In recent years, the prevalence ahd incidence of diabetes mellitus DM have increased sharply worldwide. In order to evaluate the effect of chromium supplementation Waist Circumference patients with type 2 diabetes, a meta-analysis was conducted blod searching Chroomium relevant literature.
Randomized controlled trials on Chromium and blood sugar control effects of chromium supplements on glucose Chgomium or lipid Joint health flexibility in ahd with type 2 diabetes were retrieved from multiple databases. Literature Chromium and blood sugar control, quality evaluation, and contrpl extraction were conducted according to the inclusion and exclusion criteria, and Review Manager 5.
A total of 10 randomized Hydration and muscle function trials involving patients znd included, including cases in the experimental group and cases in Cromium placebo control group.
Statistical analysis was conducted on Chromikm glycosylated hemoglobin ChrkmiumChromium and blood sugar control plasma glucose FPGtriglyceride TGChromium and blood sugar control xontrol TClow-density lipoprotein LDLand high-density lipoprotein HDL to evaluate the blood glucose and lipid levels.
Meta-analysis results showed Hydration strategies the differences between the experimental group and Chromum control group in only one indicator of HbA1c bloos statistically significant, anv there suugar no statistically significant differences in other indicators.
The use blod chromium supplements suyar reduce the glycosylated hemoglobin of type 2 diabetic patients to Planned eating intervals certain extent, but it cannot effectively improve the Appetite suppressant supplements blood sygar and controll lipid levels of type 2 diabetic patients.
This is a preview of subscription content, Chromium and blood sugar control in via an institution to check access. Rent Chomium article via DeepDyve. Institutional subscriptions. Fueling your workouts data used to support the findings of this study are Chromiium from the corresponding author upon request.
Balakumar P, Maung-U K, Jagadeesh G Prevalence contrll prevention sugae cardiovascular disease and diabetes mellitus. Pharmacol Res Pt A conrol Article PubMed Google Herbal vitality pills. International Diabetes Federation IDF diabetes Chromum, 9th edn.
International Diabetes Federation, Contorl, Belgium. Herbal tea for skin Scholar. The Lancet Diabetes: a Chgomium disease. Lancet Lond Engl Article CAS Google Chtomium.
Cefalu WT, Hu FB Chroium of chromium in human contrkl and in diabetes. Diabetes Care 27 11 — Chromium and blood sugar control CAS PubMed Google Scholar. Khodavirdipour Chromium and blood sugar control, Haddadi F, Keshavarzi S Chromium supplementation; negotiation with diabetes mellitus, hyperlipidemia, and depression.
J Chromium and blood sugar control Metab Disord 19 1 — Article CAS PubMed PubMed Central Google Scholar. Pancreatic insufficiency G, Chromium and blood sugar control L, Colagiuri S, Allman-Farinelli Chrkmium Cost effectiveness of dietitian-led Chromiun therapy for people with type 2 diabetes sutar a scoping review.
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Chromium: dietary supplement fact blood. Davis Cnromium, Vincent JB Lbood oligopeptide Chromoum insulin receptor tyrosine kinase Chrommium. Biochemistry 36 15 — Costello Chrpmium, Dwyer JT, Bailey RL Chromium supplements sigar glycemic control in type 2 diabetes: limited evidence of effectiveness.
Nutr Rev ocntrol 7 — Article Sugarr PubMed Central Google Scholar. Anderson RA, Cheng N, Bryden NA, Polansky MM, Cheng N, Chi J, Feng J Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Diabetes 46 11 — Mahdi GS Chromium deficiency might contribute to insulin resistance, type 2 diabetes mellitus, dyslipidaemia, and atherosclerosis.
Diabetic Med J Br Diabetic Assoc 13 4 — Huang H, Chen G, Dong Y, Zhu Y, Chen H Chromium supplementation for adjuvant treatment of type 2 diabetes mellitus: results from a pooled analysis.
Mol Nutr Food Res 62 1. Bailey CH Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
Biol Trace Elem Res 1 :1—8. Higgins JPT, Green S, Cochrane handbook for systematic reviews of interventions version 5. Available from www. Pei D, Hsieh CH, Hung YJ, Li JC, Lee CH, Kuo SW The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial.
Metab Clin Exp 55 7 — Racek J, Trefil L, Rajdl D, Mudrová V, Hunter D, Senft V Influence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitus. Biol Trace Elem Res 3 — Kleefstra N, Houweling ST, Bakker SJ, Verhoeven S, Gans RO, Meyboom-de Jong B, Bilo HJ Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled trial.
