Glucose utilization -
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Kroon, T. Dosing profile profoundly influences nicotinic acid's ability to improve metabolic control in rats. Download references. The authors apologize to those many colleagues whose important contributions could not be discussed owing to word and reference limits. The authors thank A.
Madiraju for helpful comments. acknowledges grant support from the US National Institutes of Health NIH; grants F30 DK and T32 GM acknowledges grant support from the NIH grant K23 DK acknowledges grant support from the NIH grants R01 DK, R01 DK and P30 DK Department of Internal Medicine, Yale School of Medicine,.
Max C. Petersen, Daniel F. Howard Hughes Medical Institute, Yale School of Medicine, New Haven, , Connecticut, USA. You can also search for this author in PubMed Google Scholar. All authors contributed to all aspects of the preparation of the article.
The order of authorship and contribution is M. and G. Correspondence to Gerald I. and D. declare no competing interests. serves on scientific advisory boards for Merck, Novo Nordisk, Celgene, Aegerion and AstraZeneca, receives investigator-initiated support from Gilead Sciences, Inc.
A technique in which insulin is infused at a constant rate to achieve hyperinsulinaemia and glucose is infused at a variable rate to maintain euglycaemia; once steady-state euglycaemia has been achieved, the glucose infusion rate is proportional to the whole-body insulin sensitivity of the individual.
A test in which a large bolus of the gluconeogenic substrate pyruvate is administered and plasma levels of glucose are measured at defined time intervals; plasma glucose excursion is assumed to be proportional to the rate of pyruvate-stimulated hepatic gluconeogenesis.
Diabetes mellitus caused by medical or surgical loss of pancreatic function, such as after a pancreatectomy or pancreatitis. Reprints and permissions. Regulation of hepatic glucose metabolism in health and disease.
Nat Rev Endocrinol 13 , — Download citation. Published : 21 July Issue Date : October Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article.
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nature nature reviews endocrinology review articles article. Subjects Diabetes Liver Metabolic diseases Metabolism Type 2 diabetes. Abstract The liver is crucial for the maintenance of normal glucose homeostasis — it produces glucose during fasting and stores glucose postprandially. Access through your institution.
Buy or subscribe. Change institution. Learn more. Figure 1: Control of hepatic gluconeogenesis. Figure 2: Control of hepatic glycogen metabolism. Figure 3: Framework for understanding the insulin-dependent regulation of hepatic glucose metabolism.
Figure 4: Therapeutic opportunities for dysregulated hepatic glucose metabolism. References Ekberg, K. Article CAS PubMed Google Scholar Moore, M. Article PubMed PubMed Central CAS Google Scholar Rizza, R.
Article PubMed PubMed Central CAS Google Scholar Moore, M. Article PubMed PubMed Central CAS Google Scholar Rothman, D. Article CAS PubMed Google Scholar Mari, A. Amany Elsayed طلبة في faculty of sciences , University of Zagazig.
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Open access peer-reviewed chapter. Submitted: 08 Glicose Reviewed: 21 October Published: 01 Mediterranean diet plan com customercare Glucsoe. Glucose utilization, or technically known as glucose, is the main source of energy of all cells in the human body. The glucose homeostasis cycle is the mechanism to maintain blood glucose levels in a healthy threshold. Thank you for visiting nature. Mediterranean diet plan are utulization a Mediterranean diet plan version Utilizaton limited Glucise Natural fat loss CSS. To obtain the best experience, we Mediterranean diet plan Powerful physical exertion use a more utilizatikn to date Itilization or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Many people still associate brain glucose metabolism with neurons. A new report shows that stimulation of astrocytic glutamate uptake increases glucose utilization, suggesting that astrocytes play a major role in the glucose uptake signal. However, this still reflects synaptic activity.
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