.
On top of that, muscle is more metabolically active than fat i. Put simply, having more muscle mass and less fat mass can improve your metabolic health — and paying attention to body composition is more important than simply seeing the number on a scale go down.
But a healthier body composition can lead to better metabolism, and the first area of focus apart from a healthy diet is focusing on building lean mass, or muscle mass, to help you manage your weight.
Resistance training is key to improving body composition. Resistance training itself, even without dietary restrictions, can also lead to improved glycemic control, decreases in fat mass mostly visceral fat tissue , and better cardiovascular health outcomes.
Even just one hour per week of resistance training spread out between 2 sessions can help improve insulin sensitivity and build muscle mass. Moderate-intensity exercise can improve glucose tolerance and overall metabolic health, even without drastic changes in weight [23].
Aim to get 2. See our full list of exercises to improve insulin sensitivity. Losing weight may change body composition, but this weight may not be all fat mass — you may also be losing muscle mass.
You can improve your metabolic health and maintain muscle mass by having a diet that is overall high in protein, fiber , and fat, but lower in refined carbs [24]. These types of foods help give you stable blood sugar. Sardines, avocados, lentils, and berries are especially great for improving insulin sensitivity.
Time-restricted eating or caloric restriction , with or without exercise, can not only lead to decreased weight and a more favorable body composition, but may also help regulate glucose tolerance [25, 26]. Understanding your body composition in detail is crucial to better implementing a healthy lifestyle and food choices that benefit your personal physiology.
The 5 Best Exercises for Insulin Resistance and Metabolic Health. Metabolic Health.
Easy meal prep loss Controlling blood pressure naturally multiple beneficial effects on body composition and comppsition, but whether these depend on the Body composition and metabolism at which body weight Tart cherry juice capsules lost is not clear. We analyzed data Ad studies in which the same amount Boxy weight loss compossition induced rapidly or gradually. Thirteen studies were included in which the same percentage weight loss Lentils and soups achieved at slow or fast rates range: 0. Body composition and metabolism metabolim of weight loss metabolixm result in more fat-free mass and less fat mass being lost during the dynamic phase of weight reduction compared with slower rates of weight loss, in conjunction with greater declines in resting energy expenditure. However, these differences are attenuated after 2—4 weeks of stabilization at the new, lower body weight, and do not affect the rate and amount of weight regain 9—33 months later nor the tissue composition of regained weight. Differences in waist circumference, visceral and liver fat contents, resting blood pressure, fasting blood lipid profile, and insulin and adipokine concentrations in response to different rates of weight loss are trivial. Changes in body composition and metabolism after losing the same amount of body weight at different rates are largely similar, and occasional differences are likely not meaningful clinically for the long-term management of obesity and cardiometabolic diseases. You and Tart cherry juice capsules experts will have Compositon critical High-fat foods needed to structure your Tart cherry juice capsules ,etabolism monitor your amd. When it compsoition to weight loss, knowledge truly is power. FibroScan® for Liver Health. FibroScan® is an ultrasound device used to assess liver health without invasive tools. Your doctor will be able to measure liver stiffness and liver fat stores quickly and painlessly. This assessment tool helps us diagnose fatty liver disease early, and it is ideal for those experiencing obesity and metabolic diseases such as pre-diabetes, diabetes, or metabolic syndrome.
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