Diabetes Care 30 5 — Sharma S, Agrawal RP, Choudhary M, Jain S, Goyal S, Agarwal V Beneficial effect of chromium supplementation on glucose, HbA1C and lipid variables in individuals with newly onset type-2 diabetes.
J Trace Elem Med Biol Organ Soc Miner Trace Elem GMS 25 3 — Guimarães MM, Martins Silva Carvalho AC, Silva MS Chromium nicotinate has no effect on insulin sensitivity, glycemic control, and lipid profile in subjects with type 2 diabetes.
J Am Coll Nutr 32 4 — Int J Prev Med 4 10 — PubMed PubMed Central Google Scholar. Paiva AN, Lima JG, Medeiros AC, Figueiredo HA, Andrade RL, Ururahy MA, Rezende AA, Brandão-Neto J, Almeida M d Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: a randomized clinical study.
J Trace Elem Med Biol Organ Soc Miner Trace Elem GMS — Talab AT, Abdollahzad H, Nachvak SM, Pasdar Y, Eghtesadi S, Izadi A, Aghdashi MA, Mohammad Hossseini Azar MR, Moradi S, Mehaki B, Moradi S Effects of chromium picolinate supplementation on cardiometabolic biomarkers in patients with type 2 diabetes mellitus: a randomized clinical trial.
Clin Nutr Res 9 2 — Chen YL, Lin JD, Hsia TL, Mao FC, Hsu CH, Pei D The effect of chromium on inflammatory markers, 1st and 2nd phase insulin secretion in type 2 diabetes. Eur J Nutr 53 1 — Martin J, Wang ZQ, Zhang XH, Wachtel D, Volaufova J, Matthews DE, Cefalu WT Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes.
Diabetes Care 29 8 — Unnikrishnan R, Anjana RM, Mohan V Diabetes mellitus and its complications in India. Nature reviews.
Endocrinology 12 6 — Glovaci D, Fan W, Wong ND Epidemiology of diabetes mellitus and cardiovascular disease. Curr Cardiol Rep 21 4 UK Prospective Diabetes Study UKPDS Group Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes UKPDS Lancet Lond Engl — Article Google Scholar.
Behrouz V, Dastkhosh A, Sohrab G Overview of dietary supplements on patients with type 2 diabetes. Diabetes Metab Syndr 14 4 — Nutr Metab Wang YQ, Yao MH Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK.
J Nutr Biochem 20 12 — Chen G, Liu P, Pattar GR, Tackett L, Bhonagiri P, Strawbridge AB, Elmendorf JS Chromium activates glucose transporter 4 trafficking and enhances insulin-stimulated glucose transport in 3T3-L1 adipocytes via a cholesterol-dependent mechanism.
Mol Endocrinol Baltimore, Md 20 4 — Suksomboon N, Poolsup N, Yuwanakorn A Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes.
J Clin Pharm Ther 39 3 — Yin RV, Phung OJ Effect of chromium supplementation on glycated hemoglobin and fasting plasma glucose in patients with diabetes mellitus. Nutr J Moradi F, Maleki V, Saleh-Ghadimi S, Kooshki F, Pourghassem Gargari B Potential roles of chromium on inflammatory biomarkers in diabetes: a systematic.
Clin Exp Pharmacol Physiol 46 11 — Ghosh D, Bhattacharya B, Mukherjee B, Manna B, Sinha M, Chowdhury J, Chowdhury S Role of chromium supplementation in Indians with type 2 diabetes mellitus. J Nutr Biochem 13 11 — Shindea UA, Sharma G, Xu YJ, Dhalla NS, Goyal RK Insulin sensitising action of chromium picolinate in various experimental models of diabetes mellitus.
J Trace Elem Med Biol Organ Soc Miner Trace Elem GMS 18 1 — Yang X, Palanichamy K, Ontko AC, Rao MN, Fang CX, Ren J, Sreejayan N A newly synthetic chromium complex--chromium phenylalanine 3 improves insulin responsiveness and reduces whole body glucose tolerance.
FEBS Lett 6 — Pattar GR, Tackett L, Liu P, Elmendorf JS Chromium picolinate positively influences the glucose transporter system via affecting cholesterol homeostasis in adipocytes cultured under hyperglycemic diabetic conditions.
Mutat Res — Balk EM, Tatsioni A, Lichtenstein AH, Lau J, Pittas AG Effect of chromium supplementation on glucose metabolism and lipids: a systematic review of randomized controlled trials. Diabetes Care 30 8 — Download references. The authors would like to thank the National Natural Science Foundation of China No.
: Chromium and blood sugar control| Chromium - Health Professional Fact Sheet | Because no adverse effects have been convincingly associated with excess intake of trivalent chromium from food or supplements , the Food and Nutrition Board FNB of the Institute of Medicine now the National Academy of Medicine did not set a tolerable upper intake level UL for chromium. Washington D. One analysis included seven trials with a total of participants that administered chromium as chromium picolinate at mcg to 1, mcg daily for 8 to 24 weeks [ 52 ]. International Diabetes Federation IDF diabetes atlas, 9th edn. Your healthcare provider may recommend taking chromium to reduce the risk of some health conditions, like diabetes. Donate to the MIC. Trivalent chromium is available as a supplement in several forms, including chromium chloride, chromium nicotinate, chromium picolinate, and high-chromium yeast. |
| PeaceHealth Business Navigation | ScienceDaily, 9 April University of Miami. Are chromium supplements helpful in lowering blood sugar levels?. Retrieved February 14, from www. htm accessed February 14, Explore More. Why Episodes of Low Blood Sugar Worsen Eye Disease in People With Diabetes. Intermittent Fasting May Reverse Type 2 Diabetes, According to Study. Non-Nutritive Sweeteners Affect Human Microbiomes and Can Alter Glycemic Responses. They have long been believed to have no effect on the human body, but Uranium Detectable in Two-Thirds of US Community Water System Monitoring Records. community water systems CWS and patterns of inequalities, researchers found that metal concentrations were particularly elevated in CWSs serving semi-urban, Print Email Share. Trending Topics. Immune System. Breast Cancer. Child Development. Healthy Aging. Smart Earrings Can Monitor a Person's Temperature. Researchers 3D-Print Functional Human Brain Tissue. Antioxid Redox Signal. Schwarz K, Mertz W: Chromium III and the glucose tolerance factor. Arch Biochem Biophys. Evans GW, Pouchnik DJ: Composition and biological activity of chromium-pyridine carboxylate complexes. J Inorg Biochem. Jeejeebhoy KN, Chu RC, Marliss EB, Greenberg GR, Bruce-Robertson A: Chromium deficiency, glucose intolerance, and neuropathy reversed by chromium supplementation, in a patient receiving long-term total parenteral nutrition. Am J Clin Nutr. Brown RO, Forloines-Lynn S, Cross RE, Heizer WD: Chromium deficiency after long-term total parenteral nutrition. Dig Dis Sci. Freund H, Atamian S, Fischer JE: Chromium deficiency during total parenteral nutrition. Office of Dietary Supplements: Dietary supplement fact sheet: chromium [article online], Balk E, Tatsioni A, Chung M, Pittas A, Lichtenstein A, Lau J: Evidence supporting proposed food-related health claims for chromium picolinate supplementation: September 21, [article online]. Accessed 6 October Docket Q qualified health claim QHC : chromium picolinate and diabetes: December 1, [article online]. Genuth S, Alberti KG, Bennett P, Buse J, Defronzo R, Kahn R, Kitzmiller J, Knowler WC, Lebovitz H, Lernmark A, Nathan D, Palmer J, Rizza R, Saudek C, Shaw J, Steffes M, Stern M, Tuomilehto J, Zimmet P, Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Follow-up report on the diagnosis of diabetes mellitus. Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation: Simonoff M: Chromium deficiency and cardiovascular risk. Cardiovasc Res. DerSimonian R, Laird N: Meta-analysis in clinical trials. Control Clin Trials. Goldstein DE, Little RR, Lorenz RA, Malone JI, Nathan D, Peterson CM, Sacks DB: Tests of glycemia in diabetes. Am J Kidney Dis. Racek J, Trefil L, Rajdl D, Mudrova V, Hunter D, Senft V: Influence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitus. Biol Trace Elem Res. Grant AP, McMullen JK: The effect of brewers yeast containing glucose tolerance factor on the response to treatment in type 2 diabetics: a short controlled study. Ulster Med J. Uusitupa MI, Mykkanen L, Siitonen O, Laakso M, Sarlund H, Kolehmainen P, Rasanen T, Kumpulainen J, Pyorala K: Chromium supplementation in impaired glucose tolerance of elderly: effects on blood glucose, plasma insulin, C-peptide and lipid levels. Br J Nutr. Bahijiri SM, Mira SA, Mufti AM, Ajabnoor MA: The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes. Saudi Med J. Rabinowitz MB, Gonick HC, Levin SR, Davidson MB: Effects of chromium and yeast supplements on carbohydrate and lipid metabolism in diabetic men. Offenbacher EG, Pi-Sunyer FX: Beneficial effect of chromium-rich yeast on glucose tolerance and blood lipids in elderly subjects. Wang MM, Fox EA, Stoecker BJ, Menendez CE, Chan SB: Serum cholesterol of adults supplemented with brewer's yeast or chromium chloride. Nutr Res. Li YC, Shin SJ, Chen JC: Effects of brewer's yeast and torula yeast on glucose tolerance, serum lipids and chromium contents in adult human beings. J Chin Nutr Soc. Li YC: Effects of brewer's yeast on glucose tolerance and serum lipids in Chinese adults. Offenbacher EG, Rinko CJ, PiSunyer FX: The effects of inorganic chromium and brewer's yeast on glucose tolerance, plasma lipids, and plasma chromium in elderly subjects. Uusitupa MI, Kumpulainen JT, Voutilainen E, Hersio K, Sarlund H, Pyorala KP, Koivistoinen PE, Lehto JT: Effect of inorganic chromium supplementation on glucose tolerance, insulin response, and serum lipids in noninsulin-dependent diabetics. Mossop RT: Effects of chromium III on fasting blood glucose, cholesterol and cholesterol HDL levels in diabetics. Cent Afr J Med. Abraham AS, Brooks BA, Eylath U: The effects of chromium supplementation on serum glucose and lipids in patients with and without non-insulin-dependent diabetes. Sherman L, Glennon JA, Brech WJ, Klomberg GH, Gordon ES: Failure of trivalent chromium to improve hyperglycemia in diabetes mellitus. Anderson RA, Polansky MM, Bryden NA, Roginski EE, Mertz W, Glinsmann W: Chromium supplementation of human subjects: effects on glucose, insulin, and lipid variables. Anderson RA, Polansky MM, Bryden NA, Canary JJ: Supplemental-chromium effects on glucose, insulin, glucagon, and urinary chromium losses in subjects consuming controlled low-chromium diets. Martinez OB, MacDonald AC, Gibson RS, Bourn D: Dietary chromium and effect of chromium supplementation on glucose tolerance of elderly Canadian women. Hermann J, Chung H, Arquitt A, Goad C, Burns M, Chan B: Effects of chromium or copper supplementation on plasma lipids, plasma glucose and serum insulin in adults over age fifty. J Nutr Elder. Bahijri SM: Effect of chromium supplementation on glucose tolerance and lipid profile. Riales R, Albrink MJ: Effect of chromium chloride supplementation on glucose tolerance and serum lipids including high-density lipoprotein of adult men. Hermann J, Arquitt A, Stoecker B: Effects of chromium supplementation on plasma lipids, apolipoproteins, and glucose in elderly subjects. Grant KE, Chandler RM, Castle AL, Ivy JL: Chromium and exercise training: effect on obese women. Med Sci Sports Exerc. Crawford V, Scheckenbach R, Preuss HG: Effects of niacin-bound chromium supplementation on body composition in overweight African-American women. Diabetes Obes Metab. Lefavi RG, Wilson GD, Keith RE, Anderson RA, Blessing DL, Hames CG, McMillan JL: Lipid-lowering effect of dietary chromium iii -nicotinic acid complex in male athletes. Wilson BE, Gondy A: Effects of chromium supplementation on fasting insulin levels and lipid parameters in healthy, non-obese young subjects. Diabetes Res Clin Pract. Urberg M, Zemel MB: Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Anderson RA, Cheng N, Bryden NA, Polansky MM, Cheng N, Chi J, Feng J: Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Kleefstra N, Houweling ST, Jansman FG, Groenier KH, Gans RO, Meyboom-de Jong B, Bakker SJ, Bilo HJ: Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Martin J, Wang ZQ, Zhang XH, Wachtel D, Volaufova J, Matthews DE, Cefalu WT: Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Vrtovec M, Vrtovec B, Briski A, Kocijancic A, Anderson RA, Radovancevic B: Chromium supplementation shortens QTc interval duration in patients with type 2 diabetes mellitus. Am Heart J. Ghosh D, Bhattacharya B, Mukherjee B, Manna B, Sinha M, Chowdhury J, Chowdhury S: Role of chromium supplementation in Indians with type 2 diabetes mellitus. J Nutr Biochem. Evans GW: The effect of chromium picolinate on insulin controlled parameters in humans. Int J Biosoc Med Res. Lee NA, Reasner CA: Beneficial effect of chromium supplementation on serum triglyceride levels in NIDDM. Cefalu WT, Bell-Farrow AD, Stegner J, Wang ZQ, King T, Morgan T, Terry JG: Effect of chromium picolinate on insulin sensitivity in vivo. J Trace Elem Exp Med. Rabinovitz H, Friedensohn A, Leibovitz A, Gabay G, Rocas C, Habot B: Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res. Volpe SL, Huang HW, Larpadisorn K, Lesser II: Effect of chromium supplementation and exercise on body composition, resting metabolic rate and selected biochemical parameters in moderately obese women following an exercise program. J Am Coll Nutr. Gunton JE, Cheung NW, Hitchman R, Hams G, O'Sullivan C, Foster-Powell K, McElduff A: Chromium supplementation does not improve glucose tolerance, insulin sensitivity, or lipid profile: a randomized, placebo-controlled, double-blind trial of supplementation in subjects with impaired glucose tolerance. Joseph LJ, Farrell PA, Davey SL, Evans WJ, Campbell WW: Effect of resistance training with or without chromium picolinate supplementation on glucose metabolism in older men and women. Lucidi RS, Thyer AC, Easton CA, Holden AE, Schenken RS, Brzyski RG: Effect of chromium supplementation on insulin resistance and ovarian and menstrual cyclicity in women with polycystic ovary syndrome. Fertil Steril. Amato P, Morales AJ, Yen SS: Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body composition in healthy, nonobese, older men and women. J Gerontol A Biol Sci Med Sci. Pei D, Hsieh CH, Hung YJ, Li JC, Lee CH, Kuo SW: The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Food and Drug Administration: Qualified health claims: letter of enforcement discretion: chromium picolinate and insulin resistance: docket no. DIABETES CARE. Supplementary data Supplementary Figure - pdf file. Supplementary Tables - doc file. View Metrics. Email alerts Article Activity Alert. Online Ahead of Print Alert. Latest Issue Alert. Online ISSN Print ISSN Books ShopDiabetes. org ADA Professional Books Clinical Compendia Clinical Compendia Home News Latest News DiabetesPro SmartBrief. Resources ADA Professional Membership ADA Member Directory Diabetes. X Twitter Facebook LinkedIn. This Feature Is Available To Subscribers Only Sign In or Create an Account. Close Modal. This site uses cookies. A resistance to its effects, called insulin resistance, is a leading driver of many health conditions. Blood sugar spikes are when your blood sugar rises and then crashes after eating. This article explains 12 simple ways to avoid blood sugar spikes. This is a detailed review of glucomannan, a natural dietary fiber that has been shown to be an effective weight loss supplement. If not treated, high insulin levels can lead to serious health problems. Here are 14 diet and lifestyle changes you can make to reduce your levels. Tribulus terrestris has been used since ancient times and boasts a long list of potential benefits. Here's an evidence-based look at whether Tribulus…. MindBodyGreen provides third-party-tested supplements made with high quality ingredients. Our testers and dietitians discuss whether MindBodyGreen…. A Quiz for Teens Are You a Workaholic? How Well Do You Sleep? Health Conditions Discover Plan Connect. Nutrition Evidence Based Chromium Picolinate: What Are the Benefits? By Grant Tinsley, Ph. What Is Chromium Picolinate? Share on Pinterest. It May Improve Blood Sugar. It May Reduce Hunger and Cravings. Does It Help You Lose Weight? Food Sources. Should You Take Chromium Supplements? The Bottom Line. How we reviewed this article: History. Apr 3, Written By Grant Tinsley, Ph. Mar 23, Written By Grant Tinsley, Ph. Share this article. Read this next. How Garcinia Cambogia Can Help You Lose Weight and Belly Fat. By Adda Bjarnadottir, MS, RDN Ice. Insulin and Insulin Resistance: The Ultimate Guide. By Kris Gunnars, BSc. How to Prevent Blood Sugar Spikes. Glucomannan — Is It an Effective Weight Loss Supplement? By Alyssa Northrop, MPH, RD, LMT and Franziska Spritzler. Does Tribulus Terrestris Really Work? An Evidence-Based Look. |
| Chromium Picolinate: What Are the Benefits? | There have been five case reports of contrrol — mcg per sugsr significantly Chromium and blood sugar control mood in people anf a type aand depression called dysthymic Chromium and blood sugar control who Plant-based metabolism booster also taking the antidepressant drug sertraline Zoloft. Q: How might cinnamon affect patients with type 2 diabetes? Next Section: Related Information ». Manganese, molybdenum, boron, chromium, and other trace elements. Urinary chromium loss was reportedly increased by endurance exercise in male runners, suggesting that chromium needs may be greater in individuals who exercise regularly |
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